{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:23:28Z","timestamp":1787844208479,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>We present the case of a 48-year-old man referred for a reduced exercise tolerance in whom a bileaflet mitral prolapse (Barlow's disease), associated with flail motion of posterior mitral leaflet and ruptured chordae tendineae and complicated by eccentric severe regurgitation, was incidentally diagnosed. Albeit paucisymptomatic, at echocardiography he showed the signs of LV dysfunction and, accordingly, was underwent surgical mitral valvuloplasty with implantation of the Memo 3D ReChord Ring without complications. We analyzed the changes of echocardiographic parameters of cardiac remodeling from baseline to post operative setting, highlighting the utility of modern imaging tools (strain and myocardial work) in grade to gauge with more sensitivity LV deformation and function in different conditions of pre and afterload and to overcome the limits of ancient ejection fraction. In conclusion, especially LV myocardial work may be a promising and accurate non load dipendent tool to quantify subclinical LV dysfunction, to guide therapeutic decisions and in post-surgical follow up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcecho.jcecho_108_20","type":"journal-article","created":{"date-parts":[[2021,5,20]],"date-time":"2021-05-20T03:43:54Z","timestamp":1621482234000},"page":"48-50","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Cardiac Remodeling after Surgical Mitral Valvuloplasty for Barlow's Disease"],"prefix":"10.4103","volume":"31","author":[{"given":"Nicolino","family":"Esposito","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Vincenza","family":"Polito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Mattiello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Galderisi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20240904","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1136\/heartjnl-2017-311510","article-title":"Heartbeat: Afterload is high (not low) in chronic mitral regurgitation!","volume":"103","author":"Otto","year":"2017","journal-title":"Heart"},{"key":"R2-11-20240904","doi-asserted-by":"crossref","first-page":"2739","DOI":"10.1093\/eurheartj\/ehx391","article-title":"2017 ESC\/EACTS Guidelines for the management of valvular heart disease","volume":"38","author":"Baumgartner","year":"2017","journal-title":"Eur Heart J"},{"key":"R3-11-20240904","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.euje.2006.11.002","article-title":"Assessment of subclinical left ventricular dysfunction in asymptomatic mitral regurgitation","volume":"8","author":"Lee","year":"2007","journal-title":"Eur J Echocardiogr"},{"key":"R4-11-20240904","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1136\/heartjnl-2016-311009","article-title":"A tragedy of modern cardiology: Using ejection fraction to gauge left ventricular function in mitral regurgitation","volume":"103","author":"Carabello","year":"2017","journal-title":"Heart"},{"key":"R5-11-20240904","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1016\/j.jcmg.2018.03.016","article-title":"Myocardial Strain in Prediction of outcomes after surgery for severe mitral regurgitation","volume":"11","author":"Kim","year":"2018","journal-title":"JACC Cardiovasc Imaging"},{"key":"R6-11-20240904","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1136\/heartjnl-2016-310472","article-title":"How heavy is the load. The ventricular mechanics of mitral regurgitation revisited in the era of percutaneous therapies?","volume":"103","author":"Martinez-Legazpi","year":"2017","journal-title":"Heart"},{"key":"R7-11-20240904","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s12947-019-0178-7","article-title":"Global longitudinal strain is a hallmark of cardiac damage in mitral regurgitation: The Italian arm of the European Registry of mitral regurgitation (EuMiClip)","volume":"17","author":"Santoro","year":"2019","journal-title":"Cardiovasc Ultrasound"},{"key":"R8-11-20240904","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/j.athoracsur.2011.11.034","article-title":"Changes in left ventricular function after mitral valve repair for severe organic mitral regurgitation","volume":"93","author":"Witkowski","year":"2012","journal-title":"Ann Thorac Surg"},{"key":"R9-11-20240904","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1002\/clc.20201","article-title":"Paradoxical septal motion after cardiac surgery: A review of 3292 cases","volume":"30","author":"Reynolds","year":"2007","journal-title":"Clin Cardiol"},{"key":"R10-11-20240904","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1007\/s10741-019-09785-2","article-title":"Right ventricular function after cardiac surgery: The diagnostic and prognostic role of echocardiography","volume":"24","author":"Mandoli","year":"2019","journal-title":"Heart Fail Rev"}],"container-title":["Journal of Cardiovascular Echography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_108_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:14:22Z","timestamp":1787843662000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_108_20"}},"subtitle":["Is it the Time to Look to the Load?"],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jcecho.jcecho_108_20","relation":{},"ISSN":["2211-4122"],"issn-type":[{"value":"2211-4122","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}