{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:22Z","timestamp":1787772322204,"version":"build-2784847793"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>\n                      Gastrointestinal infections affect many people annually. The most common bacterial agents involved in these infections are enteropathogenic bacteria and in the continuation of using broad-spectrum antibiotics,\n                      <jats:italic toggle=\"yes\">Clostridium difficile<\/jats:italic>\n                      -associated diarrhea is involved, especially in hospitalized patients. The aim of the present study was to investigate the pattern of antibiotic resistance among enteropathogenic bacteria.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>In this cross-sectional study, 163 samples of patients with diarrhea in Dezful Ganjavian Hospital were examined. The samples were cultured in MacConkey, Hektoen enteric agar and GN broth, and cycloserine cefoxitin fructose agar media and incubated under standard conditions. In order to identify enteropathogenic bacteria, biochemical tests and serological confirmatory tests were used. Antibiotic resistance pattern of the isolates was investigated by Kirby\u2013Bauer disk diffusion susceptibility test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The frequency of pathogenic bacteria includes 41.1% of\n                      <jats:italic toggle=\"yes\">Shigella flexneri<\/jats:italic>\n                      , followed by 41.1% of\n                      <jats:italic toggle=\"yes\">S. sonnei<\/jats:italic>\n                      , 6.7% of Enteropathogenic\n                      <jats:italic toggle=\"yes\">E. coli<\/jats:italic>\n                      , 5.5% of\n                      <jats:italic toggle=\"yes\">Salmonella enterica<\/jats:italic>\n                      Serogroup B, and 5.5% of\n                      <jats:italic toggle=\"yes\">Shigella dysenteriae<\/jats:italic>\n                      . The results revealed a total of 46 patients with orders regarding\n                      <jats:italic toggle=\"yes\">C. difficile<\/jats:italic>\n                      culture, no\n                      <jats:italic toggle=\"yes\">C. difficile<\/jats:italic>\n                      was isolated from the samples. The studied isolates showed the highest resistance to trimethoprim-sulfamethoxazole, and ceftriaxone (88.3%), and the most effective antibiotic in the treatment of patients was ciprofloxacin with 86% sensitivity.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Susceptibility to antibiotics was different among the isolates, which shows that the early identification of the infection agent and the selection of the correct antibiotic treatment are effective in improving the gastrointestinal infection and preventing the spread of the infection.<\/jats:p>\n                  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