{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:45:45Z","timestamp":1791848745949,"version":"4.3.4"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Carpal tunnel syndrome (CTS) is considered to be one of the most common peripheral nerve disorders with female preponderance which significantly reduces work efficacy and needs further research on its preventable factors, especially obesity. We studied the effects of obesity indices on Phalen\u2019s test duration and median nerve conduction study (NCS) parameters in patients presenting with CTS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We examined 229 female patients presenting with clinical features of CTS. Clinical examinations including Phalen\u2019s test, median NCSs, and body composition were evaluated. Obesity indices and electrophysiological parameters were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      There were significant associations of both body mass index (BMI) degrees and body fat percent (BF%) with clinical and NCS parameters with a linear relationship. BF% and BMI were strongly negatively correlated with Phalen\u2019s test duration (BF%; r = -0.334, BMI; r = -0.270\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001). On the other hand, BF% and BMI were positively correlated with median distal latency (BF%; r = 0.338, BMI; r = 0.372,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.001), M-latency (BF%; r = 0.264, BMI; r = 0.285,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), median motor conduction velocity (MMCV) (BF%; r = 0.119,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.072, BMI; r = 0.173,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.009), median sensory conduction velocity (MSCV) (BF%; r = -0.195,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.003, BMI; r = 0.327,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001), and sensory nerve action potential (SNAP amplitude) (BF%; r = -.239, BMI; r = -0.350,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Nerve conduction parameters are significantly affected by obesity degree defined by BMI and BF%. Therefore, combining BMI and BF% assessments gives more clinical information regarding CTS severity and management. The true predictive value of these indices needs to be elucidated further.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1253_23","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T08:03:23Z","timestamp":1713773003000},"page":"1291-1295","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Relationship of obesity indices with clinical severity and nerve conduction studies in females presenting with median nerve compression neuropathy at the wrist"],"prefix":"10.4103","volume":"13","author":[{"given":"Fawaz","family":"Salamh","sequence":"first","affiliation":[{"name":"Department of Physiology, Clinical Physiology Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Shahid","family":"Habib","sequence":"additional","affiliation":[{"name":"Department of Physiology, Clinical Physiology Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fawzia","family":"AlRouq","sequence":"additional","affiliation":[{"name":"Department of Physiology, Clinical Physiology Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas","family":"Albarrak","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine and King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia"},{"name":"Department of Internal Medicine, College of Medicine, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thamir","family":"Al-Khlaiwi","sequence":"additional","affiliation":[{"name":"Department of Physiology, Clinical Physiology Unit, College of Medicine, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeena","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Radiology and Imaging, King Saud University Medical City, King Saud University, Riyadh, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"R1-20240828","first-page":"1306","article-title":"Carpal tunnel syndrome: Diagnosis and treatment","volume":"49","author":"Kokubo","year":"2021","journal-title":"No Shinkei Geka"},{"key":"R2-20240828","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1186\/1471-2474-12-80","article-title":"Associations of cardiovascular risk factors, carotid intima-media thickness and manifest atherosclerotic vascular disease with carpal tunnel syndrome","volume":"12","author":"Shiri","year":"2011","journal-title":"BMC Musculoskelet Disord"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jhsa.2007.10.014","article-title":"Comparison of sonography and electrodiagnostic testing in the diagnosis of carpal tunnel syndrome","volume":"33","author":"Kwon","year":"2008","journal-title":"J. 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