{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:43:54Z","timestamp":1790397834120,"version":"4.1.0"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Perforation peritonitis is a life-threatening emergency associated with high morbidity and mortality. Early risk stratification is vital, particularly in resource-limited settings. The Mannheim peritonitis index (MPI) is a widely used prognostic tool, but its performance in Vietnamese patients remains underexplored. The objective of this study was to evaluate the prognostic accuracy of MPI in predicting inhospital mortality among patients undergoing surgery for secondary peritonitis due to hollow viscus perforation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective observational study included 176 patients treated at a tertiary care center in southern Vietnam from April 2023 to May 2024. Clinical data were collected to calculate MPI scores. Mortality outcomes were analyzed using the receiver-operating characteristic curve and multivariate logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean patient age was 64.9 \u00b1 15.7 years; 70.5% were male. Generalized peritonitis occurred in 96%, and feculent contamination in 5.1%. The most frequent perforation sites were the stomach (43.8%) and duodenum (21%). Overall mortality was 21%. MPI demonstrated excellent predictive performance (area under the curve = 0.944; 95% confidence interval: 0.905\u20130.988;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). An MPI score \u226525 yielded 91.9% sensitivity and 79.9% specificity. Feculent peritonitis (odds ratio [OR] =26.5;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.020) and preoperative organ failure (OR = 51.4;\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001) were independent mortality predictors.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>MPI is a reliable and efficient tool for early mortality prediction in secondary peritonitis. A threshold score \u226525 effectively identifies high-risk patients and should be integrated into clinical decision-making in emergency surgical settings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jets.jets_109_25","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:00:09Z","timestamp":1770282009000},"page":"30-33","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Prognostic Value of the Mannheim Peritonitis Index in Predicting Mortality Following Emergency Surgery for Hollow Viscus Perforation"],"prefix":"10.4103","volume":"19","author":[{"given":"Hong Quan","family":"Dang","sequence":"first","affiliation":[{"name":"Department of Surgery, Faculty of Medicine, Can Tho University of Medicine and Pharmacy, Can Tho, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Van Bi","family":"Nguyen","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Can Tho Central General Hospital, Can Tho, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quoc Viet","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Can Tho Central General Hospital, Can Tho, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hoai Thuong","family":"Duong","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Can Tho Central General Hospital, Can Tho, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuong Tri","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Can Tho Central General Hospital, Can Tho, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Van Phu","family":"La","sequence":"additional","affiliation":[{"name":"Department Of General Surgery, Can Tho City General Hospital, Can Tho, Vietnam"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"R1-20260416","first-page":"e36620","article-title":"The role of the Mannheim peritonitis index for predicting outcomes in patients with perforation peritonitis in a rural hospital in India","volume":"15","author":"Ramteke","year":"2023","journal-title":"Cureus"},{"key":"R2-20260416","first-page":"296","article-title":"Effectiveness of Mannheim peritonitis index in predicting the morbidity and mortality of patients with hollow viscus perforation","volume":"16","author":"Karki","year":"2018","journal-title":"Kathmandu Univ Med J (KUMJ)"},{"key":"R3-20260416","first-page":"147","article-title":"Validation of MPI and PIA II in two different groups of patients with secondary peritonitis","volume":"48","author":"Kologlu","year":"2001","journal-title":"Hepatogastroenterology"},{"key":"R4-20260416","first-page":"169","article-title":"Mannheim peritonitis index\u2014prediction of risk of death from peritonitis: construction of a statistical and validation of an empirically based index","volume":"1","author":"Wacha","year":"1987","journal-title":"Theoretical Surgery"},{"key":"R5-20260416","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1002\/bjs.1800810217","article-title":"Prediction of outcome using the Mannheim peritonitis index in 2003 patients. Peritonitis study group","volume":"81","author":"Billing","year":"1994","journal-title":"Br J Surg"},{"key":"R6-20260416","first-page":"e59631","article-title":"Effectiveness of Mannheim\u2019s peritonitis index in patients with peritonitis secondary to hollow viscus perforation in a tertiary care hospital in Jharkhand, India","volume":"16","author":"Gaurav","year":"2024","journal-title":"Cureus"},{"key":"R7-20260416","first-page":"e20222991","article-title":"Mannheim\u2019s peritonitis index in the prediction of postoperative outcome of peritonitis","volume":"49","author":"Gueiros","year":"2022","journal-title":"Rev Col Bras Cir"},{"key":"R8-20260416","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1007\/s13304-020-00831-5","article-title":"Clinical evaluation of the Mannheim prognostic index in post-operative peritonitis: A prospective cohort study","volume":"72","author":"Neri","year":"2020","journal-title":"Updates Surg"},{"key":"R9-20260416","doi-asserted-by":"crossref","first-page":"243","DOI":"10.11138\/gchir\/2016.37.6.243","article-title":"Mannheim peritonitis index (MPI) and elderly population: Prognostic evaluation in acute secondary peritonitis","volume":"37","author":"Salamone","year":"2016","journal-title":"G Chir"},{"key":"R10-20260416","doi-asserted-by":"crossref","first-page":"179","DOI":"10.33314\/jnhrc.v19i1.3258","article-title":"Evaluation of Mannheim\u2019s peritonitis index in prediction of mortality in patients with non-traumatic hollow viscus perforation peritonitis","volume":"19","author":"Shakya","year":"2021","journal-title":"J Nepal Health Res Counc"},{"key":"R11-20260416","first-page":"43","article-title":"Mortality rate of secondary peritonitis and the prognostic value of the Mannheim score","volume":"18","author":"Hai","year":"2014","journal-title":"Ho Chi Minh City Med J"},{"key":"R12-20260416","first-page":"693","article-title":"Predictive power of Mannheim peritonitis index","volume":"15","author":"Qureshi","year":"2005","journal-title":"J Coll Physicians Surg Pak"},{"key":"R13-20260416","first-page":"197","article-title":"Evaluation of Mannheim peritonitis index and multiple organ failure score in patients with peritonitis","volume":"24","author":"Notash","year":"2005","journal-title":"Indian J Gastroenterol"}],"container-title":["Journal of Emergencies, Trauma, and Shock"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jets.jets_109_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:36:11Z","timestamp":1787844971000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jets.jets_109_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jets.jets_109_25","relation":{},"ISSN":["0974-2700","0974-519X"],"issn-type":[{"value":"0974-2700","type":"print"},{"value":"0974-519X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-07-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}