{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:32:57Z","timestamp":1786739577037,"version":"build-2736575974"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>Over the past few years, a growing body of evidence has allowed us to ascertain that the initiation of periodontitis stems from the existence of oral microbial biofilm and that this requires definitive treatment. Owing to its exceptional usability, affordability, and antibacterial activity, the \u201cdiode laser\u201d (DL) has increasingly become a popular and important tool in a dentist's armamentarium. However, there is a scarcity of scientific evidence on the utility and advantages of using \u201cdiode laser\u201d in periodontal flap surgery. The study aimed to determine the efficacy of 940 nm diode laser exposure in combination with conventional periodontal flap surgery for the treatment of chronic periodontitis to evaluate postoperative discomfort and clinical parameters.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>MATERIALS AND METHODS:<\/jats:title>\n                    <jats:p>\n                      A total of 10 subjects (7 males and 3 females) with generalized chronic periodontitis were recruited and completed the study without any dropouts. For this split-mouth study, 40 sample sites with pocket probing depth (PPD) 5\u20137 mm post periodontal Phase I therapy were selected. The quadrants were randomly allocated to Groups A, B, C, and D using the fish bowl lottery method. Kirkland flap surgery with laser and modified Widman flap (MWF) with laser were performed in Group A and C, respectively, while Kirkland flap surgery and MWF surgery were performed in Group B and Group D. Clinical parameters including visual analog scale (VAS) score and gingival inflammation were determined at 3\n                      <jats:sup>rd<\/jats:sup>\n                      and 7\n                      <jats:sup>th<\/jats:sup>\n                      day postoperatively while PPD, clinical attachment level (CAL), and sulcus bleeding index (SBI) were recorded at baseline and 6 months following treatment. Wilcoxon signed-rank test and Kruskal\u2013Wallis test were used for intra-group and inter-group comparison of parameters, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>\n                      Statistically significant difference was attained with postoperative discomfort in laser-assisted groups on 1\n                      <jats:sup>st<\/jats:sup>\n                      and 3\n                      <jats:sup>rd<\/jats:sup>\n                      day postoperatively (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). There was no significant difference in the proportion of subjects with gingival inflammation. A statistically significant reduction in mean PPD at 6 months postoperatively was seen among all study groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05) but the inter-group difference was not statistically significant. SBI score reduced significantly from baseline to 6 months follow-up among all four groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). However, we did not find the inter-group difference to be statistically non-significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSION:<\/jats:title>\n                    <jats:p>Diode laser as an adjunct to the surgical procedure can demonstrate appreciable benefits by increasing the CAL and minimizing the postoperative pain and the probing pocket, but such additional effects were not observed with gingival inflammation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jehp.jehp_568_22","type":"journal-article","created":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T04:28:18Z","timestamp":1674880098000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["Comparative evaluation of postoperative pain and tissue response in patients undergoing conventional flap surgeries with or without 940 nm diode laser exposure - A randomized clinical study"],"prefix":"10.4103","volume":"11","author":[{"given":"Sonali","family":"Roy","sequence":"first","affiliation":[{"name":"Department of Periodontology and Oral Implantology, Kalinga Institute of Dental Sciences- KIIT Deemed to be University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhirendra K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Implantology, Kalinga Institute of Dental Sciences- KIIT Deemed to be University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balaji","family":"Manohar","sequence":"additional","affiliation":[{"name":"Department of Periodontology and Oral Implantology, Kalinga Institute of Dental Sciences- KIIT Deemed to be University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,12,28]]},"reference":[{"key":"R1-20260529","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1111\/j.1600-0757.2006.00174.x","article-title":"The