{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T12:31:28Z","timestamp":1763037088430},"reference-count":27,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec id=\"st1\"><jats:title>Context:<\/jats:title><jats:p>Ectopic neurohypophysis (EN) refers to an interrupted, nonvisualized, and thinned out pituitary stalk with ectopic location of the posterior pituitary gland. Concurrent extra-pituitary cerebral and extra-cranial anomalies have been rarely reported in patients of EN.<\/jats:p><\/jats:sec><jats:sec id=\"st2\"><jats:title>Aim:<\/jats:title><jats:p>The aim of this study was to evaluate the magnetic resonance imaging (MRI) findings of extra-pituitary cerebral anomalies in pediatric patients of EN.<\/jats:p><\/jats:sec><jats:sec id=\"st3\"><jats:title>Settings and Design:<\/jats:title><jats:p>A hospital-based cross-sectional study was conducted in a tertiary care center.<\/jats:p><\/jats:sec><jats:sec id=\"st4\"><jats:title>Subjects and Methods:<\/jats:title><jats:p>The study group comprised eight pediatric patients of EN associated with extra-pituitary cerebral or vascular anomalies. Clinical and biochemical assessment was done in all patients.<\/jats:p><\/jats:sec><jats:sec id=\"st5\"><jats:title>Results:<\/jats:title><jats:p>Out of the total eight patients with EN, MRI showed interrupted pituitary stalk in five patients (62.5%) and nonvisible pituitary stalk in three patients (37.5%). Ectopic posterior pituitary bright spot was demonstrated in median eminence in six patients (75%), faintly visualized in one patient (12.5%) and nonvisualized in another one patient. Statistical significant association was noted between pituitary gland height and patient's body height with the pituitary gland volume (<jats:italic>P<\/jats:italic>&lt; 0.001). Varied extra-pituitary cerebral anomalies encountered in our patients ranged from isolated anomalies such as optic nerve hypoplasia in three patients (37.5%), corpus callosum dysplasia in four patients (50%), agyria-pachygyria complex in two patients (25%), and intracranial vascular anomalies in two patients to syndromic association of tuberous sclerosis in one patient.<\/jats:p><\/jats:sec><jats:sec id=\"st6\"><jats:title>Conclusion:<\/jats:title><jats:p>Identifying and reporting of associated extra-pituitary cerebral anomalies in patients with EN are crucial in assessing the overall neurological outcome of such patients.<\/jats:p><\/jats:sec>","DOI":"10.4103\/jcis.jcis_23_17","type":"journal-article","created":{"date-parts":[[2017,5,22]],"date-time":"2017-05-22T05:31:11Z","timestamp":1495431071000},"page":"19","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Extra-pituitary Cerebral Anomalies in Pediatric Patients of Ectopic Neurohypophysis: An Uncommon Association"],"prefix":"10.25259","volume":"7","author":[{"given":"Deb K","family":"Boruah","sequence":"first","affiliation":[{"name":"Department of Radiodiagnosis, Assam Medical College, Dibrugarh, Assam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shantiranjan","family":"Sanyal","sequence":"additional","affiliation":[{"name":"Department of Radiology, Airedale General Hospital, West Yorkshire, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arjun","family":"Prakash","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Assam Medical College, Dibrugarh, Assam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sashidhar","family":"Achar","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Assam Medical College, Dibrugarh, Assam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajanikant R","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T","family":"Pravakaran","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Assam Medical College, Dibrugarh, Assam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dhaval D","family":"Dhingani","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Assam Medical College, Dibrugarh, Assam, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barun K","family":"Sarmah","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, Sikkim Manipal Institute of Medical Sciences, Sikkim, 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