{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:36:29Z","timestamp":1786739789362,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T00:00:00Z","timestamp":1780012800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,6]]},"abstract":"\n Context:<\/jats:title>\n \n The antimicrobial activity of probiotics determined by colony-forming units when used against\n Enterococcus faecalis<\/jats:italic>\n thereby can be used as an alternative intracanal medicament in root canal therapy.\n <\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n \n To evaluate the two commercially available probiotics antibacterial effectiveness against\n E. faecalis<\/jats:italic>\n in root canal treatment.\n <\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n \n In vitro<\/jats:italic>\n study.\n <\/jats:p>\n <\/jats:sec>\n \n Subjects and Methods:<\/jats:title>\n \n Sixty-two extracted mandibular premolars were decoronated and instrumented up to ProTaper Gold F2 (Dentsply, USA) using 2.5% sodium hypochlorite irrigation followed by 17% ethylenediaminetetraacetic acid. Samples were autoclaved and inoculated with the test organism\n E. faecalis<\/jats:italic>\n (American Type Culture Collection (ATCC) 29212) for 7 days, kept in a sealed container at 37\u00b0C. Sixty samples were divided into four groups (\n n<\/jats:italic>\n = 15): Group 1 \u2013 Cyraflora (\n Saccharomyces boulardii<\/jats:italic>\n ), Group 2 \u2013 Econorm (\n Bacillus<\/jats:italic>\n species), Group 3 \u2013 2% chlorhexidine gel, and Group 4 \u2013 calcium hydroxide. Then, the respective intracanal medicaments were placed inside the root canal space and sealed with glass ionomer cement (GIC). After 7 days, coronal GIC was removed, irrigated, dried, and dentinal scrappings were taken by using H files, and bacterial counts were evaluated.\n <\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis:<\/jats:title>\n One-way analysis of variance was used to examine the data, and the Wilcoxon signed-rank test was used for intergroup comparisons.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The findings demonstrated the efficacy of probiotics\n S. boulardii<\/jats:italic>\n and\n Bacillus<\/jats:italic>\n species against\n E. faecalis<\/jats:italic>\n , with a decrease in colony-forming units following probiotic use.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n As an alternate intracanal medication, probiotics can be utilized to effectively combat\n E. faecalis.<\/jats:italic>\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jcde.jcde_52_26","type":"journal-article","created":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T17:08:20Z","timestamp":1780074500000},"page":"587-591","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of antimicrobial efficacy of two commercially available probiotics against Enterococcus faecalis: An in vitro study"],"prefix":"10.4103","volume":"29","author":[{"given":"A. 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