{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:26Z","timestamp":1787070926408,"version":"build-2736575974"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Low-grade appendiceal mucinous neoplasms (LAMNs) are benign non-invasive epithelial proliferations of the appendix. These usually present clinically as mucoceles and these rarely exceed 2 cm in diameter. Lesions confined to the lumen are labelled as LAMN; however those in which mucin spreads outside the peritoneum are labeled as pseudomyxoma peritonei (PMP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims and Objective:<\/jats:title>\n                    <jats:p>A retrospective study was conducted over a period of three years and all cases of appendectomies were studied. Twelve cases of LAMN were identified, which is a diagnostic dilemma for the pathologists and clinicians.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>LAMN was identified based on the histopathological features. Out of the 12 cases, 9 were classified as LAMN and 3 as appendiceal neoplasm with PMP. There was villous or flat proliferation of epithelial lining, loss lymphoid aggregates, and dissecting mucin within muscularis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>LAMNs are rare neoplasms of the appendix, with clinical presentation similar to acute appendicitis. Mucinous collections within the appendiceal wall should be extensively searched for mucosal changes and, if found, should prompt a careful search for pushing invasion of LAMNs. A thorough and vigilant gross examination can be of great help. Appendicectomy is the treatment of benign and grossly intact mucinous neoplasm.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcrt.jcrt_149_22","type":"journal-article","created":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T01:00:26Z","timestamp":1695258026000},"page":"840-843","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Low-grade appendiceal mucinous neoplasms: Histomorphological spectrum in a tertiary care hospital"],"prefix":"10.4103","volume":"20","author":[{"given":"Manisha","family":"Ahuja","sequence":"first","affiliation":[{"name":"Department of Pathology and Pediatric Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shramana","family":"Mandal","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pediatric Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Varuna","family":"Mallya","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pediatric Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meeta","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pediatric Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nita","family":"Khurana","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pediatric Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawanindra","family":"Lal","sequence":"additional","affiliation":[{"name":"Department of Pathology and Pediatric Surgery, Maulana Azad Medical College and Associated Hospitals, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,9,21]]},"reference":[{"key":"R1-20241021","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1007\/s13193-020-01147-x","article-title":"Local protocol for management of low-grade appendiceal mucinous neoplasm (LAMN)","volume":"11","author":"Boshnaq","year":"2020","journal-title":"Indian J Surg Oncol"},{"key":"R2-20241021","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1634\/theoncologist.2017-0081erratum","article-title":"Appendiceal mucinous neoplasms: Diagnosis and management","volume":"23","author":"Shaib","year":"2018","journal-title":"Oncologist"},{"key":"R3-20241021","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/PAS.0000000000000535","article-title":"Aconsensus for classification and pathologic reporting of pseudomyxoma peritonei and associated appendiceal neoplasia: The results 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Surg"}],"container-title":["Journal of Cancer Research and 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