{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:37:12Z","timestamp":1787071032095,"version":"build-2736575974"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"\n Context:<\/jats:title>\n Coronavirus disease 2019 (COVID-19) has been revealed as a severe illness with a wide-ranging cardiac manifestation and has a worldwide burden on the health-care system.<\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n Our aim in this study is to assess the impact of mild COVID-19 infection on cardiac function in patients without previous structural heart disease.<\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n We evaluated 100 outpatients with a history of mild COVID-19 infection without needing hospitalization within 3 weeks to 3 months after recovery from the acute phase of the illness between August 2020 and July 2021.<\/jats:p>\n <\/jats:sec>\n \n Subjects and Methods:<\/jats:title>\n The patients were compared with 105 healthy participants without a history of COVID-19 as the control group. All participants underwent comprehensive transthoracic echocardiography.<\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis Used:<\/jats:title>\n \n Data were analyzed using IBM SPSS statistics 23. For all tests,\n P<\/jats:italic>\n < 0.05 was defined as statistically significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n COVID-19 patients had higher global longitudinal strain (\n P<\/jats:italic>\n = 0.001), systolic pulmonary artery pressure (\n P<\/jats:italic>\n = 0.008), RV E\u2019 (\n P<\/jats:italic>\n = 0.049), and RV A\u2019 (\n P<\/jats:italic>\n = 0.003), while had lower septal tissue velocities (\n P<\/jats:italic>\n = 0.01) and left ventricular ejection fraction (EF) (LVEF) (\n P<\/jats:italic>\n = 0.03). Abnormal EF (LVEF <55%) was noted in 19% of the COVID-19 patients and 8.6% of the control group (\n P<\/jats:italic>\n = 0.03). Moderate or more diastolic dysfunction was noted in 10 COVID-19 patients but only in one participant in the control group (\n P<\/jats:italic>\n = 0.005).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Mild COVID-19 infection can result in cardiac functional and structural changes, even in patients without known previous structural heart disease. Echocardiography can be a useful modality for risk assessment and follow-up in patients with COVID-19.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jcecho.jcecho_3_24","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T06:27:42Z","timestamp":1719901662000},"page":"72-76","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Echocardiographic Assessment of Recovered Patients with Mild COVID-19 Infection: A Case\u2013Control Study"],"prefix":"10.4103","volume":"34","author":[{"given":"Hedieh","family":"Alimi","sequence":"first","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Bigdelu","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoorak","family":"Poorzand","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fereshteh","family":"Ghaderi","sequence":"additional","affiliation":[{"name":"Vascular and Endovascular Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Emadzadeh","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Faculty of Medicine, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asal","family":"Yadollahi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of 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