{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:25:11Z","timestamp":1787840711267,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n BACKGROUND:<\/jats:title>\n Clinical evaluations are not sufficient to adequately characterize the morbidity associated with hemophilia. Quality of life (QoL) of hemophilics and associated factors is not well explored in Indian research. The present study aimed to measure the QoL in hemophilics and its association with socio-demographic characteristics and other characteristics.<\/jats:p>\n <\/jats:sec>\n \n MATERIALS AND METHODS:<\/jats:title>\n \n A cross-sectional study was conducted during June\u2013November 2018. Two hundred and one hemophilics (age \u2265 4 years) were interviewed with a pre-tested schedule for sociodemographic and other relevant variables. QoL was measured by Haemo-QoL questionnaire for different pediatric age groups and Haem-A-QoL questionnaire for adults and assigned health-related QoL scores. Score achieved in each dimension as well as total scores were transformed on scales ranging from 0 to 100, high values indicate high impairment of QoL. Hemophilic arthropathy was assessed using the World Federation of Hemophilia Joint Scores. One-way ANOVA, independent\n t<\/jats:italic>\n -test, Kruskal\u2013Wallis test, and Spearman correlation analyses were performed using SPSS version 16.\n <\/jats:p>\n <\/jats:sec>\n \n RESULTS:<\/jats:title>\n Mean Haemo-QoL scores for 4\u20137 years, 8\u201312 years, 13\u201316 years, and >16 years were 43.92 \u00b1 8.09, 37.37 \u00b1 8.62, 32.79 \u00b1 6.66, and 45.92 \u00b1 6.30, respectively. Significant difference was noted for QoL scores across different age groups, grades of severity, educational, occupational categories, socioeconomic status classes, marital status, and presence or absence of target joint. Total QoL scores, as well as scores in some of the dimensions, showed a significant positive correlation with the World Federation of Hemophilia joint scores by Spearman correlation analysis.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS:<\/jats:title>\n Improvement of the joint health status by regular physiotherapy is needed to improve the QoL of hemophilics.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jehp.jehp_249_19","type":"journal-article","created":{"date-parts":[[2024,5,18]],"date-time":"2024-05-18T13:13:34Z","timestamp":1716038014000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":17,"title":["Health-related quality of life of hemophilics and its possible correlates: A perspective in health promotion and disability prevention"],"prefix":"10.4103","volume":"8","author":[{"given":"Soumyaneel","family":"Das","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Burdwan Medical College, Purba Bardhaman, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabindra Nath","family":"Roy","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Burdwan Medical College, Purba Bardhaman, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dilip Kumar","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Burdwan Medical College, Purba Bardhaman, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amitava","family":"Chakraborty","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Burdwan Medical College, Purba Bardhaman, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raston","family":"Mondal","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Burdwan Medical College, Purba Bardhaman, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,12]]},"reference":[{"key":"R2-20250823","doi-asserted-by":"crossref","first-page":"622","DOI":"10.7326\/0003-4819-118-8-199304150-00009","article-title":"Measuring health-related quality of life","volume":"118","author":"Guyatt","year":"1993","journal-title":"Ann Intern Med"},{"key":"R4-20250823","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1365-2516.2005.01077.x","article-title":"An exploration of health-related quality of life in adults with haemophilia \u2013 A qualitative perspective","volume":"11","author":"Beeton","year":"2005","journal-title":"Haemophilia"},{"key":"R5-20250823","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2516.2006.01346.x","article-title":"Comparing two measures of quality of life for children with haemophilia: The CHO-KLAT and the haemo-qoL","volume":"12","author":"Bradley","year":"2006","journal-title":"Haemophilia"},{"key":"R6-20250823","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1046\/j.1365-2516.1999.00347.x","article-title":"Assessing health-related quality-of-life in individuals with haemophilia","volume":"5","author":"Miners","year":"1999","journal-title":"Haemophilia"},{"key":"R7-20250823","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1002\/ajh.10191","article-title":"Health status and health-related quality of life associated with hemophilia","volume":"71","author":"Barr","year":"2002","journal-title":"Am J Hematol"},{"key":"R8-20250823","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1046\/j.1365-2516.2002.00599.x","article-title":"Evaluation of outcome of care in patients with haemophilia","volume":"8","author":"Beeton","year":"2002","journal-title":"Haemophilia"},{"key":"R10-20250823","doi-asserted-by":"crossref","first-page":"2214","DOI":"10.1182\/blood.V104.11.2214.2214","article-title":"Development and pilot testing of a disease-specific quality of life questionnaire for adult patients with haemophilia (Haem-A-QoL)","volume":"104","author":"von Mackensen","year":"2004","journal-title":"Blood"},{"issue":"Suppl 3","key":"R11-20250823","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1365-2516.2006.01257.x","article-title":"Quality of life assessment in clinical practice in haemophilia treatment","volume":"12","author":"Gringeri","year":"2006","journal-title":"Haemophilia"},{"key":"R12-20250823","doi-asserted-by":"crossref","first-page":"A165","DOI":"10.1016\/S1098-3015(10)70524-6","article-title":"Linguistic validation of the Haemo-QoL and Haem-A-QoL for use in international studies","volume":"11","author":"Chevallet","year":"2008","journal-title":"Value Health"},{"key":"R13-20250823","doi-asserted-by":"crossref","first-page":"449","DOI":"10.3109\/08880018.2010.489933","article-title":"Hemophilia-specific quality of life index (Haemo-qoL and haem-A-qoL questionnaires) of children and adults: Result of a single center from Turkey","volume":"27","author":"Mercan","year":"2010","journal-title":"Pediatr Hematol Oncol"},{"key":"R14-20250823","doi-asserted-by":"crossref","first-page":"314","DOI":"10.5581\/1516-8484.20130108","article-title":"Health-related quality of life in hemophilia: Results of the hemophilia-specific quality of life index (Haem-a-qol) at a Brazilian blood center","volume":"35","author":"Ferreira","year":"2013","journal-title":"Rev Bras Hematol Hemoter"}],"container-title":["Journal of Education and Health Promotion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jehp.jehp_249_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:27:32Z","timestamp":1787837252000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jehp.jehp_249_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/jehp.jehp_249_19","relation":{},"ISSN":["2277-9531","2319-6440"],"issn-type":[{"value":"2277-9531","type":"print"},{"value":"2319-6440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12]]},"assertion":[{"value":"2019-05-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-23","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}