{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:48:28Z","timestamp":1787071708408,"version":"build-2736575974"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Peripartum cardiomyopathy (PPCM) is a condition of myocardial systolic dysfunction with dilated cardiomyopathy phenotype which occurs in the last months of pregnancy to several months postpartum period. There are several predictors of poor recovery in PPCM, especially severe left ventricular (LV) systolic dysfunction at initial presentation. We reported a case of a 41-year-old woman with late presenter PPCM and the presence of poor predictors of recovery from echocardiographic parameters. Echocardiography showed severely reduced ventricular function and global hypokinetic LV with severe tricuspid regurgitation. After 6 months of guideline-directed medical treatment (GDMT) for heart failure (HF) with reduced ejection fraction, complete ventricular reverse remodeling which evaluated by conventional echocardiography parameters. In addition to that, global longitudinal strain and myocardial work index assessment by echocardiographic evaluation also showed progressive myocardial recovery. This case highlights the role and efficacy of HF GDMT in late presenter PPCM and emphasizes the importance of meticulous echocardiographic evaluation with the purpose to track the therapeutic response in the presence of poor prognostic factors in patients.<\/jats:p>","DOI":"10.4103\/jcecho.jcecho_102_24","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:00:31Z","timestamp":1759294831000},"page":"280-284","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Reverse Remodeling in Late Presenter Peripartum Cardiomyopathy: Strain and Myocardial Work Analysis"],"prefix":"10.4103","volume":"35","author":[{"given":"Mochamad Rizky","family":"Hendiperdana","sequence":"first","affiliation":[{"name":"Cardiovascular Division, Pandan Arang General Hospital, Boyolali, Central Java, Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"R1-20251010","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jacc.2019.11.014","article-title":"Peripartum cardiomyopathy: JACC state-of-the-art review","volume":"75","author":"Davis","year":"2020","journal-title":"J Am Coll Cardiol"},{"key":"R2-20251010","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1111\/echo.13277","article-title":"Longitudinal systolic strain profiles and outcomes in peripartum cardiomyopathy","volume":"33","author":"Briasoulis","year":"2016","journal-title":"Echocardiography"},{"key":"R3-20251010","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1093\/eurjhf\/hfs070","article-title":"Delayed recovery in peripartum cardiomyopathy: An indication for long-term follow-up and sustained therapy","volume":"14","author":"Biteker","year":"2012","journal-title":"Eur J Heart Fail"},{"key":"R4-20251010","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.jacc.2015.06.1309","article-title":"Clinical outcomes for peripartum cardiomyopathy in North America: Results of the IPAC study (investigations of pregnancy-associated cardiomyopathy)","volume":"66","author":"McNamara","year":"2015","journal-title":"J Am Coll Cardiol"},{"key":"R5-20251010","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1007\/s00395-013-0366-9","article-title":"Phenotyping and outcome on contemporary management in a German cohort of patients with peripartum cardiomyopathy","volume":"108","author":"Haghikia","year":"2013","journal-title":"Basic Res Cardiol"},{"key":"R6-20251010","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3389\/fcvm.2020.00004","article-title":"The role of multimodality cardiovascular imaging in peripartum cardiomyopathy","volume":"7","author":"Ricci","year":"2020","journal-title":"Front Cardiovasc Med"},{"key":"R7-20251010","doi-asserted-by":"crossref","first-page":"2279018","DOI":"10.1080\/14767058.2023.2279018","article-title":"Predicting poor left ventricular function recovery in peripartum cardiomyopathy","volume":"36","author":"Prameswari","year":"2023","journal-title":"J Matern Fetal Neonatal Med"},{"key":"R8-20251010","doi-asserted-by":"crossref","first-page":"3599","DOI":"10.1093\/eurheartj\/ehab368","article-title":"2021 ESC guidelines for the diagnosis and treatment of acute and chronic heart failure","volume":"42","author":"McDonagh","year":"2021","journal-title":"Eur Heart J"},{"key":"R9-20251010","doi-asserted-by":"crossref","first-page":"964","DOI":"10.1002\/ehf2.12656","article-title":"Short-term echocardiographic evaluation by global longitudinal strain in patients with heart failure treated with sacubitril\/valsartan","volume":"7","author":"Mazzetti","year":"2020","journal-title":"ESC Heart Fail"},{"key":"R10-20251010","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1016\/j.jcmg.2022.03.019","article-title":"Reverse remodeling assessed by left atrial and ventricular strain reflects treatment response to sacubitril\/valsartan","volume":"15","author":"Moon","year":"2022","journal-title":"JACC Cardiovasc Imaging"},{"key":"R11-20251010","doi-asserted-by":"crossref","first-page":"e012272","DOI":"10.1161\/JAHA.119.012272","article-title":"Effects of the angiotensin-receptor neprilysin inhibitor on cardiac reverse remodeling: Meta-analysis","volume":"8","author":"Wang","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"R12-20251010","doi-asserted-by":"crossref","first-page":"754499","DOI":"10.3389\/fcvm.2021.754499","article-title":"Sacubitril-valsartan, clinical benefits and related mechanisms of action in heart failure with reduced ejection fraction. A review","volume":"8","author":"Pascual-Figal","year":"2021","journal-title":"Front Cardiovasc Med"},{"key":"R13-20251010","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1093\/ehjci\/jead196","article-title":"Phenotyping heart failure by echocardiography: Imaging of ventricular function and haemodynamics at rest and exercise","volume":"24","author":"Smiseth","year":"2023","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"R14-20251010","doi-asserted-by":"crossref","first-page":"5623","DOI":"10.3390\/jcm12175623","article-title":"Interrelationships between peak strain dispersion, myocardial work indices, isovolumetric relaxation and systolic-diastolic coupling in middle-aged healthy subjects","volume":"12","author":"Minczykowski","year":"2023","journal-title":"J Clin Med"},{"key":"R15-20251010","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1111\/echo.15071","article-title":"Persistence of abnormal global longitudinal strain in women with peripartum cardiomyopathy","volume":"38","author":"Bortnick","year":"2021","journal-title":"Echocardiography"},{"key":"R16-20251010","doi-asserted-by":"crossref","first-page":"214","DOI":"10.4103\/jcecho.jcecho_48_24","article-title":"Improving outcomes in peripartum cardiomyopathy with vericiguat: A clinical case","volume":"34","author":"Cacciapuoti","year":"2024","journal-title":"J Cardiovasc Echogr"},{"key":"R17-20251010","doi-asserted-by":"crossref","first-page":"114","DOI":"10.4103\/jcecho.jcecho_24_17","article-title":"Subsequent safe pregnancy with cesarean delivery in a patient with a history of peripartum Takotsubo syndrome complicated by cardiogenic shock","volume":"27","author":"Citro","year":"2017","journal-title":"J Cardiovasc Echogr"}],"container-title":["Journal of Cardiovascular Echography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_102_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:51:51Z","timestamp":1787068311000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_102_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":17,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jcecho.jcecho_102_24","relation":{},"ISSN":["2211-4122","2347-193X"],"issn-type":[{"value":"2211-4122","type":"print"},{"value":"2347-193X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"2024-12-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}