{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:32:41Z","timestamp":1787761961386,"version":"build-2784847793"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>\n                    Heart valve leaflet\u2019s aneurysm is a rare finding, and literature about this topic is sparse. Early recognition is important because their rupture can lead to catastrophic valve regurgitation. An 84-year-old male with chronic ischemic cardiomyopathy was admitted to the coronary intensive care unit for non-ST elevation myocardial infarction. Baseline transthoracic echocardiography showed normal biventricular function with inhomogeneous thickening of aortic leaflets with moderate aortic regurgitation. Because the acoustic window was limited, a transesophageal echocardiography was performed, detecting a small mass in the right aortic coronary cusp with moderate regurgitation (orifice regurgitation area: 0.54 cm\n                    <jats:sup>2<\/jats:sup>\n                    ; med\/max gradient: 16\/32 mmHg). Endocarditis was ruled out. Because of the rapid worsening of the patient\u2019s conditions, requiring mechanical ventilation and hemofiltration, and the potential hazard of an urgent coronary angiography, a cardiac computed tomographic angiography was performed. Detailed spatial reconstructions highlighted a bilobed cavitation in the aortic leaflets. Diagnosis of aortic leaflets\u2019 aneurysm was made. A \u201dwait and see\u201d strategy was chosen, and the patient\u2019s general conditions gradually improved and now he is stable and uneventful. To date, no aortic leaflet\u2019s aneurysm was described in literature.\n                  <\/jats:p>","DOI":"10.4103\/jcecho.jcecho_59_22","type":"journal-article","created":{"date-parts":[[2023,5,26]],"date-time":"2023-05-26T05:17:14Z","timestamp":1685078234000},"page":"30-32","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Unique Case of Aortic Valve Leaflet\u2019s Aneurysm Detected by Cardiac Computed Tomographic Angiography"],"prefix":"10.4103","volume":"33","author":[{"given":"Valeria","family":"Pergola","sequence":"first","affiliation":[{"name":"Department of Cardio-Thoraco-Vascular Sciences and Public Health, Cardiology Unit, University of Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulio","family":"Cabrelle","sequence":"additional","affiliation":[{"name":"Department of Medicine, DIMED, University of Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Motta","sequence":"additional","affiliation":[{"name":"Department of Medicine, DIMED, University of Padua, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,5,29]]},"reference":[{"key":"B1-20240904","doi-asserted-by":"crossref","first-page":"345","DOI":"10.14503\/THIJ-15-5322","article-title":"Infective endocarditis of the aortic valve with anterior mitral valve leaflet aneurysm","volume":"43","author":"Tomsic","year":"2016","journal-title":"Tex Heart Inst J"},{"key":"B2-20240904","first-page":"298","article-title":"Mitral valve aneurysm associated with aortic valve endocarditis and regurgitation","volume":"5","author":"Raval","year":"2002","journal-title":"Heart Surg Forum"},{"key":"B3-20240904","doi-asserted-by":"crossref","first-page":"690","DOI":"10.5543\/tkda.2011.01671","article-title":"A rare cause of severe mitral regurgitation: Mitral valve aneurysm","volume":"39","author":"G\u00fcler","year":"2011","journal-title":"Turk Kardiyol Dern Ars"},{"key":"B4-20240904","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.3390\/diagnostics11122305","article-title":"Challenging cases of aortic prosthesis dysfunction, the importance of multimodality imaging, a case series","volume":"11","author":"Pergola","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"Suppl 1","key":"B5-20240904","article-title":"Clinical and echocardiographic features of valvular aneurysms","volume":"23","author":"Galzerano","year":"2022","journal-title":"Eur Heart J Cardiovasc Imaging"},{"key":"B6-20240904","doi-asserted-by":"crossref","first-page":"4368","DOI":"10.1007\/s00330-018-5965-2","article-title":"The usefulness of cardiac CT in the diagnosis of perivalvular complications in patients with infective endocarditis","volume":"29","author":"Hryniewiecki","year":"2019","journal-title":"Eur Radiol"}],"container-title":["Journal of Cardiovascular Echography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_59_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:10:11Z","timestamp":1787760611000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_59_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/jcecho.jcecho_59_22","relation":{},"ISSN":["2211-4122","2347-193X"],"issn-type":[{"value":"2211-4122","type":"print"},{"value":"2347-193X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-09-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-02-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}