{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:58:28Z","timestamp":1785214708914,"version":"3.55.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Context:<\/jats:title>\n                    <jats:p>Psychiatric comorbidity has been associated with worse perioperative outcomes and greater healthcare utilization after spine surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>This study compared complications and healthcare utilization among posterior cervical decompression and fusion (PCDF) patients with depression, psychotic disorders, or no mental-health diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>Retrospective cohort analysis of the National Inpatient Sample from 2016 to 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>The database was queried for elective adult PCDF encounters. Mental-health exposures were defined using Elixhauser indicators for depression and psychoses. Outcomes included medical complications, non-routine discharge, inpatient mortality, length of stay (LOS), and costs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis Used:<\/jats:title>\n                    <jats:p>\n                      Chi-square and multivariate logistic regression analyses were performed. Significance was set at the\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05 level.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      We identified 167,480 weighted admissions: 129,205 with no mental-health diagnosis, 32,500 with depression, and 5,775 with psychotic disorders. Depression was associated with higher odds of cardiovascular complications (odds ratio [OR]: 1.20,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), mechanical complications (OR: 1.24,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), a composite adverse-event outcome (OR: 1.17,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), and nonroutine discharge (OR: 1.12,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Psychotic disorders were associated with higher odds of mechanical complications (OR: 1.44,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.002), nonroutine discharge (OR: 1.32,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), and inpatient mortality (OR: 2.33,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.043). Costs were higher with depression and highest with psychotic disorders ($39,564 vs. $40,787 vs. $42,362;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). LOS was higher with depression and highest with psychotic disorders (4.10 vs. 4.36 vs. 4.81 days;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Depression and psychotic disorders are common in PCDF and are linked to worse outcomes and higher resource use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jcvjs.jcvjs_95_26","type":"journal-article","created":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T12:00:28Z","timestamp":1784894428000},"page":"434-440","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Depression and psychotic disorders elevate inpatient burden after posterior cervical decompression and fusion: Prioritizing screening and targeted discharge planning"],"prefix":"10.4103","volume":"17","author":[{"given":"Leonidas E.","family":"Mastrokostas","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"},{"name":"Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul G.","family":"Mastrokostas","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Yusupov","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abigail","family":"Razi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA"},{"name":"Department of Orthopaedic Surgery, Donald and Barbara Zucker School of Medicine, Hempstead, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron B.","family":"Lavi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke B.","family":"Schwartz","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Inzerillo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed","family":"Said","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Kucherina","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pemla","family":"Jagtiani","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Cooper University Health Care, Camden, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arie","family":"Monas","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John K.","family":"Houten","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Mount Sinai School of Medicine, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher K.","family":"Kepler","sequence":"additional","affiliation":[{"name":"Rothman Orthopaedic Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jad Bou","family":"Monsef","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, SUNY Downstate Health Sciences University, Brooklyn, USA"},{"name":"Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afshin E.","family":"Razi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Maimonides Medical Center, Brooklyn, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitchell K.","family":"Ng","sequence":"additional","affiliation":[{"name":"Rothman Orthopaedic Institute, Thomas Jefferson University Hospital, Philadelphia, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,7,24]]},"reference":[{"key":"R1-20260728","first-page":"43","article-title":"Degenerative cervical myelopathy: A clinical review","volume":"91","author":"Gibson","year":"2018","journal-title":"Yale J Biol Med"},{"key":"R2-20260728","doi-asserted-by":"crossref","first-page":"70S","DOI":"10.1177\/2192568217701914","article-title":"A clinical practice guideline for the management of patients with degenerative cervical myelopathy: Recommendations for patients with mild, moderate, and severe disease and nonmyelopathic patients with evidence of cord compression","volume":"7","author":"Fehlings","year":"2017","journal-title":"Global Spine J"},{"key":"R3-20260728","doi-asserted-by":"crossref","first-page":"e112","DOI":"10.1016\/j.wneu.2019.09.132","article-title":"Comparison of the inpatient complications and health care costs of anterior versus posterior cervical decompression and fusion in patients with multilevel degenerative cervical myelopathy: A retrospective propensity score-matched analysis","volume":"134","author":"Badhiwala","year":"2020","journal-title":"World Neurosurg"},{"key":"R4-20260728","doi-asserted-by":"crossref","first-page":"E111","DOI":"10.1097\/BRS.0000000000000064","article-title":"Psychiatric disorders and major spine surgery: Epidemiology and perioperative outcomes","volume":"39","author":"Menendez","year":"2014","journal-title":"Spine (Phila Pa 1976)"},{"key":"R5-20260728","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1016\/j.spinee.2020.03.004","article-title":"Are preoperative depression and anxiety associated with patient-reported outcomes, health care payments, and opioid use after anterior discectomy