{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:50Z","timestamp":1786650110347,"version":"build-2736575974"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>West Nile virus (WNV) has recently been described as a possible trigger of cardiovascular diseases (CVDs). There is little data in the literature about this association.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods:<\/jats:title>\n                    <jats:p>In the present meta-summary, eight case reports describing patients who experienced CVDs following a WNV infection were included. Patient characteristics, triggers, and type of syncope were collected.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of eight patients with a median age of 67.29 (interquartile range: 53\u201370) years were evaluated; 87.5% were male. Seventy-five percent of patients had an altered mental status. Left ventricular ejection fraction was impaired in five patients (62.5%). Four of eight patients (50%) had arrhythmias, with 3 of them having a normal ejection fraction. Sudden cardiac death was reported in one patient (12.5%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>CVDs due to WNV have been associated with myocarditis and arrhythmias, among elderly patients, males, and those with neurological impairment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcecho.jcecho_141_25","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T20:00:28Z","timestamp":1777406428000},"page":"33-37","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["West Nile Virus as a Trigger for Cardiovascular Diseases: A Meta-summary of Case Reports"],"prefix":"10.4103","volume":"36","author":[{"given":"Alfredo","family":"Mauriello","sequence":"first","affiliation":[{"name":"Division of Cardiology, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Correra","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Foggia, Foggia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Zumbo","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Giallauria","sequence":"additional","affiliation":[{"name":"Department of Translational Medical Sciences, University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfredo","family":"Caturano","sequence":"additional","affiliation":[{"name":"Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pierpaolo Di","family":"Micco","sequence":"additional","affiliation":[{"name":"Department of Medicina Medicina, UOC Medicina Interna, P.O. Santa Maria Delle Grazie, Pozzuoli, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonello","family":"D\u2019andrea","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Cardiology and Intensive Care Unit, \u201cUmberto I\u201d Hospital, Nocera, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alberto Enrico","family":"Maraolo","sequence":"additional","affiliation":[{"name":"Department of Clinical Medicine and Surgery, University of Naples \u201cFederico II\u201d, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Russo","sequence":"additional","affiliation":[{"name":"Department of Medical and Translational Sciences, Cardiology Unit, University of Campania \u201cLuigi Vanvitelli,\u201d Monaldi Hospital, Naples, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"R1-20260429","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-1-4939-3670-0_1","article-title":"A brief review of West Nile virus biology","volume":"1435","author":"Londono-Renteria","year":"2016","journal-title":"Methods Mol Biol"},{"key":"R2-20260429","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1038\/s41564-020-0714-0","article-title":"The continued threat of emerging flaviviruses","volume":"5","author":"Pierson","year":"2020","journal-title":"Nat Microbiol"},{"key":"R3-20260429","doi-asserted-by":"crossref","first-page":"E541","DOI":"10.1111\/1469-0691.12001","article-title":"Novel West Nile virus lineage 1a full genome sequences from human cases of infection in North-Eastern Italy, 2011","volume":"18","author":"Barzon","year":"2012","journal-title":"Clin Microbiol Infect"},{"key":"R4-20260429","doi-asserted-by":"crossref","first-page":"105132","DOI":"10.1016\/j.idnow.2025.105132","article-title":"West Nile virus in Italy: A rising public health concern calling for reinforced surveillance and preventive measures","volume":"55","author":"Ferrara","year":"2025","journal-title":"Infect Dis Now"},{"key":"R5-20260429","doi-asserted-by":"crossref","first-page":"360","DOI":"10.7326\/0003-4819-141-5-200409070-00010","article-title":"Clinical characteristics and functional outcomes of West Nile fever","volume":"141","author":"Watson","year":"2004","journal-title":"Ann Intern Med"},{"key":"R6-20260429","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1017\/S0950268818000687","article-title":"Morbidity, mortality and long-term