{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:35:20Z","timestamp":1787070920519,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"Suppl 2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Synchronous primary cancers are very rare. Due to their low incidence rate and insidious onset, they may be easily overlooked or misdiagnosed. In addition, there is currently no international consensus for their clinical diagnosis and treatment. Three exceedingly unusual synchronous primary malignancies, carcinoma gallbladder with renal cell carcinoma, carcinoma gallbladder with carcinoma colon, and carcinoma gallbladder with carcinoma breast, are presented here. Together with their clinical presentation, therapeutic options and outcomes are also presented. Curative radical surgery of each particular tumor, along with postoperative chemotherapy or radiotherapy improves disease-free survival.<\/jats:p>","DOI":"10.4103\/jcrt.jcrt_976_22","type":"journal-article","created":{"date-parts":[[2024,2,21]],"date-time":"2024-02-21T03:07:44Z","timestamp":1708484864000},"page":"S958-S962","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["An unusual case series of synchronous primary malignancies: Carcinoma gallbladder with renal cell carcinoma, carcinoma gallbladder with carcinoma colon, carcinoma gallbladder with carcinoma breast"],"prefix":"10.4103","volume":"19","author":[{"given":"Sashibhusan","family":"Dash","sequence":"first","affiliation":[{"name":"Division of Molecular Epidemiology and Public Health, ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India"},{"name":"Department of Oncopathology, Acharya Harihar Post Graduate Institute of Cancer, Cuttack, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subrat K.","family":"Samantara","sequence":"additional","affiliation":[{"name":"Department of Surgical Oncology, Acharya Harihar Post Graduate Institute of Cancer, Cuttack, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krushna C.","family":"Pani","sequence":"additional","affiliation":[{"name":"Department of Oncopathology, Acharya Harihar Post Graduate Institute of Cancer, Cuttack, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manoranjan","family":"Ranjit","sequence":"additional","affiliation":[{"name":"Division of Molecular Epidemiology and Public Health, ICMR-Regional Medical Research Centre, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,4,30]]},"reference":[{"key":"R1-20241021","first-page":"1358","article-title":"Multiple primary malignant tumors: A 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stones","volume":"39","author":"Johansen","year":"1996","journal-title":"Gut"},{"key":"R11-20241021","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1007\/s12262-016-1524-8","article-title":"Synchronous breast cancer and gallbladder diseases-A chromosomal analysis: A pilot study at a tertiary care centre","volume":"79","author":"Chaudhary","year":"2017","journal-title":"Indian J Surg"},{"key":"R12-20241021","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1038\/gim.2015.166","article-title":"Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing","volume":"18","author":"Susswein","year":"2016","journal-title":"Genet Med"},{"key":"R13-20241021","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1159\/000490658","article-title":"Simultaneous resection for synchronous double primary cancers of the pancreas and the 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