{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T16:21:07Z","timestamp":1787847667734,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>We report the case of an 81-year-old man with end-stage kidney disease (ESKD) who was admitted to the intensive care unit with severe gastroenteritis and hypovolemic shock. During hospitalization, he underwent hemodialysis via a subclavian catheter using the NxStage system, which was followed by a progressive daily decline in platelet count. Despite platelet transfusions and corticosteroid therapy, thrombocytopenia persisted. A comprehensive evaluation excluded secondary causes, such as infection, drug-induced thrombocytopenia, and disseminated intravascular coagulation. Upon switching to a different hemodialysis system utilizing the Diacap 18NR filter (manufacturer: B. Braun), platelet counts improved significantly over the following sessions. This case highlights the importance of recognizing dialyzer-associated thrombocytopenia and demonstrates that prompt identification and substitution of the implicated membrane can result in rapid hematologic recovery and improved patient outcomes.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_1531_25","type":"journal-article","created":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T10:00:57Z","timestamp":1770372057000},"page":"431-434","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Dialyzer-associated thrombocytopenia: Case report and brief review of the literature"],"prefix":"10.4103","volume":"15","author":[{"given":"Mohammed A.","family":"Alshehri","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusra Abdullah","family":"Alqasimi","sequence":"additional","affiliation":[{"name":"Medical student, College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Alshahrani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Husain Y.","family":"Alkhaldy","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,2,7]]},"reference":[{"key":"R1-20260206","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1001\/jama.2011.1499","article-title":"Use of electron-beam sterilized hemodialysis membranes and risk of 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hemodialysis membranes","volume":"6","author":"Nasr","year":"2013","journal-title":"Int J Nephrol Renovasc Dis"},{"key":"R9-20260206","doi-asserted-by":"crossref","first-page":"53","DOI":"10.5414\/CN108485","article-title":"NxStage dialysis system-associated thrombocytopenia:A report of two cases","volume":"85","author":"Sekkarie","year":"2016","journal-title":"Clin Nephrol"},{"key":"R10-20260206","first-page":"e38891","article-title":"From diagnosis to treatment:Navigating the clinical challenges of dialyzer-associated thrombocytopenia","volume":"15","author":"Jose","year":"2023","journal-title":"Cureus"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1531_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:27:18Z","timestamp":1787844438000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1531_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1531_25","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2025-08-17","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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