{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:21:23Z","timestamp":1788182483178,"version":"build-2803163510"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T00:00:00Z","timestamp":1778025600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:p>We report the echocardiographic features of the first case of left bundle branch area pacing (LBBAP) in a woman with concurrent lamin and SCN5A mutations presenting with familial heart block. Left ventricular ejection fraction, global longitudinal strain, myocardial work, and septal-to-posterior activation pattern were conserved at 3 months postimplantation with excellent pacing parameters, demonstrating feasibility and short-term preservation of left ventricular mechanics of LBBAP in this very rare disease.<\/jats:p>","DOI":"10.4103\/jcecho.jcecho_19_26","type":"journal-article","created":{"date-parts":[[2026,5,7]],"date-time":"2026-05-07T09:02:14Z","timestamp":1778144534000},"page":"467-471","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Echocardiographic Features of Left Bundle Branch Area Pacing in a Patient with Concomitant Lamin and SCN5A Cardiomyopathy"],"prefix":"10.4103","volume":"36","author":[{"given":"Shing","family":"Ching","sequence":"first","affiliation":[{"name":"Department of Medicine and Geriatrics, Division of Cardiology, United Christian Hospital, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexson Tsz-Ki","family":"Lau","sequence":"additional","affiliation":[{"name":"Department of Medicine and Geriatrics, Division of Cardiology, United Christian Hospital, Hong Kong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5,6]]},"reference":[{"key":"R1-20260831","first-page":"2050313","article-title":"Atrial standstill associated with lamin A\/C mutation: A case report","volume":"11","author":"Zhang","year":"2023","journal-title":"SAGE Open Med Case Rep"},{"key":"R2-20260831","doi-asserted-by":"crossref","first-page":"euaf181","DOI":"10.1093\/europace\/euaf181","article-title":"Two-year outcomes of left bundle branch area pacing versus traditional right ventricular pacing in middle-aged adults: A registry-based trial","volume":"27","author":"Bertini","year":"2025","journal-title":"Europace"},{"key":"R3-20260831","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.hrthm.2024.10.038","article-title":"Global R-wave peak time for diagnosis of left bundle branch capture","volume":"22","author":"Kie\u0142basa","year":"2025","journal-title":"Heart Rhythm"},{"key":"R4-20260831","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1093\/europace\/euab164","article-title":"The V6-V1 interpeak interval: A novel criterion for the diagnosis of left bundle branch capture","volume":"24","author":"Jastrz\u0119bski","year":"2022","journal-title":"Europace"},{"key":"R5-20260831","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.jaccas.2020.11.046","article-title":"Sudden cardiac arrest in a patient with mitral valve prolapse and LMNA and SCN5A mutations","volume":"3","author":"Mahajan","year":"2021","journal-title":"JACC Case Rep"},{"key":"R6-20260831","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1016\/j.hrthm.2023.03.1538","article-title":"2023 HRS\/APHRS\/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure","volume":"20","author":"Chung","year":"2023","journal-title":"Heart Rhythm"},{"key":"R7-20260831","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.jacc.2023.05.006","article-title":"Comparison of left bundle branch area pacing and biventricular pacing in candidates for resynchronization therapy","volume":"82","author":"Vijayaraman","year":"2023","journal-title":"J Am Coll Cardiol"},{"key":"R8-20260831","doi-asserted-by":"crossref","first-page":"euaf050","DOI":"10.1093\/europace\/euaf050","article-title":"European Society of Cardiology (ESC) clinical consensus statement on indications for conduction system pacing, with special contribution of the European Heart Rhythm Association of the ESC and endorsed by the Asia Pacific Heart Rhythm Society, the Canadian Heart Rhythm Society, the Heart Rhythm Society, and the Latin American Heart Rhythm Society","volume":"27","author":"Glikson","year":"2025","journal-title":"Europace"},{"key":"R9-20260831","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1016\/j.jacep.2025.03.037","article-title":"Left ventricular mechanical insights into left bundle branch pacing and left ventricular septal pacing","volume":"11","author":"Bertini","year":"2025","journal-title":"JACC Clin Electrophysiol"},{"key":"R10-20260831","doi-asserted-by":"crossref","first-page":"99","DOI":"10.4103\/jcecho.jcecho_37_24","article-title":"Clinical applications of myocardial work in echocardiography: A comprehensive review","volume":"34","author":"Trimarchi","year":"2024","journal-title":"J Cardiovasc Echogr"},{"key":"R11-20260831","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.ijcard.2020.08.048","article-title":"Comparison of cardiac function between left bundle branch pacing and right ventricular outflow tract septal pacing in the short-term: A registered controlled clinical trial","volume":"322","author":"Liu","year":"2021","journal-title":"Int J Cardiol"},{"key":"R12-20260831","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1540-8175.1995.tb00556.x","article-title":"Preimplantation echo Doppler evaluation of VVI versus DDD pacing","volume":"12","author":"Soussou","year":"1995","journal-title":"Echocardiography"}],"container-title":["Journal of Cardiovascular Echography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_19_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T13:00:51Z","timestamp":1788181251000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_19_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,6]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jcecho.jcecho_19_26","relation":{},"ISSN":["2211-4122","2347-193X"],"issn-type":[{"value":"2211-4122","type":"print"},{"value":"2347-193X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,6]]},"assertion":[{"value":"2026-02-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}