{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:26:16Z","timestamp":1787840776473,"version":"build-2784847793"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Whether memory difficulty is associated with bone mineral density (BMD) is still unclear. We examined the association between memory difficulty and BMD in US adults.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>This cross-sectional study identified 4383 individuals (2581 [58.9%] males). Memory difficulty data were collected during a face-to-face interview. Femoral neck, total hip, and lumbar spine BMD were measured by a Hologic QDR-4500A fan-beam dual-energy X-ray absorptiometry (DXA); BMD T-scores were calculated using the established method.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The average age and body mass index for study participants were 39.5 years (SD = 13.4 years) and 28.6 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      (SD = 6.6 kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ), respectively. In both unadjusted and adjusted models, memory difficulty was associated with decreased femoral neck and total hip BMD T-scores (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05), but not with lumbar spine BMD T-scores. These associations were identical for males and females (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      interaction by sex &gt;0.100). The negative association between memory difficulty and hip BMD appeared to be stronger in individuals &lt;50 years old than in those \u226550 years old (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      interaction &lt;0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Memory difficulty was negatively associated with hip BMD, with stronger associations observed among individuals aged &lt;50 years old.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1183_25","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T12:00:51Z","timestamp":1774008051000},"page":"592-597","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Memory difficulty and bone mineral density: The NHANES, 2013-2018"],"prefix":"10.4103","volume":"15","author":[{"given":"Yuzhong","family":"Gao","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China"},{"name":"Department of Orthopedic and Joint Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zexuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of General Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann M.","family":"Vuong","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, University of Nevada, Las Vegas, US"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuman","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, Changchun, Jilin, China"},{"name":"Department of Orthopedic and Joint Surgery, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,3,20]]},"reference":[{"key":"R1-20260325","doi-asserted-by":"crossref","first-page":"E2613","DOI":"10.1210\/clinem\/dgab180","article-title":"An updated reference for calculating bone mineral sensity T-scores","volume":"106","author":"Xue","year":"2021","journal-title":"J Clin Endocr 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