{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T23:25:05Z","timestamp":1789428305476,"version":"build-2803163510"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,2]]},"abstract":"Abstract<\/jats:title>\n \n Aim and Objectives:<\/jats:title>\n The aim of the study was to evaluate the influence of photodynamic and sonodynamic disinfection on the bond strength of caries-affected dentin bonded to three different restorative materials, i.e. Cention N, RMGIC, and Synergy D6.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n One hundred and eight carious and 18 noncarious teeth were collected, ground to expose affected dentin, and were arbitrarily allocated into 12 groups (n = 9). Fifty-four samples were disinfected with photodynamic therapy (PDT) and the other half with sonodynamic therapy (SDT). Samples were further randomly subdivided based on photosensitizers used methylene blue (M) (100 mg\/ml) or indocyanine green (I) (500 mg\/ml). Each sample was bonded to Cention N (C)\/RMGIC (R)\/Synergy D6 (S) and was subjected to shear bond strength (SBS) testing. Data were analyzed using ANOVA,\n post hoc<\/jats:italic>\n Tukey, and unpaired t-test and the level of significance was established at\n P<\/jats:italic>\n \u2264 0.05.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n All tested materials showed the highest SBS with SDT irrespective to the dye used. Indocyanine green enhanced the SBS of all tested materials compared to methylene blue (\n P<\/jats:italic>\n < 0.05) (photodynamic indocyanine Synergy D6 vs. photodynamic methylene Synergy D6 = 8.61, 7.16; photodynamic indocyanine RMGIC vs. photodynamic methylene RMGIC = 4.95, 4.06; photodynamic indocyanine Cention N vs. photodynamic methylene Cention N = 6.44, 5.56 and sonodynamic indocyanine Synergy D6 vs. sonodynamic methylene Synergy D6 = 9.52, 8.53; sonodynamic indocyanine RMGIC vs. sonodynamic methylene RMGIC = 9.75, 5.37; sonodynamic indocyanine Cention N vs. sonodynamic methylene Cention N = 7.48, 6.44).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Besides their antimicrobial action, PDT and SDT techniques can augment the bond strength of carious dentin with restorative material. Nanocomposites bond stronger postdisinfection as compared to RMGIC and Cention N.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jcde.jcde_532_24","type":"journal-article","created":{"date-parts":[[2025,2,3]],"date-time":"2025-02-03T01:00:38Z","timestamp":1738544438000},"page":"193-198","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Influence of photodynamic and sonodynamic disinfection on the bond strength of caries-affected dentin bonded to three different tooth-colored restorative materials: A comparative study"],"prefix":"10.4103","volume":"28","author":[{"given":"Ayushi","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalya","family":"Raj","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vineeta","family":"Nikhil","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Ravider","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, Subharti Dental College and Hospital, Swami Vivekanand Subharti University, Meerut, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,2,3]]},"reference":[{"key":"R1-20250212","doi-asserted-by":"crossref","first-page":"705","DOI":"10.14219\/jada.archive.2008.0252","article-title":"Treatment of deep carious lesions by complete excavation or partial removal: A critical review","volume":"139","author":"Thompson","year":"2008","journal-title":"J Am Dent Assoc"},{"key":"R2-20250212","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s00784-017-2221-0","article-title":"Partial caries removal in deep caries lesions: A 5-year multicenter randomized controlled trial","volume":"22","author":"Maltz","year":"2018","journal-title":"Clin Oral Investig"},{"key":"R3-20250212","doi-asserted-by":"crossref","first-page":"102261","DOI":"10.1016\/j.pdpdt.2021.102261","article-title":"Bonding of an ion-releasing restorative material to caries-affected dentin disinfected with photodynamic therapy, Er, Cr: YSGG laser, and chemical disinfectants","volume":"34","author":"Keskin","year":"2021","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"R4-20250212","doi-asserted-by":"crossref","first-page":"101865","DOI":"10.1016\/j.pdpdt.2020.101865","article-title":"Treatment of caries affected dentin with different photosensitizers and its effect on adhesive bond integrity to resin composite","volume":"31","author":"Alrahlah","year":"2020","journal-title":"Photodiagnosis Photodyn Ther"},{"key":"R5-20250212","first-page":"39","article-title":"Disinfection by methylthionine chloride and chitosan in combination with photo radiation therapy on caries affected dentin Nano hardness, adhesive integrity, and bond failure","volume":"28","author":"Alanazi","year":"2024","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"R6-20250212","first-page":"214","article-title":"Effect of dental acid etchant-mediated photodynamic therapy on bacterial reduction and microshear bond strength of composite to dentin \u2013 An in vitro study","volume":"24","author":"Gupta","year":"2021","journal-title":"J Conserv Dent Endod"},{"key":"R7-20250212","first-page":"502","article-title":"Comparative evaluation of the antimicrobial efficacy of nanoparticle-mediated photodynamic therapy versus photodynamic therapy and conventional disinfection in endodontics: A systematic review and meta-analysis","volume":"26","author":"Yarlagadda","year":"2023","journal-title":"J Conserv Dent Endod"},{"key":"R8-20250212","doi-asserted-by":"crossref","first-page":"101875","DOI":"10.1016\/j.pdpdt.2020.101875","article-title":"Efficacy of chlorhexidine, Er Cr YSGG laser and photodynamic therapy on the adhesive bond integrity of caries affected dentin. 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