breadth of bacterial diversity in the human periodontal pocket and other oral sites","volume":"42","author":"Paster","year":"2006","journal-title":"Periodontol 2000"},{"key":"R2-20260529","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1111\/j.1600-0757.2010.00350.x","article-title":"Microbial shift and periodontitis","volume":"55","author":"Berezow","year":"2011","journal-title":"Periodontol 2000"},{"key":"R3-20260529","doi-asserted-by":"crossref","first-page":"152","DOI":"10.4103\/jehp.jehp_66_18","article-title":"Periodontal therapy as an adjunctive modality for HbA1c reduction in type-2 diabetic patients","volume":"7","author":"Sundar","year":"2018","journal-title":"J Educ Health Promot"},{"key":"R4-20260529","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s00784-019-03188-1","article-title":"The impact of nonsurgical periodontal treatment on oral health-related quality of life: A systematic review and meta-analysis","volume":"24","author":"Botelho","year":"2020","journal-title":"Clin Oral Invest"},{"key":"R5-20260529","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1080\/14764172.2018.1525744","article-title":"Lasers in non-surgical periodontal treatment- A review","volume":"21","author":"Sumra","year":"2018","journal-title":"J Cosmet Laser Ther"},{"key":"R6-20260529","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1902\/jop.1974.45.8.2.601","article-title":"The MWF","volume":"45","author":"Ramfjord","year":"1974","journal-title":"J Periodontol"},{"key":"R7-20260529","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.34172\/jlms.2021.42","article-title":"Low-level laser therapy: Potential and complications","volume":"12","author":"Arjmand","year":"2021","journal-title":"J Lasers Med Sci"},{"key":"R8-20260529","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1902\/annals.1996.1.1.443","article-title":"Non-surgical pocket therapy: Mechanical","volume":"1","author":"Cobb","year":"1996","journal-title":"Ann Periodontol"},{"key":"R9-20260529","doi-asserted-by":"crossref","first-page":"98","DOI":"10.3390\/jpm11020098","article-title":"Assessment of human gingival fibroblast proliferation after laser stimulation in vitro using different laser types and wavelengths (1064, 980, 635, 450, and 405 nm)\u2014Preliminary report","volume":"11","author":"Stercza\u0142a","year":"2021","journal-title":"J Pers Med"},{"key":"R10-20260529","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.3390\/antibiotics10101178","article-title":"Clinical efficacy of repeated applications of local drug delivery and adjunctive agents in nonsurgical periodontal therapy: A systematic review","volume":"10","author":"Tan","year":"2021","journal-title":"Antibiotics (Basel)"},{"key":"R11-20260529","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1902\/jop.2015.150152","article-title":"Adjunctive non-surgical therapy of inflamed periodontal pockets during maintenance therapy using diode laser: A Randomized clinical trial","volume":"86","author":"Nguyen","year":"2015","journal-title":"J Periodontol"},{"key":"R12-20260529","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/0002-9610(71)90482-X","article-title":"Effect of laser rays on wound healing","volume":"122","author":"Mester","year":"1971","journal-title":"Am J Surg"},{"key":"R13-20260529","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1080\/09553002.2019.1524944","article-title":"Assessing the impact of low level laser therapy (LLLT) on biological systems: A review","volume":"95","author":"Mussttaf","year":"2019","journal-title":"Int J Radiat Biol"},{"key":"R14-20260529","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1111\/idh.12169","article-title":"Effect of gallium aluminium arsenide diode laser therapy on Porphyromonas gingivalis in chronic periodontitis: A randomized controlled trial","volume":"14","author":"Alzoman","year":"2016","journal-title":"Int J Dent Hyg"},{"key":"R15-20260529","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/j.1600-051X.1984.tb01314.x","article-title":"Reproducibility of pocket depth and attachment level measurements when using a flexible splint","volume":"11","author":"Isidor","year":"2005","journal-title":"J Clin Periodontol"},{"key":"R16-20260529","first-page":"1462","article-title":"The suppurative periodontal pus pocket; its treatment by the modified flap operation","volume":"18","author":"Kirkland","year":"1931","journal-title":"J Am Dent Assoc"},{"key":"R17-20260529","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/prd.12080","article-title":"Periodontal and peri-implant wound healing following laser