{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:29:25Z","timestamp":1786739365760,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2021,2,1]],"date-time":"2021-02-01T00:00:00Z","timestamp":1612137600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>Bupropion is taken as an antidepressant for treatment of major depressive disorders, treatment of sexual side effects of selective serotonin reuptake inhibitors, and as a smoking cessation aid, however, it may result in adverse effects such as nausea, dry mouth, headache, insomnia, dizziness, anxiety, tremor, and constipation. We investigate the case of a 34-year-old woman with bulimia nervosa where acute dystonia was induced by bupropion in 8 months. Following this diagnosis and after normal tests and MRI results, the patient was advised to discontinue bupropion intake. In the follow-up done 2 weeks later, 3 months later, and 6 months later, no signs of acute dystonia was observed. A physician who administers dopamine blocking agents must be aware of the prevalence of and the risk factors for acute dystonia and also the way of prevention and treatment.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_1173_20","type":"journal-article","created":{"date-parts":[[2021,2,26]],"date-time":"2021-02-26T15:18:45Z","timestamp":1614352725000},"page":"1034-1036","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Bupropion-induced acute dystonia in a patient with bulimia nervosa: A case report"],"prefix":"10.4103","volume":"10","author":[{"given":"Parvane","family":"Rashidpour","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi, University of Medical Sciences, Yazd, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zahra","family":"Poursharif","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi, University of Medical Sciences, Yazd, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mina","family":"Ayatollahi","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi, University of Medical Sciences, Yazd, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elham","family":"Farzannejad","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi, University of Medical Sciences, Yazd, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,2]]},"reference":[{"key":"R1-20260527","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1177\/2045125316629071","article-title":"Bupropion: A systematic review and meta-analysis of effectiveness as an antidepressant","volume":"6","author":"Patel","year":"2016","journal-title":"Ther Adv Psychopharmacol"},{"key":"R2-20260527","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/j.1527-3458.2006.00178.x","article-title":"Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent","volume":"12","author":"Dwoskin","year":"2006","journal-title":"CNS Drug Rev"},{"key":"R3-20260527","first-page":"159","article-title":"A review of the neuropharmacology of bupropion, a dual norepinephrine and dopamine reuptake inhibitor","volume":"6","author":"Stahl","year":"2004","journal-title":"Prim Care Companion J Clin Psychiatry"},{"key":"R4-20260527","first-page":"e4277","article-title":"Does bupropion impact more than mood? 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