{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:22:14Z","timestamp":1787775734501,"version":"build-2784847793"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"\n Objectives:<\/jats:title>\n The objectives of this study were to assess the salivary flow rate, pH, buffering capacity, and glycoproteins levels in root caries-active and root caries (RC)-free subjects.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n A cross-sectional study was conducted in the Outpatient Department of A B Shetty Memorial Institute of Dental Sciences with a sample size of 94 subjects. After screening of the subjects, the salivary samples were collected from 47 RC-active and 47 RC-free subjects for analysis. The following parameters were assessed \u2013 salivary flow rate, pH, buffer capacity, levels of salivary amylase, mucin, albumin, globulin, and total salivary protein.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Age was significantly higher in the RC group compared to the non-RC group (\n P<\/jats:italic>\n < 0.001). There was no significant difference in pH between the groups (\n P<\/jats:italic>\n = 0.050). Median buffer capacity and flow rate were higher in the non-RC group compared to the RC group. There was a significant difference in buffer capacity (\n P<\/jats:italic>\n < 0.001) and flow rate (\n P<\/jats:italic>\n = 0.001) between the RC and non-RC groups. There was no significant difference in total protein level (\n P<\/jats:italic>\n = 0.285) in the non-RC and RC groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The study demonstrated reduced salivary flow and buffer capacity, along with lower albumin levels and higher mucin-1 concentrations in individuals with RC. The salivary analysis provides a noninvasive and effective approach to assess RC risk. Incorporating salivary diagnostics into routine dental check-ups, particularly for older patients, can help in tailoring preventive care and treatment plans.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jcde.jcde_791_24","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T01:00:27Z","timestamp":1746493227000},"page":"406-411","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Salivary analysis in adults with and without root caries in South coastal population of India - A cross-sectional analytical study"],"prefix":"10.4103","volume":"28","author":[{"given":"Jyothi","family":"Shetty","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, A B Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mithra N.","family":"Hegde","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics, A B Shetty Memorial Institute of Dental Sciences, Nitte (Deemed to be University), Mangalore, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. 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