therapy","volume":"68","author":"Aoki","year":"2015","journal-title":"Periodontal 2000"},{"key":"R18-20260529","doi-asserted-by":"crossref","first-page":"145","DOI":"10.4103\/jisp.jisp_101_19","article-title":"Clinical and microbiological evaluation of the synergistic effects of diode laser with nonsurgical periodontal therapy: A randomized clinical trial","volume":"24","author":"Manjunath","year":"2020","journal-title":"J Indian Soc Periodontol"},{"key":"R19-20260529","doi-asserted-by":"crossref","first-page":"445","DOI":"10.4103\/jispcd.JISPCD_216_20","article-title":"Influence of an 810-nm diode laser on the temperature changes of the external root surface: An in vitro study","volume":"10","author":"Shehab","year":"2020","journal-title":"J Int Soc Prev Community Dent"},{"key":"R20-20260529","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1089\/pho.2010.2928","article-title":"Inhibitory effects of laser irradiation on peripheral mammalian nerves and relevance to analgesic effects: A systematic review","volume":"29","author":"Chow","year":"2011","journal-title":"Photomed Laser Surg"},{"key":"R21-20260529","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/jiadsr.jiadsr_9_17","article-title":"The effect of biostimulation with 980- nm diode laser on postoperative pain and tissue response after surgical periodontal therapy: A pilot study","volume":"3","author":"Ravi","year":"2016","journal-title":"J Indian Acad Dent Spec Res"},{"key":"R22-20260529","doi-asserted-by":"crossref","first-page":"213","DOI":"10.4103\/jisp.jisp_252_20","article-title":"Comparative evaluation of the efficacy of diode laser as an adjunct to MWF surgery for the treatment of chronic periodontitis: A randomized split-mouth clinical trial","volume":"25","author":"Khan","year":"2021","journal-title":"J Indian Soc Periodontal"},{"key":"R23-20260529","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1902\/jop.2012.110660","article-title":"The effect of an 810-nm diode laser on post-operative pain and tissue response after MWF surgery: A pilot study in humans","volume":"84","author":"Sanz Moliner","year":"2013","journal-title":"J Periodontal"},{"key":"R24-20260529","first-page":"91","article-title":"Effect of 810 nm diode laser on post-operative pain adjunct to periodontal flap surgery","volume":"11","author":"Nagaraj","year":"2020","journal-title":"IJPHRD"},{"key":"R25-20260529","doi-asserted-by":"crossref","first-page":"80","DOI":"10.29328\/journal.johcs.1001015","article-title":"Low Level Light Therapy (LLLT): Penetration and Photobiomodulation","volume":"2","author":"Young","year":"2017","journal-title":"J Oral Health Craniofac Sci"},{"key":"R27-20260529","first-page":"4957","article-title":"A comparative evaluation of laser assisted & conventional open flap surgical debridement procedure in patients with chronic periodontitis \u2013 A clinical and microbiological study- A pilot project","volume":"11","author":"Shetty","year":"2020","journal-title":"Int J Pharm Sci Res"},{"key":"R28-20260529","doi-asserted-by":"crossref","first-page":"384","DOI":"10.4103\/0970-9290.167626","article-title":"The clinical efficacy of laser assisted MWF: A randomized split mouth clinical trial","volume":"26","author":"Aena","year":"2015","journal-title":"Indian J Dent Res"},{"key":"R29-20260529","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/0972-124X.145808","article-title":"Evaluation of the use of a 940 nm diode laser as an adjunct in flap surgery for treatment of chronic periodontitis","volume":"19","author":"Lobo","year":"2015","journal-title":"J Indian Soc Periodontol"},{"key":"R30-20260529","first-page":"1","article-title":"Diode Laser as an adjunct to kirkland flap surgery\u2014A randomized split-mouth clinical and microbiological study","volume":"1","author":"Karthikeyan","year":"2019","journal-title":"Photomed Laser Surg"},{"key":"R31-20260529","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15761\/OHC.1000189","article-title":"Laser hazards and safety in dental practice: A review","volume":"5","author":"Boddun","year":"2020","journal-title":"Oral Health Care"}],"container-title":["Journal of Education and Health Promotion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jehp.jehp_568_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:30:11Z","timestamp":1786735811000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jehp.jehp_568_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jehp.jehp_568_22","relation":{},"ISSN":["2277-9531","2319-6440"],"issn-type":[{"value":"2277-9531","type":"print"},{"value":"2319-6440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1]]},"assertion":[{"value":"2022-04-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-07","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}