{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T01:38:37Z","timestamp":1790386717537,"version":"4.1.0"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n \n The lengthy and multi-stage nature of assisted reproductive technology (ART) can impose financial and social burdens on couples while also affecting their psychological well-being. Mindfulness-based stress reduction techniques help individuals cope effectively and cultivate inner calm. Additionally, lifestyle choices can impact fertility outcomes. In this study, we investigated the effects of mindfulness and health-promoting lifestyles on\n in vitro<\/jats:italic>\n fertilization outcomes in infertile couples.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n We conducted a randomized controlled clinical trial involving 300 infertile couples who were candidates for ART. The block randomization method randomly assigned participants to the intervention or control groups. The intervention group received an educational program of eight weeks of face-to-face interactive sessions supplemented by social media support. The control group received standard care. We compared the number of clinical pregnancies, health-promoting lifestyle scores, and anxiety levels between the two groups using Chi-square tests and independent\n t<\/jats:italic>\n -tests.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The clinical pregnancy rate in the intervention group (39.3%) was significantly higher than that in the control group (22%) (\n P<\/jats:italic>\n < 0.001). After the intervention, the mean health-promoting lifestyle scores were significantly higher in the intervention group compared to the control group (\n P<\/jats:italic>\n < 0.001). Additionally, anxiety scores were significantly lower in the intervention group (\n P<\/jats:italic>\n < 0.001).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Simultaneously improving lifestyle choices, cultivating awareness of body and soul, and maintaining a non-prejudiced attitude toward the environment can lead to better outcomes in achieving the desire for a child.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jehp.jehp_990_24","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T17:00:07Z","timestamp":1761930007000},"update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["The effects of lifestyle improvements and mindfulness-based stress reduction on pregnancy rate and anxiety in infertile women undergoing IVF: A randomized clinical trial"],"prefix":"10.4103","volume":"14","author":[{"given":"Padideh","family":"Malekpour","sequence":"first","affiliation":[{"name":"Student Research Committee of Shahroud University of Medical Sciences, Shahroud, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Motaghi","sequence":"additional","affiliation":[{"name":"Department of Reproductive Health, School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robab","family":"Hasanzadeh","sequence":"additional","affiliation":[{"name":"Department of Midwifery, Bonab Branch, Islamic Azad University, Bonab, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Chaman","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, School of Health, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farjamfar","family":"Maryam","sequence":"additional","affiliation":[{"name":"Clinical Research Development Unit, Imam Hossein Hospital Shahroud University of Medical Science, Shahroud, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mojgan Javedani","family":"Masroor","sequence":"additional","affiliation":[{"name":"Shahid Akbar-Abadi Clinical Research Development Unit (Sh A C R D U), School of Medicine, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,10]]},"reference":[{"key":"R1-20251130","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.fertnstert.2019.11.025","article-title":"Electronic address: asrm@asrm.org. Definitions of infertility and recurrent pregnancy loss: A committee opinion","volume":"113","year":"2020","journal-title":"Fertil Steril"},{"key":"R2-20251130","doi-asserted-by":"crossref","first-page":"6247","DOI":"10.3390\/ijerph18126247","article-title":"Mediating effects of emotional self-disclosure on the relationship between depression and quality of life for women undergoing in-vitro fertilization","volume":"18","author":"Kim","year":"2021","journal-title":"Int J Environ Res Public Health"},{"key":"R3-20251130","doi-asserted-by":"crossref","first-page":"21","DOI":"10.4103\/jehp.jehp_412_19","article-title":"Investigating related factors to psychological symptoms of infertile couples undergoing assisted reproductive treatment","volume":"9","author":"Abdishahshahani","year":"2020","journal-title":"J