{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:42Z","timestamp":1786650102066,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Envenoming and deaths resulting from snake bite are a particularly important public health problem in the tropical world, with the highest burden in rural areas of South East Asia and Africa. Snake bite is one of the most severe \u201cNeglected Tropical Diseases\u201d in the world and more importantly in this part of India. We present a case of hemotoxic snake bite where the coagulation parameters remained deranged for a longer time without any active bleeding manifestations, despite treatment with Anti-Snake Venom (ASV) as per the National Treatment Guidelines. Indian Snake Bite Management Protocol emphasizes on the Role of Whole Blood Clotting Time (WBCT) as a bedside, accessible and feasible test for assessment of coagulopathy even in rural settings. Certain scenarios where the patients present late to our hospital with Snake Bite and Venom Induced Consumption Coagulopathy (VICC), the decision regarding ASV prescription in such patients is quite tricky, and needs to be individualized.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_1126_22","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T07:25:32Z","timestamp":1671607532000},"page":"7448-7451","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Prolonged asymptomatic venom induced consumption coagulopathy: Caused by hemotoxic snake bite"],"prefix":"10.4103","volume":"11","author":[{"given":"Prabhat","family":"Rijal","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajay Pal","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parshika","family":"Panwar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monika","family":"Pathania","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Kant","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, All India Institute of Medical Sciences, Rishikesh, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"key":"R1-20260109","doi-asserted-by":"crossref","first-page":"e3220","DOI":"10.1371\/journal.pntd.0003220","article-title":"Current treatment for venom-induced consumption coagulopathy resulting from snakebite","volume":"8","author":"Maduwage","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"e1018","DOI":"10.1371\/journal.pntd.0001018","article-title":"Snakebite mortality in India:A nationally representative mortality survey","volume":"5","author":"Mohapatra","year":"2011","journal-title":"PLoS Negl Trop Dis"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"97","DOI":"10.4103\/0974-2700.43190","article-title":"Emergency treatment of a snake bite:Pearls from literature","volume":"1","author":"Ahmed","year":"2008","journal-title":"J Emerg Trauma Shock"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1111\/j.1538-7836.2005.01358.x","article-title":"Snake venoms and hemostasis","volume":"3","author":"Lu","year":"2005","journal-title":"J Thromb Haemost"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.toxicon.2005.02.012","article-title":"Structural considerations of the snake venom metalloproteinases, key members of the M12 reprolysin family of metalloproteinases","volume":"45","author":"Fox","year":"2005","journal-title":"Toxicon"},{"key":"R6-20260109","article-title":"Venomous reptiles and their toxins:evolution, pathophysiology and biodiscovery","year":"2015"},{"key":"R7-20260109","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1201\/9781420008661.ch5","article-title":"Snake venom metalloproteinases. Biological roles and participation in the pathophysiology of envenomation","author":"Escalante","year":"2009","journal-title":"Handbook of Venoms and Toxins of Reptiles"},{"key":"R8-20260109","doi-asserted-by":"crossref","DOI":"10.1016\/j.wem.2021.01.004","article-title":"Venom-Induced Consumption Coagulopathy Unresponsive to Antivenom After Echis Carinatus Sochureki Envenoming","author":"Gopalakrishnan","year":"2021","journal-title":"Wilderness &Environmental Medicine"},{"key":"R9-20260109","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.4269\/ajtmh.20-0035","article-title":"Case report:Management of pit viper envenoming without antivenom:A case series","volume":"102","author":"Bhatt","year":"2020","journal-title":"Am J Trop Med Hyg"},{"key":"R10-20260109","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1002\/ccr3.2598","article-title":"Is anti-snake venom required for all snakebites:A case report","volume":"8","author":"Dorji","year":"2020","journal-title":"Clin Case Rep"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1126_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:02:26Z","timestamp":1786647746000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1126_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1126_22","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"2022-05-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-08-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}