{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:46:25Z","timestamp":1787071585895,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Purpose:<\/jats:title>\n                    <jats:p>To investigate the demographic profile, risk factors, clinical manifestations, and treatment outcomes of patients with orbital mucormycosis in the post-COVID-19 context.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>Retrospective analysis was conducted on the medical records of patients diagnosed with biopsy proven orbital mucormycosis following a confirmed or suspected history of COVID-19 infection. Data regarding demographic features, personal profile, COVID-19 status, ocular manifestations, radiological findings, treatment modalities, and outcomes were collected and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among the 14 patients in the study, the duration between COVID-19 onset and mucormycosis onset was 14.1 days on average. Comorbidities, particularly diabetes mellitus and hypertension, were prevalent among both COVID-19-positive and COVID-19-negative patients. Ocular manifestations at presentation included pain (80%), lid edema (100%), restricted extraocular movements (86.67%), and proptosis (53.33%). Ethmoid sinus involvement was most common (33.34%), along with pterygopalatine and inferior orbital fissure involvement (66.67%). Sinus debridement was the primary treatment modality (93.34%), with transcutaneous retrobulbar amphotericin B (TRAM-B) used in 46.67% of cases. Among 14 patients, 80% achieved globe salvage, while 40% had improved visual acuity and motility. Significant prognostic factors included intracranial extension and ICU admission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Aggressive surgical and antifungal management, supported by a multidisciplinary approach, improves outcomes in this life-threatening condition.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_153_25","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T21:00:13Z","timestamp":1759006813000},"page":"3666-3672","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Orbital mucormycosis post-COVID-19: Demographics, clinical features, and treatment outcomes"],"prefix":"10.4103","volume":"14","author":[{"given":"Ritesh","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanisha","family":"Sehgal","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bolajoko A.","family":"Adewara","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Obafemi Awolowo University, Ile-Ife, Nigeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amita S.","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yesha","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Dayanand Medical College and Hospital, Ludhiana, Punjab, 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