{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:30:57Z","timestamp":1786739457281,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Women with Extra hepatic portal vein obstruction (EHPVO) are mostly young and belong to Asian countries. In the Indian subcontinent, 20\u201330% variceal bleeds are caused by EHPVO. Hence pregnancy is a concern in such patients. The objective of this study is to observe the maternal and neonatal outcomes in women with EHPVO.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Method:<\/jats:title>\n                    <jats:p>Extra hepatic portal vein obstruction was studied retrospectively in 28 pregnancies in 20 women from Jan 2011 to July 2018 at a tertiary hospital in South India and the pregnancy outcomes were observed during this period. Institutional Review Board approval obtained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The mean age of the women was 24.3 years and the mean age of diagnosis was 18.5 years. Splenomegaly, thrombocytopenia and anaemia were seen in 22 (78.5%), 17 (60.7%) and 8 (28.5%) of pregnancies, respectively. Rate of abortions and preterm deliveries were 2 (7.1%,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      =28) and 10 (35.7%,\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      =28). There was one stillbirth (3.6%) in the study group. EHPVO was diagnosed in 25 (89.3%) women prenatally in our series. During pregnancy only one woman had variceal bleed, which was managed conservatively. Blood and blood product transfusion was required in 7(25%) of women and there was no maternal mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Pregnancies in EHPVO have good maternal and neonatal outcomes, provided they are taken care of by a multidisciplinary approach in a tertiary care centre.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1486_20","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T11:10:32Z","timestamp":1627557032000},"page":"2608-2613","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Maternal and neonatal outcomes in extra hepatic portal vein obstruction"],"prefix":"10.4103","volume":"10","author":[{"given":"Smitha 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An analysis","volume":"53","author":"Mandal","year":"2012","journal-title":"Singapore Med J"},{"key":"R15-28-20240828","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1016\/j.jhep.2010.06.004","article-title":"Revising consensus in portal hypertension: Report of the Baveno V consensus workshop on methodology of diagnosis and therapy in portal hypertension","volume":"53","author":"de Franchis","year":"2010","journal-title":"J Hepatol"},{"key":"R16-28-20240828","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1007\/s12664-018-0864-7","article-title":"Portal hypertension and hypersplenism in extrahepatic portal venous obstruction: Are they related","volume":"37","author":"Kilambi","year":"2018","journal-title":"Indian J Gastroenterol"},{"key":"R17-28-20240828","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.tjog.2013.11.012","article-title":"Extrahepatic portal-vein obstruction in pregnancy","volume":"54","author":"Subbaiah","year":"2015","journal-title":"Taiwan J Obstet Gynecol"},{"key":"R18-28-20240828","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1001\/jamainternmed.2017.0608","article-title":"\u03b2-blocker exposure in pregnancy and risk of fetal cardiac anomalies","volume":"177","author":"Duan","year":"2017","journal-title":"JAMA Intern Med"},{"key":"R19-28-20240828","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1111\/jch.13397","article-title":"Beta-blocker subtypes and risk of low birth weight in newborns","volume":"20","author":"Duan","year":"2018","journal-title":"J Clin Hypertens"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1486_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:06Z","timestamp":1786735746000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1486_20"}},"subtitle":["Our experience"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":18,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1486_20","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}