{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:27:29Z","timestamp":1787772449134,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Spondylodiscitis (SD) is an inflammatory condition affecting the intervertebral discs and adjacent structures, often leading to serious complications, including epidural abscesses. This study aimed to differentiate postoperative SD from spontaneous cases caused by osteoporotic defects and associated pathologies, evaluating the frequency of SD in spinal diseases at a single center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A retrospective observational study involving 25 patients was conducted, analyzing variations between postoperative revisions in SD patients and spontaneous SD due to concurrent pathology and osteoporotic defects. The effects of postoperative wound healing following transforaminal lumbar interbody fusion and decompressive hemilaminectomy with pedicle screws were also investigated. Ethical guidelines were strictly followed during the study, conducted from January 2023 to September 2023 at Moscow City Clinical Hospital No. 68, Demikhova V.P.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among the 25 patients with spontaneous SD, 15 females and 10 males were included, with only two undergoing surgical revision. Predominant purulent inflammatory foci were observed at specific spinal levels, and demographics revealed prevalent comorbidities such as arterial hypertension (80%) and type 2 diabetes mellitus (60%). Postoperative complications included paravertebral abscesses and wound-related issues. Structural observations indicated vertebral destruction, joint gaps, and localized spinal canal narrowing, revealing complexities in SD cases.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Surgical intervention remains crucial for addressing SD-related vertebral complications, while antimicrobial therapy tailored to specific pathogens is pivotal. Concurrent conditions necessitate comprehensive management, often involving cardiological interventions. Postoperatively, a combined approach of conservative therapy and calcium phosphate adjuncts is recommended, especially considering the observed low bone density, aiming to optimize patient recovery and spinal stability.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcvjs.jcvjs_164_23","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T15:03:32Z","timestamp":1716563012000},"page":"185-189","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Spondylodiscitis: Understanding pathophysiology, surgical strategies, and postoperative management \u2013 A single-center study"],"prefix":"10.4103","volume":"15","author":[{"given":"Daniel","family":"Encarnaci\u00f3n-Santos","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, People of Friendship University RUDN, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim-A","family":"Valerievich","sequence":"additional","affiliation":[{"name":"Deparment of Neurosurgery, City Clinical Hospital \u2116 68 Gbuz Gkb Im. V.P. Demikhova, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gianluca","family":"Scalia","sequence":"additional","affiliation":[{"name":"Department of Head and Neck Surgery, Neurosurgery Unit, Garibaldi, Hospital, Catania, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eugeny","family":"Shestov","sequence":"additional","affiliation":[{"name":"Deparment of Neurosurgery, City Clinical Hospital \u2116 68 Gbuz Gkb Im. V.P. Demikhova, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Pachev","sequence":"additional","affiliation":[{"name":"Deparment of Neurosurgery, City Clinical Hospital \u2116 68 Gbuz Gkb Im. V.P. Demikhova, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack","family":"Wellington","sequence":"additional","affiliation":[{"name":"London School of Hygiene and Tropical Medicine, Branford Teaching Hospitals NHS Foundation Trust, Bradford, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Bozkurt","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Medical Park Ankara Hospital, Ankara, Turkey"},{"name":"Department of Neurosurgery, School of Medicine, Yuksek Ihtisas University, Ankara, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitriy","family":"Rubenovich-Chikara","sequence":"additional","affiliation":[{"name":"Deparment of Neurosurgery, City Clinical Hospital \u2116 68 Gbuz Gkb Im. V.P. Demikhova, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Kirilin","sequence":"additional","affiliation":[{"name":"Deparment of Neurosurgery, City Clinical Hospital \u2116 68 Gbuz Gkb Im. V.P. Demikhova, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gennady","family":"Chmutin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, People of Friendship University RUDN, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel","family":"Tapia","sequence":"additional","affiliation":[{"name":"Deparment of Orthopedic, Hospital Dr. Dario Contreras Santo Domingo, Santo Domingo Este, Dominican Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naim","family":"Ekhsan","sequence":"additional","affiliation":[{"name":"Deparment of Neurosurgery, City Clinical Hospital \u2116 68 Gbuz Gkb Im. V.P. Demikhova, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bipin","family":"Chaurasia","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Bhawani Hospital and Research Center, Birgunj, Nepal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,5,24]]},"reference":[{"key":"R1-20240904","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/s00117-021-00814-6","article-title":"Spondylodiscitis and epidural abscesses","volume":"61","author":"Rotzinger","year":"2021","journal-title":"Radiologe"},{"key":"R2-20240904","first-page":"875","article-title":"Spondylodiscitis:Diagnosis and treatment options","volume":"114","author":"Herren","year":"2017","journal-title":"Dtsch Arztebl Int"},{"key":"R3-20240904","first-page":"117","article-title":"Asystematic review:Characteristics, complications and treatment of spondylodiscitis","volume":"23","author":"Gentile","year":"2019","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"Suppl 3","key":"R4-20240904","first-page":"i11","article-title":"Spondylodiscitis:Update on diagnosis and management","volume":"65","author":"Gouliouris","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"R5-20240904","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1186\/s13018-019-1134-9","article-title":"SponDT (spondylodiscitis diagnosis and treatment):Spondylodiscitis scoring system","volume":"14","author":"Homagk","year":"2019","journal-title":"J Orthop Surg Res"},{"key":"R6-20240904","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1308\/rcsann.2015.0009","article-title":"Management of adult spontaneous spondylodiscitis and its rising incidence","volume":"97","author":"Sur","year":"2015","journal-title":"Ann R Coll Surg Engl"},{"key":"R7-20240904","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1186\/s12879-018-3377-1","article-title":"Appropriate duration of post-surgical intravenous antibiotic therapy for pyogenic spondylodiscitis","volume":"18","author":"Li","year":"2018","journal-title":"BMC Infect Dis"},{"key":"R8-20240904","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1007\/s00586-015-4318-y","article-title":"Outcome of conservative and surgical treatment of pyogenic spondylodiscitis:A systematic literature review","volume":"25","author":"Rutges","year":"2016","journal-title":"Eur Spine J"},{"key":"R9-20240904","first-page":"83","article-title":"Surgical approach algorithm in the treatment of lumbar and thoracolumbar pyogenic spondylodiscitis","volume":"32","author":"Akgul","year":"2022","journal-title":"Turk Neurosurg"},{"key":"R10-20240904","first-page":"513","article-title":"Management of postoperative spondylodiscitis with and without internal fixation","volume":"25","author":"Wang","year":"2015","journal-title":"Turk Neurosurg"}],"container-title":["Journal of Craniovertebral Junction and Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jcvjs.jcvjs_164_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:47:23Z","timestamp":1787770043000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jcvjs.jcvjs_164_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jcvjs.jcvjs_164_23","relation":{},"ISSN":["0974-8237","0976-9285"],"issn-type":[{"value":"0974-8237","type":"print"},{"value":"0976-9285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"2023-11-22","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}