{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:29:06Z","timestamp":1787758146247,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Angioedema is swelling that mostly involves the soft tissue of the eyelids, nose, throat, tongue, mouth, or genitals. Angiotensin converting enzyme inhibitors induced angioedema is a rare but potentially dangerous adverse effect. A 52-year-old female patient attended the emergency department with the history swelling over the eyes and face past 3 days and having difficulty in swallowing of the food. Her medical history revealed that the patient was recently diagnosed with hypertension and was on the combination of Telmisartan and Amlodipin (40 mg + 5 mg). The medicines were immediately stopped and the patient was managed symptomatically for angioedema. The symptoms declined after 5 days of discontinuity of medicines. The case report can be considered as rare adverse effects of the Telmisartan. Angiotensin receptor blockers induced angioedema is a rare presentation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1710_21","type":"journal-article","created":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T05:11:16Z","timestamp":1659330676000},"page":"4026-4028","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Telmisartan-induced angioedema"],"prefix":"10.4103","volume":"11","author":[{"given":"Nitesh","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhu","family":"Kiran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kapil","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shatrughan","family":"Pareek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-107-20240828","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1002\/j.1875-9114.1996.tb03651.x","article-title":"Delayed onset of angioedema with angiotensin-converting enzyme inhibitors:Case report and review of the literature","volume":"16","author":"O'Mara","year":"1996","journal-title":"Pharmacotherapy"},{"key":"R2-107-20240828","doi-asserted-by":"crossref","first-page":"230","DOI":"10.4103\/JICC.JICC_44_19","article-title":"A rare case report on telmisartan-induced angioedema and mouth ulcers","volume":"9","author":"Diwan","year":"2019","journal-title":"J Indian Coll Cardiol"},{"key":"R3-107-20240828","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1592\/phco.22.13.1176.33516","article-title":"Angioedema associated with candesartan","volume":"22","author":"Lo","year":"2002","journal-title":"Pharmacotherapy"},{"key":"R4-107-20240828","doi-asserted-by":"crossref","first-page":"106081","DOI":"10.1016\/j.intimp.2019.106081","article-title":"ACE inhibitor-mediated angioedema","volume":"78","author":"Montinaro","year":"2020","journal-title":"Int Immunopharmacol"},{"key":"R5-107-20240828","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.phrs.2015.09.007","article-title":"Cardiovascular drugs-induced oral toxicities:A murky area to be revisited and illuminated","volume":"102","author":"Balakumar","year":"2015","journal-title":"Pharmacol Res"},{"key":"R6-107-20240828","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1056\/NEJMoa0801317","article-title":"Telmisartan, ramipril, or both in patients at high risk for vascular events","volume":"358","author":"Yusuf","year":"2008","journal-title":"N Engl J Med"},{"key":"R7-107-20240828","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1097\/00005537-200110000-00011","article-title":"Angioedema associated with angiotensin IIreceptor antagonists:Challenging our knowledge of angioedema and itsetiology","volume":"111","author":"Chiu","year":"2001","journal-title":"Laryngoscope"},{"key":"R8-107-20240828","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/bcpt.13097","article-title":"Clinical experiences and case review of angiotensin II receptor blocker related angioedema in Korea","volume":"124","author":"Kim","year":"2019","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"R9-107-20240828","doi-asserted-by":"crossref","first-page":"214","DOI":"10.4103\/0976-500X.136113","article-title":"Angioedema due to fixed dose combination of telmisartan plus ramipril","volume":"5","author":"Tandon","year":"2014","journal-title":"J Pharmacol Pharmacother"},{"key":"R10-107-20240828","first-page":"1","article-title":"Incidence of adverse events with telmisartan compared with ACE inhibitors:Evidence from a pooled analysis of clinical trials","volume":"6","author":"Mancia","year":"2012","journal-title":"Patient Prefer Adherence"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1710_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:07:29Z","timestamp":1787756849000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_1710_21"}},"subtitle":["A rare clinical finding"],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_1710_21","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}