{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:22:12Z","timestamp":1787764932577,"version":"build-2784847793"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Schwannomas of the first and second nerve roots are rare neurosurgical entities, harboring specific surgical features that make surgical resection particularly challenging and deserve specifics dissertations. This study is a retrospectively analysis of 14 patients operated in two different neurosurgical centers: the San Filippo Neri Hospital of Rome and the Federal Centre of Neurosurgery of Tjumen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>In the last 6 years, 14 patients underwent neurosurgical resection of high cervical (C1\u2013C2) schwannomas, in two different neurosurgical centers. Patients data regarding clinical presentation, radiological findings, and surgical results were retrospectively analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age was 50 years (range 13\u201374), the follow-up mean duration was 30 \u00b1 8.5 (range 24\u201372 months), and there was no significant differences among different tumor locations (intradural, extradural, and dumbbell). Surgical results were excellent: gross total resection was achieved in all cases and there were no intraoperative complications or postoperative mortality. All patients presented postoperative clinical improvement except one who remained stable. Karnofsky performance status, at the last follow-up, confirmed a global clinical improvement. No vertebral artery (VA) injury neither spinal instability occurred; nerve root sacrifice was reported in one case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Neurosurgical treatment of C1\u2013C2 schwannomas is associated with good outcomes in terms of extent of resection and neurological function. In particular, dumbbell shape and VA involvement do not represent limitations to achieve complete tumor resection and good clinical outcome. In conclusion, microsurgery represents the treatment of choice for C1\u2013C2 schwannomas.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcvjs.jcvjs_75_23","type":"journal-article","created":{"date-parts":[[2023,11,29]],"date-time":"2023-11-29T00:00:58Z","timestamp":1701216058000},"page":"426-432","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":7,"title":["Surgical management of spinal schwannomas arising from the first and second cervical roots: Results of a cumulative case series"],"prefix":"10.4103","volume":"14","author":[{"given":"Francesco","family":"Corrivetti","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy"},{"name":"Laboratory of Neuroanatomy, EBRIS Foundation, Salerno, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaelino","family":"Roperto","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinat","family":"Sufianov","sequence":"additional","affiliation":[{"name":"Federal Centre of Neurosurgery, Tyumen, Russia"},{"name":"Department of Neurosurgery, The State Education Institution of Higher Professional Training, The First Sechenov Moscow State Medical University Under Ministry of Health, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guglielmo","family":"Cacciotti","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arslan","family":"Musin","sequence":"additional","affiliation":[{"name":"Federal Centre of Neurosurgery, Tyumen, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert","family":"Sufianov","sequence":"additional","affiliation":[{"name":"Federal Centre of Neurosurgery, Tyumen, Russia"},{"name":"Department of Neurosurgery, The State Education Institution of Higher Professional Training, The First Sechenov Moscow State Medical University Under Ministry of Health, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"Mastronardi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, San Filippo Neri Hospital, ASL Roma 1, Rome, Italy"},{"name":"Department of Neurosurgery, The State Education Institution of Higher Professional Training, The First Sechenov Moscow State Medical University Under Ministry of Health, Moscow, Russia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,11,29]]},"reference":[{"key":"R1-20240904","doi-asserted-by":"crossref","first-page":"2019","DOI":"10.1007\/s00586-012-2345-5","article-title":"Primary spinal cord tumors: Review of 678 surgically treated patients in Japan. 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