{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:00:47Z","timestamp":1787169647982,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:p>\n                    Common variable immunodeficiency is the most common primary immunodeficiency disorder. Lipopolysaccharide (LPS)-responsive beige-like anchor protein (LRBA) deficiency is categorized as a common variable immunodeficiency associated with autoimmune manifestations and inflammatory bowel diseases. We report a rare case, an adolescent presenting with severe diabetic ketoacidosis (DKA) and acute pancreatitis with multiorgan dysfunction with common variable immunodeficiency (CVID) with homozygous\n                    <jats:italic toggle=\"yes\">LRBA<\/jats:italic>\n                    mutation.\n                  <\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_1220_21","type":"journal-article","created":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T01:12:59Z","timestamp":1648516379000},"page":"1552-1554","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Severe diabetic ketoacidosis and autoimmune pancreatitis with SIRS in an adolescent with LRBA deficiency \u2013 A rare complication of a common primary immunodeficiency disease"],"prefix":"10.4103","volume":"11","author":[{"given":"Divya","family":"Ravindran","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Reasearch (SRIHER), Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajavel Sagul Ramanuja","family":"Mugunthan","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Reasearch (SRIHER), Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tarikere Krishnamurthy","family":"Shruthi","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Reasearch (SRIHER), Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dhaarani","family":"Jayaraman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Sri Ramachandra Medical College and Research Institute, Sri Ramachandra Institute of Higher Education and Reasearch (SRIHER), Porur, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,3,18]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jaip.2015.07.025","article-title":"International consensus document (ICON):Common variable immunodeficiency disorders","volume":"4","author":"Bonilla","year":"2016","journal-title":"J Allergy Clin Immunol Pract"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1007\/s10875-017-0464-9","article-title":"International union of immunological societies:2017 Primary immunodeficiency diseases committee report on inborn errors of immunity","volume":"38","author":"Picard","year":"2018","journal-title":"J Clin 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