Educ Health Promot"},{"key":"R4-20251130","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/papt.12480","article-title":"Mindfulness for psychosis: Current evidence, unanswered questions and future directions","volume":"97","author":"Ellett","year":"2024","journal-title":"Psychol Psychother"},{"key":"R5-20251130","doi-asserted-by":"crossref","first-page":"177","DOI":"10.4103\/jehp.jehp_616_20","article-title":"The effectiveness of mindfulness training on coping with stress, exam anxiety, and happiness to promote health","volume":"10","author":"Zandi","year":"2021","journal-title":"J Educ Health Promot"},{"key":"R6-20251130","doi-asserted-by":"crossref","first-page":"E109","DOI":"10.1017\/sjp.2014.102","article-title":"Effect of a mindfulness program on stress, anxiety and depression in university students","volume":"17","author":"Gallego","year":"2015","journal-title":"Span J Psychol"},{"key":"R7-20251130","first-page":"1","article-title":"Influence of Hindu spiritual teachers on mindfulness-based stress reduction (MBSR) of Jon Kabat-Zinn: Focusing on the teachings of Sri Nisargadatta Maharaj and Sri Ramana Maharshi","volume":"12","author":"Wagh-Gumaste","year":"2022","journal-title":"Int J South Asian Stud"},{"key":"R8-20251130","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jpsychores.2015.03.009","article-title":"Mindfulness-based stress reduction for healthy individuals: A meta-analysis","volume":"78","author":"Khoury","year":"2015","journal-title":"J Psychosom Res"},{"key":"R9-20251130","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1007\/s12671-024-02366-x","article-title":"Mindfulness-based stress reduction health insurance coverage: If, how, and when? an integrated knowledge translation (iKT) delphi key informant analysis","volume":"15","author":"Frank","year":"2024","journal-title":"Mindfulness"},{"key":"R11-20251130","first-page":"27","article-title":"The effectiveness of mindfulness-based cognitive therapy (MBCT) on depression, anxiety and somatic symptoms in asthma patients","volume":"24","author":"Kahrizi","year":"2017","journal-title":"Razi J Med Sci"},{"key":"R12-20251130","doi-asserted-by":"crossref","first-page":"22799036231196693","DOI":"10.1177\/22799036231196693","article-title":"Mindfulness improves the mental health of infertile women: A systematic review","volume":"12","author":"Kundarti","year":"2023","journal-title":"J Public Health Res"},{"key":"R13-20251130","first-page":"142","article-title":"A study on health promoting lifestyle of university students","volume":"7","author":"Dhiman","year":"2017","journal-title":"Int J Res Eng Appl Sci"},{"key":"R15-20251130","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1186\/s12889-023-15760-2","article-title":"Health-promoting lifestyle and its predictors among health-related and non-health-related university students in Taiwan: A cross-sectional quantitative study","volume":"23","author":"Chao","year":"2023","journal-title":"BMC Public Health"},{"key":"R16-20251130","first-page":"102","article-title":"Reliability and validity of Persian version of the health-promoting lifestyle profile","volume":"20","author":"Mohammadi Zeidi","year":"2011","journal-title":"J Maz Univ Med Sci"},{"key":"R18-20251130","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.ejogrb.2016.10.050","article-title":"The effect of health-promoting lifestyle education on the treatment of unexplained female infertility","volume":"207","author":"Kaya","year":"2016","journal-title":"Eu J Obstet Gynecol Reprod Biol"},{"key":"R19-20251130","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1186\/s12978-023-01652-6","article-title":"Effectiveness of a mixed lifestyle program in couples undergoing assisted reproductive technology: A study protocol","volume":"20","author":"Malekpour","year":"2023","journal-title":"Reprod Health"},{"key":"R20-20251130","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/s12889-023-17628-x","article-title":"Treatment suspension due to the coronavirus pandemic and mental health of infertile patients: A systematic review and meta-analysis of observational studies","volume":"24","author":"Iranifard","year":"2024","journal-title":"BMC Public Health"},{"key":"R21-20251130","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1016\/j.fertnstert.2024.01.013","article-title":"Depression, anxiety, quality of life, and infertility: A global lens on the last decade of research","volume":"121","author":"Braverman","year":"2024","journal-title":"Fertil Steril"},{"key":"R23-20251130","first-page":"136","article-title":"Psychometric properties of the persian version of beck anxiety inventory (BAI)","volume":"66","author":"Kaviani","year":"2008","journal-title":"Tehran Univ Med J"},{"key":"R24-20251130","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00006199-198703000-00002","article-title":"The health-promoting lifestyle profile: Development and psychometric characteristics","volume":"36","author":"Walker","year":"1987","journal-title":"Nurs Res"},{"key":"R25-20251130","doi-asserted-by":"crossref","first-page":"e0229379","DOI":"10.1371\/journal.pone.0229379","article-title":"An internet-based mind\/body intervention to mitigate distress in women experiencing infertility: A randomized pilot trial","volume":"15","author":"Clifton","year":"2020","journal-title":"PLoS One"},{"key":"R26-20251130","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.rbmo.2017.06.014","article-title":"Healthy preconception nutrition and lifestyle using personalized mobile health coaching is associated with enhanced pregnancy chance","volume":"35","author":"van Dijk","year":"2017","journal-title":"Reprod Miomed Online"},{"key":"R27-20251130","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.mefs.2018.06.001","article-title":"Effect of mindfulness-based cognitive infertility stress therapy on psychological well-being of women with infertility","volume":"23","author":"RahmaniFard","year":"2018","journal-title":"Middle East Fertil Soc J"},{"key":"R28-20251130","doi-asserted-by":"crossref","first-page":"137","DOI":"10.32598\/irj.18.2.862.1","article-title":"The effects of mindfulness-based stress reduction group therapy on anxiety, depression, stress, and the intolerance of uncertainty in infertile women","volume":"18","author":"Mousavi","year":"2020","journal-title":"Iran Rehabil J"},{"key":"R29-20251130","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/s00737-023-01307-2","article-title":"Effects of mindfulness-based intervention for women with infertility: A systematic review and meta-analysis","volume":"26","author":"Wang","year":"2023","journal-title":"Arch Womens Ment Health"},{"key":"R30-20251130","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.21608\/ejhc.2023.293041","article-title":"Effect of maternity-led pro-fertility lifestyle intervention on health-promoting behaviors of women undergoing infertility treatment","volume":"14","author":"Masoud","year":"2023","journal-title":"Egyp J Health Care"},{"key":"R31-20251130","first-page":"33","article-title":"The effects of mindfulness-based stress reduction on psychological symptoms, quality of life, and marital satisfaction in infertile women undergoing IVF: A randomized clinical trial","volume":"13","author":"Tavousi","year":"2024","journal-title":"Nurs Midwifery Stud"},{"key":"R32-20251130","first-page":"deae119","article-title":"The clinical effectiveness of the Mind\/Body Program for Infertility on well-being and assisted reproduction outcomes: A randomized controlled trial in search for active ingredients","volume":"39","author":"Judit","year":"2024","journal-title":"Human Reprod"},{"key":"R33-20251130","first-page":"57","article-title":"Efficacy of dry cupping versus counselling with mindfulness-based cognitive therapy approach on fertility quality of life and conception success in infertile women due to polycystic ovary syndrome: A pilot randomised clinical trial","volume":"12","author":"Baghbani","year":"2024","journal-title":"Int J Community Based Nurs Midwifery"},{"key":"R34-20251130","doi-asserted-by":"crossref","first-page":"hoad036","DOI":"10.1093\/hropen\/hoad036","article-title":"A blended preconception lifestyle programme for couples undergoing IVF: Lessons learned from a multicentre randomized controlled trial","volume":"2023","author":"Boedt","year":"2023","journal-title":"Human Reprod Open"},{"key":"R35-20251130","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.anr.2014.02.002","article-title":"Effect of a mind-body therapeutic program for infertile women repeating in vitro fertilization treatment on uncertainty, anxiety, and implantation rate","volume":"8","author":"Kim","year":"2014","journal-title":"Asian Nurs Res"}],"container-title":["Journal of Education and Health Promotion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jehp.jehp_990_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:37:45Z","timestamp":1787067465000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jehp.jehp_990_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jehp.jehp_990_24","relation":{},"ISSN":["2277-9531","2319-6440"],"issn-type":[{"value":"2277-9531","type":"print"},{"value":"2319-6440","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"2024-05-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-27","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}