{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:25:12Z","timestamp":1792095912573,"version":"4.4.0"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Human immunodeficiency virus (HIV)\/acquired immunodeficiency syndrome (AIDS) remains a global health challenge, particularly in developing nations like India, with approximately 2.35 million people living with HIV. Socio-demographic factors, including education and socio-economic status, influence infection rates. This study examines the socio-demographic and clinical profiles of HIV-positive patients at an anti-retroviral therapy (ART) Centre in Maharashtra.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>This single-center, cross-sectional descriptive study assessed the socio-demographic and clinical profiles of HIV-positive patients at an ART Centre in Western Maharashtra. The sample included 400 participants aged 18 and above, selected via systematic random sampling. Data were collected through a pre-tested questionnaire covering socio-demographic details and clinical parameters, including CD4 counts and opportunistic infections. Statistical analysis was conducted using Jamovi v4.3.2, with ethical clearance obtained from the institutional ethics committee. Informed consent and data confidentiality were maintained.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 400 HIV-positive individuals participated in the study, with most aged 21\u201340 years and a slight female predominance. Half were married, and many had low educational levels, with 308 participants in the upper-lower socio-economic class. Clinical findings showed that 45.5% had a CD4 count of \u2264200 cells\/\u03bcL, indicating advanced immunosuppression. The majority were in WHO Stage II (41.8%) or Stage III (33.3%), with 48.3% experiencing opportunistic infections, predominantly candidiasis (34.3%). Adverse reactions to ART were reported by 22.3% of participants, highlighting treatment challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study highlights the socio-demographic and clinical profiles of HIV-positive patients in Maharashtra, emphasising the need for tailored public health interventions, partner testing, integrated HIV-TB services, and strengthened public\u2013private partnerships, along with robust IEC activities to enhance awareness and promote safer practices.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1698_24","type":"journal-article","created":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T04:15:05Z","timestamp":1742789705000},"page":"1104-1109","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Socio-demographic and clinical profiles of HIV (human immunodeficiency virus)-positive patients at an ART (anti-retroviral therapy) centre in western Maharashtra: A cross-sectional study"],"prefix":"10.4103","volume":"14","author":[{"given":"Richa","family":"Naik","sequence":"first","affiliation":[{"name":"Classified Specialist, Assistant Director of Health, Department of Health, 92 Base Hospital Srinagar, Srinagar, Jammu and Kashmir, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swati","family":"Ghonge","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Dr. D.Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai Mahesh","family":"Vajjala","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Dr. D.Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pimpri, Pune, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,3,25]]},"reference":[{"key":"R4-20250325","doi-asserted-by":"crossref","first-page":"343","DOI":"10.2105\/AJPH.92.3.343","article-title":"The global HIV\/AIDS pandemic, structural inequalities, and the politics of international health","volume":"92","author":"Parker","year":"2002","journal-title":"Am J Public Health"},{"key":"R5-20250325","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.18203\/2394-6040.ijcmph20181723","article-title":"Socio-demographic and clinical profile of HIV\/AIDS patients attending the ART centre of Amritsar, Punjab","volume":"5","author":"Singh","year":"2018","journal-title":"Int J Community Med Public Health"},{"key":"R6-20250325","first-page":"1568","article-title":"Socio-demographic and clinical profile of HIV\/AIDS patients visiting to ART centre at a rural 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Ahmedabad","volume":"30","author":"Sharma","year":"2009","journal-title":"Indian J Sex Transm Dis AIDS"},{"key":"R14-20250325","first-page":"339","article-title":"A study on socio-demographic profile and risk factors present in HIV infected patients attending ART centre in tertiary care hospital in Rajasthan, India","volume":"3","author":"Baig","year":"2012","journal-title":"Natl J Community Med"},{"key":"R15-20250325","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.5455\/ijmsph.2014.190620146","article-title":"Prevalence of HIV-TB co-infection, clinical profile and CD4 count of HIV patients attending ART centre of Ahmednagar, Maharashtra","volume":"3","author":"Gautam","year":"2014","journal-title":"Int J Med Sci Public Health"},{"key":"R16-20250325","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3126\/ajms.v6i5.11622","article-title":"Clinical and socio-demographic profile of attendees at ART centre in a tertiary care hospital in Mangalore, India","volume":"6","author":"Nayak","year":"2015","journal-title":"Asian J Med Sci"}],"container-title":["Journal of Family Medicine and Primary 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