{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,7]],"date-time":"2024-09-07T19:44:22Z","timestamp":1725738262886},"reference-count":10,"publisher":"Scientific Scholar","content-domain":{"domain":["clinicalimagingscience.org"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>We report the characteristic neuroimaging features of a rare metabolic leukodystrophy in an 8-year-old boy, born of consanguineous parenthood. The child presented with macrocrania, regression of milestones, and dystonia. The patient was referred for magnetic resonance imaging with a clinical diagnosis of postmeningitic hydrocephalus. Imaging revealed ventriculomegaly, diffuse brain atrophy, bilaterally symmetric widened sylvian fissure with temporal lobe hypoplasia, periventricular white-matter hyperintensities, and atrophy with hyperintensity in bilateral basal ganglia was also seen. These imaging features were signatory to arrive at a diagnosis of glutaric aciduria type 1. This disorder may mimic other neurological diseases such as postmeningitic hydrocephalus, which delays the diagnosis. Since early diagnosis and treatment can arrest progression, increased awareness about this condition among radiologists will certainly prevent erroneous diagnosis as had occurred in our patient.<\/jats:p>","DOI":"10.4103\/jcis.jcis_56_18","type":"journal-article","created":{"date-parts":[[2018,11,15]],"date-time":"2018-11-15T09:21:55Z","timestamp":1542273715000},"page":"50","update-policy":"http:\/\/dx.doi.org\/10.25259\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["A Case of Mistaken Identity: Glutaric Aciduria Type I Masquerading as Postmeningitic Hydrocephalus"],"prefix":"10.25259","volume":"8","author":[{"given":"Heena","family":"Rajani","sequence":"first","affiliation":[{"name":"Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shabnam Bhandari","family":"Grover","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neha","family":"Antil","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amit","family":"Katyan","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"10894","published-online":{"date-parts":[[2018,11,15]]},"reference":[{"key":"10.4103\/jcis.JCIS_56_18\/ref-1","first-page":"966","article-title":"Glutaric aciduria type 1: MR findings in two cases","volume":"12","author":"Altman","year":"1991","journal-title":"AJNR Am J Neuroradiol"},{"key":"10.4103\/jcis.JCIS_56_18\/ref-2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1177\/197140091302600204","article-title":"Brain MRI findings as an important diagnostic clue in glutaric aciduria type 1","volume":"26","author":"Nunes","year":"2013","journal-title":"Neuroradiol J"},{"key":"10.4103\/jcis.JCIS_56_18\/ref-3","first-page":"976","volume-title":"Inherited metabolic disorders. 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