sequelae of West Nile virus disease in Qu\u00e9bec","volume":"146","author":"Ouhoumanne","year":"2018","journal-title":"Epidemiol Infect"},{"key":"R7-20260429","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/eurjpc\/zwae384","article-title":"Temporal trend and attributable risk factors of cardiovascular disease burden for adults 55 years and older in 204 countries\/territories from 1990 to 2021: An analysis for the Global Burden of Disease Study 2021","volume":"32","author":"Wang","year":"2025","journal-title":"Eur J Prev Cardiol"},{"key":"R8-20260429","first-page":"e28473","article-title":"A rare case of West Nile virus-associated cardiomyopathy","volume":"14","author":"Gao","year":"2022","journal-title":"Cureus"},{"key":"R9-20260429","first-page":"8517728","article-title":"A rare case of cardiac recovery after acute myocarditis from West Nile virus infection: A review of the current literature","volume":"2022","author":"Lei","year":"2022","journal-title":"Case Rep Cardiol"},{"key":"R10-20260429","doi-asserted-by":"crossref","first-page":"7147","DOI":"10.1186\/1757-1626-2-7147","article-title":"West Nile virus myocarditis causing a fatal arrhythmia: A case report","volume":"2","author":"Kushawaha","year":"2009","journal-title":"Cases J"},{"key":"R11-20260429","first-page":"827","article-title":"West Nile virus and myocarditis, a rare event: Case report","volume":"24","author":"Laurito","year":"2023","journal-title":"G Ital Cardiol (Rome)"},{"key":"R12-20260429","first-page":"e3821","article-title":"Sinus bradycardia and QT interval prolongation in West Nile virus encephalitis: A case report","volume":"11","author":"Ajam","year":"2019","journal-title":"Cureus"},{"key":"R13-20260429","doi-asserted-by":"crossref","first-page":"2820","DOI":"10.1016\/S0735-1097(23)03264-3","article-title":"A case of neuroinvasive West Nile virus and sick sinus syndrome","volume":"81","author":"Oates","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"R14-20260429","doi-asserted-by":"crossref","first-page":"214","DOI":"10.4172\/2314-7326.1000214","article-title":"Idioventricular rhythm in a case of West Nile encephalomyelitis","volume":"7","author":"Espinosa","year":"2016","journal-title":"J Neuroinfect Dis"},{"key":"R15-20260429","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/SMJ.0b013e31819e9bf7","article-title":"Significant cardiomyopathy secondary to West Nile virus infection","volume":"102","author":"Khouzam","year":"2009","journal-title":"South Med J"},{"key":"R16-20260429","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement: An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"R17-20260429","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1136\/bmjebm-2017-110853","article-title":"Methodological quality and synthesis of case series and case reports","volume":"23","author":"Murad","year":"2018","journal-title":"BMJ Evid Based Med"},{"key":"R18-20260429","doi-asserted-by":"crossref","first-page":"e0200200","DOI":"10.1371\/journal.pone.0200200","article-title":"Prevalence of chronic comorbidities in dengue fever and West Nile virus: A systematic review and meta-analysis","volume":"13","author":"Badawi","year":"2018","journal-title":"PLoS One"},{"key":"R19-20260429","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1001\/jama.2013.8042","article-title":"West Nile virus: Review of the literature","volume":"310","author":"Petersen","year":"2013","journal-title":"JAMA"},{"key":"R20-20260429","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1086\/503038","article-title":"West Nile virus disease: A descriptive study of 228 patients hospitalized in a 4-county region of Colorado in 2003","volume":"42","author":"Bode","year":"2006","journal-title":"Clin Infect Dis"},{"key":"R21-20260429","doi-asserted-by":"crossref","first-page":"e19575","DOI":"10.1371\/journal.pone.0019575","article-title":"Autonomic nervous dysfunction in hamsters infected with West Nile virus","volume":"6","author":"Wang","year":"2011","journal-title":"PLoS One"},{"key":"R22-20260429","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1001\/jama.2025.8737","article-title":"West Nile virus: A review","volume":"334","author":"Gould","year":"2025","journal-title":"JAMA"}],"container-title":["Journal of Cardiovascular Echography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_141_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:02:54Z","timestamp":1786647774000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_141_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jcecho.jcecho_141_25","relation":{},"ISSN":["2211-4122","2347-193X"],"issn-type":[{"value":"2211-4122","type":"print"},{"value":"2347-193X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-10-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}