{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:29:51Z","timestamp":1786728591852,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,7]]},"abstract":"Abstract<\/jats:title>\n \n Background:<\/jats:title>\n One of the most common complications associated with dobutamine stress echocardiography (DSE) is abnormal blood pressure (BP) responses.<\/jats:p>\n <\/jats:sec>\n \n Aims and Objectives:<\/jats:title>\n The current investigation aimed to examine the blood pressure responses during DSE and its potential implications on cardiovascular outcomes.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n \n The study enrolled patients who lacked a history of hypertension and diabetes but demonstrated hypertensive response during DSE (\n n<\/jats:italic>\n = 62). An equal number of patients who did not exhibit an increase in BP during the DSE were selected as the control group (\n n<\/jats:italic>\n = 55). Throughout the 4-year clinical follow-up, we monitored the incidence of hypertension, myocardial infarction (MI), hospitalization due to heart disease, death, and stroke.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Among those who demonstrated a hypertensive response during DSE, baseline systolic BP (\n P<\/jats:italic>\n = 0.002) and diastolic BP (\n P<\/jats:italic>\n = 0.002) were notably higher compared to the nonhypertensive group. In addition, the hypertensive group received a significantly elevated dosage of dobutamine in comparison to the controls (\n P<\/jats:italic>\n = 0.010). However, no statistically significant variances were observed between the two groups concerning death (\n P<\/jats:italic>\n = 0.600), acute MI (\n P<\/jats:italic>\n > 0.999), chronic hypertension (\n P<\/jats:italic>\n = 0.063), diabetes mellitus (\n P<\/jats:italic>\n = 0.513), and hospitalization (\n P<\/jats:italic>\n = 0.472).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n In light of our findings, hypertensive responses in patients undergoing DSE do not correlate with subsequent adverse outcomes. While our investigation did not identify a statistically significant difference in hypertension rates, it is essential to note that significance may be achieved with future research involving a larger sample size.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jcecho.jcecho_16_25","type":"journal-article","created":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T05:00:18Z","timestamp":1759294818000},"page":"264-270","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Hypertensive Response During Dobutamine Stress Echocardiography: Does it Indicate a Higher Risk of Developing Hypertension?"],"prefix":"10.4103","volume":"35","author":[{"given":"Hedieh","family":"Alimi","sequence":"first","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, 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