{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:24:23Z","timestamp":1787757863097,"version":"build-2784847793"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Medical abortion using mifepristone-misoprostol regimen has been considered to be a safe and effective method for pregnancy termination. Misoprostol is a frequently used well tolerated drug with mild and transient side effects. Considering the safety profile mifepristone-misoprostol regimen has also been advocated by many for home-based medical abortion. However, we report herein a rare case of hypersensitivity reaction to sublingual misoprostol administered for first trimester medical abortion, where timely diagnosis and prompt intervention prevented life-threatening airway obstruction. The possibility of such rare event should be kept in mind and included in patient counselling and information especially for those who opt for outpatient abortion care so that they can seek medical help at the earliest.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1301_21","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T07:41:10Z","timestamp":1653464470000},"page":"2226-2227","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["A rare case of misoprostol hypersensitivity"],"prefix":"10.4103","volume":"11","author":[{"given":"Rituparna","family":"Das","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subrat","family":"Panda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nalini","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Deb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-104-20240828","first-page":"QD01","article-title":"Misoprostol induced convulsion- A rare side effect of misoprostol","volume":"11","author":"Sharma","year":"2017","journal-title":"J Clin Diagn Res"},{"key":"R5-104-20240828","first-page":"5775","article-title":"A comparative study on the effectiveness, safety and acceptability of medical abortion at home between gestational age up to 49 days and from 50 to 63 days","volume":"6","author":"Sharma","year":"2017","journal-title":"Int J Curr Adv Res"},{"key":"R6-104-20240828","doi-asserted-by":"crossref","first-page":"223","DOI":"10.4236\/ijcm.2012.33044","article-title":"Hypersensitivity reaction to misoprostol\u2014 A case report","volume":"3","author":"Madaan","year":"2012","journal-title":"Int JClin Med"},{"key":"R7-104-20240828","doi-asserted-by":"crossref","first-page":"195","DOI":"10.4103\/1115-2613.278583","article-title":"Sublingual misoprostol allergy: A case report","volume":"28","author":"Chinonye","year":"2019","journal-title":"Nigerian J Med"},{"key":"R8-104-20240828","doi-asserted-by":"crossref","first-page":"636","DOI":"10.5468\/ogs.2018.61.5.636","article-title":"Anaphylactic shock to vaginal misoprostol: Arare adverse reaction to a frequently used drug","volume":"61","author":"Shin","year":"2018","journal-title":"Obstet Gynecol Sci"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1301_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:55:21Z","timestamp":1787756121000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1301_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":5,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1301_21","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}