{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:40:44Z","timestamp":1787071244607,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>The need to understand the global burden of heart failure following the pandemic has arisen as a result of an increase in papers that support cardiac involvement in coronavirus disease 2019 (COVID-19). Therefore, the current study aims to provide a more thorough explanation of the function and use of cardiac biomarkers in dead and alive COVID-19 patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>All patients who were referred and admitted to Razi Hospital, Ahvaz, Iran, from March 2020 to March 2021 with a diagnosis of COVID-19 were included in this study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      During the study period, 753 patients were hospitalized with a diagnosis of COVID-19. In total, 157 cases died from the disease (case fatality rate: 20.84%). Pre-existing cerebrovascular accidents (CVAs) were more frequent in dead cases (14% vs. 6.4%). It was observed that atrial fibrillation was normal in most of the alive cases in comparison to dead patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.014). Moreover, it was seen that CRP, IL-6, and procalcitonin were increased in dead patients. Also, an association was found between ejection fraction (EF) value and death rate (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      value = 0.035). The higher frequency of positive troponin occurring in the dead group suggested a possible adverse effect on the mortality rate (22.3% vs. 16.4%).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Adults with COVID-19 commonly have cardiac manifestations, including symptoms of myocardial damage. In light of the recognized utility of troponin, ejection fraction, procalcitonin, IL-6, and CRP in COVID-19 patients with suspected myocardial damage, we should develop a safe and precise diagnostic algorithm that may contain patients\u2019 clinical histories and additional variables that may facilitate the prediction of myopericarditis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1964_23","type":"journal-article","created":{"date-parts":[[2024,9,10]],"date-time":"2024-09-10T14:14:34Z","timestamp":1725977674000},"page":"3931-3937","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of cardiac biomarkers among dead and alive COVID-19 patients in Southwest Iran"],"prefix":"10.4103","volume":"13","author":[{"given":"Seyed Mohammad Hassan","family":"Adel","sequence":"first","affiliation":[{"name":"Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"},{"name":"Department of Cardiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ebrahim Heydari","family":"Sardabi","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nehzat","family":"Akiash","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Mohammadi","sequence":"additional","affiliation":[{"name":"Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Sayadian","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanaz Saki","family":"pour","sequence":"additional","affiliation":[{"name":"Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Payam","family":"Amini","sequence":"additional","affiliation":[{"name":"Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"R1-20241104","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1080\/10408363.2020.1783198","article-title":"The COVID-19 pandemic","volume":"57","author":"Ciotti","year":"2020","journal-title":"Crit Rev Clin Lab Sci"},{"key":"R2-20241104","doi-asserted-by":"crossref","first-page":"134","DOI":"10.5694\/mja2.50698","article-title":"Clinical presentation and management of COVID-19","volume":"213","author":"Thevarajan","year":"2020","journal-title":"Med J Aust"},{"key":"R3-20241104","doi-asserted-by":"crossref","first-page":"4371","DOI":"10.1002\/ehf2.13047","article-title":"Delayed acute myocarditis and COVID-19-related multisystem inflammatory syndrome","volume":"7","author":"Nicol","year":"2020","journal-title":"ESC Heart Fail"},{"key":"R4-20241104","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.3390\/jcm9061683","article-title":"Acute coronary syndromes and Covid-19: Exploring the uncertainties","volume":"9","author":"Schiavone","year":"2020","journal-title":"J Clin Med"},{"key":"R5-20241104","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1002\/ejhf.1871","article-title":"COVID-19 and heart failure: from infection to inflammation and angiotensin II stimulation. 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