{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:02:38Z","timestamp":1787169758988,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,2]]},"abstract":"<jats:p>Partial Hemolysis, elevation of liver enzymes and low platelet count (HELLP) syndrome is a leading cause of maternal mortality. With the exceeding spread of COVID-19, leading to increasing number of COVID-19 infected cases there has been a emergence of an overlap of COVID-19 with HELLP Syndrome. Multiple factors are associated with the thrombocytopenia witnessed in COVID-19 somewhat similar to what is witnessed in preeclampsia and HELLP Syndrome. We Describe a case series of two ante natal cases who presented with a picture of HELLP syndrome and upon investigations turned out to be COVID-19 thus trying to establish an association between the two.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_1136_21","type":"journal-article","created":{"date-parts":[[2022,2,26]],"date-time":"2022-02-26T11:54:47Z","timestamp":1645876487000},"page":"802-806","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["HELLP Syndrome and COVID-19; association or accident: A case series"],"prefix":"10.4103","volume":"11","author":[{"given":"Sparsh","family":"Madaan","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences and Research (Deemed to be University), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhruv","family":"Talwar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences and Research (Deemed to be University), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences and Research (Deemed to be University), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpita","family":"Jaiswal","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences and Research (Deemed to be University), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neema","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences and Research (Deemed to be University), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sourya","family":"Acharya","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences and Research (Deemed to be University), Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,2,16]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1093\/cvr\/cvaa097","article-title":"Hypertension, the renin-angiotensin system, and the risk of lower respiratory tract infections and lung injury:implications for COVID-19","volume":"116","author":"Kreutz","year":"2020","journal-title":"Cardiovasc Res"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"494","DOI":"10.3348\/kjr.2020.0132","article-title":"Chest radiographic and CT findings of the 2019 novel coronavirus disease (COVID- 19):Analysis of nine patients treated in Korea","volume":"21","author":"Yoon","year":"2020","journal-title":"Korean J Radiol"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2393-9-8","article-title":"The HELLP syndrome:clinical issues and management. A Review","volume":"9","author":"Haram","year":"2009","journal-title":"BMC Pregnancy Childbirth"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"100120","DOI":"10.1016\/j.ajogmf.2020.100120","article-title":"Severe acute respiratory distress syndrome in coronavirus disease 2019 -infected pregnancy:Obstetric and intensive care considerations","volume":"2","author":"Schnettler","year":"2020","journal-title":"Am J Obstet Gynecol MFM"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1016\/S0140-6736(20)30360-3","article-title":"Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women:a retrospective review of medical records","volume":"395","author":"Chen","year":"2020","journal-title":"Lancet"},{"key":"B6-20240828","first-page":"1878","article-title":"Fatal HELLP syndrome in pregnancy:A sequelae of Long COVID?","volume":"25","author":"Mahajan","year":"2021","journal-title":"Med Sci"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1186\/s12884-021-04030-x","article-title":"Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome:A case report","volume":"21","author":"Norooznezhad","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"B8-20240828","first-page":"247","article-title":"COVID-19 and HELLP Syndrome, uncertain diagnosis:Case report","volume":"89","author":"Mart\u00ednez-Mart\u00ednez","year":"2021","journal-title":"Ginecol Obstet Mex"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12884-020-03172-8","article-title":"Complicated COVID-19 in pregnancy:A case report with severe liver and coagulation dysfunction promptly improved by delivery","volume":"20","author":"Ronnje","year":"2020","journal-title":"BMC Pregnancy Childbirth"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1055\/s-0040-1712978","article-title":"COVID-19 and HELLP:Overlapping clinical pictures in two gravid patients","volume":"10","author":"Futterman","year":"2020","journal-title":"Am J Perinatol Rep"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1136_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:11:45Z","timestamp":1787166705000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1136_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1136_21","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"2021-06-11","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}