{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:42:54Z","timestamp":1786725774257,"version":"build-2736575974"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,12]]},"abstract":"\n Introduction:<\/jats:title>\n This study attempts to generate preliminary data regarding post-COVID pulmonary fungal infections, namely, COVID-19-associated pulmonary aspergillosis (CAPA), COVID-19-associated pulmonary mucormycosis (CAPM), and mixed infections from the Himalayas and compares the micro-radio-clinical profile and outcomes of the affected patients.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n A retrospective data analysis was conducted, where clinical profiles, microbiological and radiological reports, and outcomes of\n n<\/jats:italic>\n = 16 patients of post-COVID pulmonary infections were compared.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Of\n n<\/jats:italic>\n = 16 patients,\n n<\/jats:italic>\n = 7 had CAPA (\n n<\/jats:italic>\n = 5\n Aspergillus fumigatu<\/jats:italic>\n s,\n n<\/jats:italic>\n = 1\n Aspergillus flavus, and n =<\/jats:italic>\n 1\n Aspergillus niger<\/jats:italic>\n ),\n n<\/jats:italic>\n = 5 CAPM (Rhizopus arrhizus)\n ,<\/jats:italic>\n and\n n<\/jats:italic>\n = 4 with mixed infections (\n n =<\/jats:italic>\n 3 infected with\n Aspergillus fumigatus<\/jats:italic>\n and\n Rhizopus<\/jats:italic>\n spp. and\n n<\/jats:italic>\n = 1 with\n Aspergillus flavus<\/jats:italic>\n and\n Rhizopus arrhizus<\/jats:italic>\n ). Thick-walled cavitary lesions, air\u2013fluid levels, and multiple centrilobular nodules were some of the common radiological findings reported among these patients.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n The immuno-compromised state following COVID-19 infection and treatment might be responsible for the progression of regular exposure to the dense Himalayan vegetation into an invasive pulmonary fungal infection. Suspecting post-COVID pulmonary fungal infection is necessary for primary care physicians to ensure timely referral to higher centers. Mixed pulmonary fungal infections (coinfection with\n Aspergillus<\/jats:italic>\n spp. and\n Rhizopus<\/jats:italic>\n spp.) are also emerging as important sequelae of COVID-19.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1073_23","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T16:07:00Z","timestamp":1702915620000},"page":"3228-3235","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Post-COVID pulmonary fungal infections: An unanticipated predicament or a ticking time bomb? Clinico-microbiological profile of cases encountered during the second wave of COVID-19 pandemic at a teaching hospital in the Himalayas with a brief literature review"],"prefix":"10.4103","volume":"12","author":[{"given":"Oshin","family":"Puri","sequence":"first","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Udayakumar S.","family":"Rekha","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, 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