{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:52:08Z","timestamp":1791298328748,"version":"4.1.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,11]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Oral potentially malignant disorders (OPMDs), including leukoplakia, oral submucous fibrosis, and erythroplakia, are precursors to oral cancer, a major public health issue in India. The primary etiological factors for OPMDs are the use of tobacco (smoking and smokeless) and alcohol consumption, which are deeply embedded in cultural practices and contribute significantly to the rising incidence of oral cancer. The Cigarettes and Other Tobacco Products Act (COTPA) of 2003 aims to regulate tobacco usage, but implementation remains inconsistent, particularly in rural areas. This study explores the correlation between these adverse habits and OPMDs in an Indian population, aiming to develop a classification system for high-risk patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A cross-sectional study included 262 patients diagnosed with OPMDs and 100 control subjects with a history of adverse habits but no clinically visible lesions. Patient data was collected through questionnaires and medical records from the Department of Head and Neck Oncology in Kolkata, with statistical analysis performed using SYSTAT software to compare age, sex, habit history, and the prevalence of OPMDs across groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The mean age of OPMD patients was 38 years, with 100% male patients. Tobacco use (both smoking and smokeless) and alcohol consumption were significantly more prevalent in the OPMD group compared to controls. The most common clinical diagnosis was homogeneous leukoplakia, with mild dysplasia being the most frequent histopathological finding. Statistical analysis revealed a strong association between adverse habits and OPMD diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study underscores the significant role of tobacco and alcohol in the development of OPMDs and OSCC. A classification system based on demographics, habit history, and socio-economic status is proposed for effective triaging of high-risk individuals. This could enhance early detection and intervention, particularly in high-risk populations, thereby contributing to oral cancer prevention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_1993_24","type":"journal-article","created":{"date-parts":[[2025,11,28]],"date-time":"2025-11-28T11:01:12Z","timestamp":1764327672000},"page":"4623-4630","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Assessing the role of demographics and adverse habits in development of oral potentially malignant disorders-A questionnaire based cross-sectional study with introduction of a new classification system"],"prefix":"10.4103","volume":"14","author":[{"given":"Sil","family":"Shiladitya","sequence":"first","affiliation":[{"name":"Department of Oral Medicine and Radiology, North Bengal Dental College and Hospital, Thiknikata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pyne","family":"Rudra","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Dr. R. 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