{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T05:12:39Z","timestamp":1791695559578,"version":"4.3.4"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Introduction:<\/jats:title>\n Scrub typhus is an acute febrile illness that is seen in many parts of India. Acute kidney injury (AKI) can occur in patients with scrub typhus who are not diagnosed and treated in the early stage of the disease. Such patients can have associated electrolyte abnormalities also.<\/jats:p>\n <\/jats:sec>\n \n Objectives:<\/jats:title>\n This study was done to find out the incidence of occurrence of AKI and electrolyte abnormalities among patients with scrub typhus and correlate the latter with the severity of AKI.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This prospective, observational study included 38 patients with scrub typhus admitted to a tertiary care hospital in south India. Serum sodium and serum potassium levels of all the patients were measured at hospital admission. Also, serum creatinine levels of patients on all days of the hospital stay was measured along with other parameters like hemoglobin, leucocyte count, and platelet count.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n The incidence of AKI among patients with scrub typhus was 13.16%. However, electrolyte abnormalities though seen in the patients did not correlate with AKI.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n AKI is not an uncommon phenomenon in patients with scrub typhus. Electrolyte abnormalities in these patients did not correlate with the severity of AKI.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1407_20","type":"journal-article","created":{"date-parts":[[2021,1,26]],"date-time":"2021-01-26T09:31:56Z","timestamp":1611653516000},"page":"187-191","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Acute kidney injury and electrolyte abnormalities in patients with scrub typhus admitted to a tertiary care hospital in southern India"],"prefix":"10.4103","volume":"10","author":[{"given":"Raghav","family":"Grover","sequence":"first","affiliation":[{"name":"Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vadivelan","family":"Mehalingam","sequence":"additional","affiliation":[{"name":"Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2021,1]]},"reference":[{"key":"R1-20260813","doi-asserted-by":"crossref","first-page":"591","DOI":"10.4103\/0971-5916.171289","article-title":"Outbreak of scrub typhus in Puducherry & Tamil Nadu during cooler months","volume":"142","author":"Stephen","year":"2015","journal-title":"Indian J Med Res"},{"key":"R2-20260813","doi-asserted-by":"crossref","first-page":"883","DOI":"10.4103\/1319-2442.265464","article-title":"Scrub typhus-associated acute kidney injury: A study from a south Indian tertiary care hospital","volume":"30","author":"Jayaprakash","year":"2019","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"R3-20260813","doi-asserted-by":"crossref","first-page":"e2605","DOI":"10.1371\/journal.pntd.0002605","article-title":"Scrub typhus is an under-recognized cause of acute febrile illness with acute kidney injury in India","volume":"8","author":"Kumar","year":"2014","journal-title":"PLoS Negl Trop Dis"},{"key":"R4-20260813","first-page":"1","article-title":"KDIGO clinical practice guidelines for acute kidney injury","volume":"2","author":"Kellum","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"R5-20260813","doi-asserted-by":"crossref","first-page":"956","DOI":"10.4103\/1319-2442.239633","article-title":"Epidemiology and outcome of acute kidney injury from a tertiary care hospital in India","volume":"29","author":"Vikrant","year":"2018","journal-title":"Saudi J Kidney Dis Transpl"},{"key":"R6-20260813","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.3109\/0886022X.2013.828257","article-title":"Scrub typhus associated acute kidney injury-A study from a tertiary care hospital from western Himalayan state of India","volume":"35","author":"Vikrant","year":"2013","journal-title":"Ren Fail"},{"key":"R7-20260813","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1007\/s10157-012-0753-9","article-title":"Acute kidney injury in scrub typhus","volume":"17","author":"Attur","year":"2013","journal-title":"Clin Exp Nephrol"},{"key":"R8-20260813","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.jiac.2013.08.007","article-title":"Clinical characteristics of acute kidney injury in patients with scrub typhus--RIFLE criteria validation","volume":"20","author":"Sun","year":"2014","journal-title":"J Infect Chemother"},{"key":"R9-20260813","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1093\/ndt\/gfq477","article-title":"Acute kidney injury in tropical acute febrile illness in a tertiary care centre\u2014RIFLE criteria validation","volume":"26","author":"Basu","year":"2010","journal-title":"Nephrol Dial Transplant"},{"key":"R10-20260813","doi-asserted-by":"crossref","first-page":"246","DOI":"10.5455\/2320-6012.ijrms20140247","article-title":"A study of complications of scrub typhus in a tertiary health care institute of Uttarakhand, India","volume":"2","author":"Singh","year":"2014","journal-title":"Int J Res Med Sci"},{"key":"R11-20260813","doi-asserted-by":"crossref","first-page":"440","DOI":"10.4103\/ijn.IJN_133_17","article-title":"Renal manifestation in scrub typhus during a major outbreak in central Nepal","volume":"27","author":"Sedhain","year":"2017","journal-title":"Indian J Nephrol"},{"key":"R12-20260813","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/0972-9062.234626","article-title":"Clinical profile and risk factors associated with severe scrub typhus infection among non-ICU patients in semi-urban south India","volume":"55","author":"Premraj","year":"2018","journal-title":"J Vector Borne Dis"},{"key":"R13-20260813","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/QCO.0000000000000664","article-title":"Scrub typhus: A reemerging infection","volume":"33","author":"John","year":"2020","journal-title":"Curr Opin Infect Dis"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1407_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:18:25Z","timestamp":1787843905000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1407_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1407_20","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2020-07-10","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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