and fusion?","volume":"20","author":"Harris","year":"2020","journal-title":"Spine J"},{"key":"R6-20260728","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1177\/21925682211026913","article-title":"Presence and severity of mental illness is associated with increased risk of postoperative emergency visits, readmission, and reoperation following outpatient ACDF: A national database analysis","volume":"13","author":"Kamalapathy","year":"2023","journal-title":"Global Spine J"},{"key":"R7-20260728","doi-asserted-by":"crossref","first-page":"3247","DOI":"10.3390\/jcm13113247","article-title":"Impact of depression on postoperative medical and surgical outcomes in spine surgeries: A systematic review and meta-analysis","volume":"13","author":"Aghajanian","year":"2024","journal-title":"J Clin Med"},{"key":"R8-20260728","doi-asserted-by":"crossref","first-page":"741","DOI":"10.3171\/2023.12.SPINE23860","article-title":"The impact of anxiety and depression on lumbar spine surgical outcomes: A Michigan spine surgery improvement collaborative study","volume":"40","author":"Deshpande","year":"2024","journal-title":"J Neurosurg Spine"},{"key":"R9-20260728","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1016\/j.wneu.2024.09.010","article-title":"Correlations between psychiatric disorders and perioperative outcomes after lumbar fusions: An analysis of the national inpatient sample (2009-2020)","volume":"192","author":"Malueg","year":"2024","journal-title":"World Neurosurg"},{"key":"R10-20260728","doi-asserted-by":"crossref","first-page":"177","DOI":"10.3171\/2016.7.SPINE16472","article-title":"Preoperative mental health status may not be predictive of improvements in patient-reported outcomes following an anterior cervical discectomy and fusion","volume":"26","author":"Mayo","year":"2017","journal-title":"J Neurosurg Spine"},{"key":"R11-20260728","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.wneu.2015.11.067","article-title":"Pretreatment of depression before cervical spine surgery improves patients'perception of postoperative health status: A retrospective, single institutional experience","volume":"87","author":"Elsamadicy","year":"2016","journal-title":"World Neurosurg"},{"key":"R12-20260728","doi-asserted-by":"crossref","first-page":"e0258517","DOI":"10.1371\/journal.pone.0258517","article-title":"Anational snapshot of the impact of clinical depression on post-surgical pain and adverse outcomes after anterior cervical discectomy and fusion for cervical myelopathy and radiculopathy: 10-year results from the US nationwide inpatient sample","volume":"16","author":"Chen","year":"2021","journal-title":"PLoS One"},{"key":"R13-20260728","doi-asserted-by":"crossref","first-page":"2438","DOI":"10.1007\/s00586-025-08815-y","article-title":"Patients on antidepressants are more likely to be discharged to inpatient rehabilitation after lumbar fusion","volume":"34","author":"Dalton","year":"2025","journal-title":"Eur Spine J"},{"key":"R15-20260728","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1097\/BRS.0000000000004371","article-title":"Depression increases posterior cervical decompression and fusion revision rates and diminishes neck disability index improvement","volume":"47","author":"Toci","year":"2022","journal-title":"Spine (Phila Pa 1976)"},{"key":"R16-20260728","doi-asserted-by":"crossref","first-page":"2767","DOI":"10.1177\/21925682251316245","article-title":"Influence of preoperative depression on cervical spine surgery outcomes: A systematic review and meta-analysis","volume":"15","author":"Javeed","year":"2025","journal-title":"Global Spine J"},{"key":"R17-20260728","doi-asserted-by":"crossref","first-page":"11","DOI":"10.3171\/2023.2.SPINE22685","article-title":"Do comorbid self-reported depression and anxiety influence outcomes following surgery for cervical spondylotic myelopathy?","volume":"39","author":"Chan","year":"2023","journal-title":"J Neurosurg Spine"},{"key":"R18-20260728","doi-asserted-by":"crossref","first-page":"E472","DOI":"10.1097\/BSD.0000000000000957","article-title":"The impact of multiple comorbid mental health disorders on health-related quality of life following ACDF","volume":"33","author":"Mangan","year":"2020","journal-title":"Clin Spine Surg"},{"key":"R19-20260728","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.1097\/BRS.0000000000002651","article-title":"The impact of comorbid mental health disorders on complications following cervical spine surgery with minimum 2-year surveillance","volume":"43","author":"Diebo","year":"2018","journal-title":"Spine (Phila Pa 1976)"},{"key":"R20-20260728","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.jor.2017.08.006","article-title":"Effect of mental health on post-operative infection rates following cervical spine fusion procedures","volume":"14","author":"Dedeogullari","year":"2017","journal-title":"J Orthop"},{"key":"R21-20260728","first-page":"e24.00204","article-title":"Preoperative anxiety: An important risk factor of postoperative adverse events and increased reoperation rates in patients undergoing single-level anterior cervical diskectomy and fusion","volume":"8","author":"Katsnelson","year":"2024","journal-title":"J Am Acad Orthop Surg Glob Res Rev"},{"key":"R22-20260728","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/BRS.0000000000003222","article-title":"The impact of preoperative depression on hospital consumer assessment of healthcare providers and systems survey results in a cervical spine surgery setting","volume":"45","author":"Levin","year":"2020","journal-title":"Spine (Phila Pa 1976)"},{"key":"R23-20260728","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1097\/BRS.0b013e3182a0d507","article-title":"Incidence and risk factors for postoperative delirium after lumbar spine surgery","volume":"38","author":"Fineberg","year":"2013","journal-title":"Spine (Phila Pa 1976)"},{"key":"R24-20260728","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3928\/01477447-20230922-03","article-title":"Influence of anxiety and depression on opioid use after cervical spine fusion: An analysis of a national claims database","volume":"47","author":"Makanji","year":"2024","journal-title":"Orthopedics"}],"container-title":["Journal of Craniovertebral Junction and Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.4103\/jcvjs.jcvjs_95_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T04:00:24Z","timestamp":1785211224000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.4103\/jcvjs.jcvjs_95_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jcvjs.jcvjs_95_26","relation":{},"ISSN":["0974-8237","0976-9285"],"issn-type":[{"value":"0974-8237","type":"print"},{"value":"0976-9285","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"2026-04-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-24","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}