{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:46:02Z","timestamp":1787071562526,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To evaluate the effect of multidisciplinary management on mortality and morbidity in acute pancreatitis (AP) patients and to investigate the clinical profile and intervention requirements in patients with peripancreatic collections.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A prospective observational study was conducted in 100 AP patients admitted to a tertiary care hospital in Ludhiana. Statistical analysis was performed using SPSS21 software (SPSS Inc., Chicago, IL, USA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the 100 cases, 27% were in the 31\u201340 age group, with a male predominance (67%) and biliary etiology (44%). Radiological evidence of pancreatitis was present in 90% of cases, with peripancreatic collections in 53%. Interventions included nasojejunal feeding tube (NJFT) (66%), Percutaneous catheter drainage (PCD) insertion (34%), necrosectomy (11%), therapeutic endoscopic retrograde cholangiopancreatography (5%), and cholecystectomy (3%). Out of 100 patients, there was need for ICU admission in 58%, ventilatory support in 25%, and inotropes in 31% of the patients. Bacterial growth was detected in 90.9% of peripancreatic collection samples, with Klebsiella being the most common isolate. The mean length of stay was 19 days, with a final outcome of discharge (71%), discharge against medical advice (24%), and mortality (5%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study demonstrates a significant relationship between the severity of AP and the need for interventions, which affects the final outcome of patients, resulting in decreased morbidity and mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1599_24","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T15:04:39Z","timestamp":1758639879000},"page":"3287-3291","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Multidisciplinary interventional approach in management of acute pancreatitis-changing trends over the time"],"prefix":"10.4103","volume":"14","author":[{"given":"Abhinav","family":"Gupta","sequence":"first","affiliation":[{"name":"Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyoti","family":"Jindal","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vikas","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veenu","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Dayanand Medical College and Hospital, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhdeep 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