{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:59Z","timestamp":1786650119095,"version":"build-2736575974"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>Situs inversus totalis (SIT) is a rare congenital condition, characterized by complete mirror-image transposition of the thoracic and abdominal organs. Although individual reports of myocardial infarction (MI) or cerebrovascular accidents in patients with SIT exist, the simultaneous occurrence of both is extremely rare and poses unique diagnostic and therapeutic challenges. We report the case of a 55-year-old female presenting with right-sided chest pain and later developing neurological deficits. Initial evaluation revealed dextrocardia and SIT on chest radiograph and abdominal ultrasound. Electrocardiogram (ECG) showed ST-segment elevation in leads V1-V4, suggestive of anterior wall MI. The diagnosis was complicated due to reversed anatomical orientation. On day 3, the patient developed left-sided weakness and computed tomography of the brain confirmed an acute infarct in the right parietal lobe. Echocardiography revealed left ventricular apical clot with reduced ejection fraction. A coronary angiogram showed double-vessel disease involving the left anterior descending artery and ramus arteries and percutaneous coronary intervention was performed. This case highlights the clinical complexity and diagnostic uncertainty in managing cardiovascular and neurological events in patients with SIT. To our knowledge, this is one of the first reported cases of concomitant MI and stroke in a patient with SIT.<\/jats:p>","DOI":"10.4103\/jcecho.jcecho_94_25","type":"journal-article","created":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T20:00:21Z","timestamp":1777406421000},"page":"62-65","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A Rare Case Study of Dextrocardia with Myocardial Infarction and Cerebrovascular accident in Situs Inversus Totalis"],"prefix":"10.4103","volume":"36","author":[{"given":"Sanjay","family":"Thorat","sequence":"first","affiliation":[{"name":"Department of General Internal Medicine, Krishna Vishwa Vidyapeeth (Deemed to be University), Karad, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,28]]},"reference":[{"key":"R1-20260429","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.2147\/IJGM.S295444","article-title":"Situs inversus totalis: A clinical review","volume":"15","author":"Eitler","year":"2022","journal-title":"Int J Gen Med"},{"key":"R2-20260429","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/j.jaccas.2020.05.026","article-title":"Acute anterior myocardial infarction in a patient with dextrocardia and situs inversus: An unusual coexistence","volume":"2","author":"Celik","year":"2020","journal-title":"JACC Case Rep"},{"key":"R3-20260429","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1186\/s13256-015-0695-4","article-title":"The role of electrocardiogram in the diagnosis of dextrocardia with mirror image atrial arrangement and ventricular position in a young adult Nigerian in Ile-Ife: A case report","volume":"9","author":"Ogunlade","year":"2015","journal-title":"J Med Case Rep"},{"key":"R4-20260429","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/j.jelectrocard.2008.11.004","article-title":"Acute anteroseptal myocardial infarction in a patient with dextrocardia","volume":"42","author":"Alzand","year":"2009","journal-title":"J Electrocardiol"},{"key":"R5-20260429","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/j.jemermed.2020.03.020","article-title":"ST-elevation myocardial infarction in a patient having dextrocardia with situs inversus","volume":"58","author":"Elliott","year":"2020","journal-title":"J Emerg Med"},{"key":"R6-20260429","first-page":"267","article-title":"Primary PCI for acute myocardial infarction in a patient with situs inversus totalis and dextrocardia","volume":"23","author":"Jain","year":"2021","journal-title":"J Cardiol Cases"},{"key":"R7-20260429","doi-asserted-by":"crossref","first-page":"e36209","DOI":"10.1016\/j.heliyon.2024.e36209","article-title":"Coronary angiography in dextrocardia with situs inversus and acute myocardial infarction: A case report and literature review","volume":"10","author":"Lu","year":"2024","journal-title":"Heliyon"}],"container-title":["Journal of Cardiovascular Echography"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_94_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:02:59Z","timestamp":1786647779000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcecho.jcecho_94_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":7,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jcecho.jcecho_94_25","relation":{},"ISSN":["2211-4122","2347-193X"],"issn-type":[{"value":"2211-4122","type":"print"},{"value":"2347-193X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-08-01","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}