{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:32:41Z","timestamp":1787070761196,"version":"build-2736575974"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Lemierre syndrome is a rare complication of an acute oropharyngeal infection. The disease is characterized by antecedent protracted pharyngitis, septic thrombophlebitis of the internal jugular vein, and secondary septic embolization to distant sites. We present a case of a previously healthy 17-year-old female with a sore throat and unilateral neck pain of 3-day duration. She tested positive for cytomegalovirus, Epstein-Barr virus, and\n                    <jats:italic toggle=\"yes\">Mycoplasma pneumoniae<\/jats:italic>\n                    . Lemierre syndrome was diagnosed by contrast-enhanced computed tomography (CT) of the neck and chest. She experienced full recovery after four weeks of combined beta-lactam antibiotic and metronidazole and no anticoagulant therapy. Lemierre syndrome remains a diagnostic challenge due to its rarity. In the post-antibiotic era, atypical causative pathogens are commonly seen. Contrast-enhanced CT of the neck serves as the gold standard for the diagnosis of Lemierre syndrome. This case highlights the importance of having a high index of suspicion for an early accurate diagnosis, appropriate treatment, and optimal outcome.\n                  <\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_2194_25","type":"journal-article","created":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T14:00:32Z","timestamp":1781791232000},"page":"2143-2146","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Lemierre syndrome making an encore in the post-antibiotic era: A case report"],"prefix":"10.4103","volume":"15","author":[{"given":"Leidi","family":"Pedraza Gonzalez","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Flushing Hospital Medical Center, Flushing, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna I.","family":"Depasupil","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Flushing Hospital Medical Center, Flushing, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronique","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Flushing Hospital Medical Center, Flushing, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Fakioglu","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Flushing Hospital Medical Center, Flushing, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Partha","family":"Chatterjee","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Flushing Hospital Medical Center, Flushing, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lily Q.","family":"Lew","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Flushing Hospital Medical Center, Flushing, New York, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,6,18]]},"reference":[{"key":"R1-20260619","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1128\/CMR.00011-07","article-title":"Human infection with Fusobacterium necrophorum (necrobacillosis), with a focus on Lemierre's syndrome","volume":"20","author":"Riordan","year":"2007","journal-title":"Clin Microbiol Rev"},{"key":"R2-20260619","first-page":"2273954","article-title":"Lemierre syndrome: A diagnosis behind the veil","author":"Au","year":"2023","journal-title":"Case Rep in Infect Dis 2023"},{"key":"R3-20260619","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1186\/1865-1380-6-40","article-title":"Lemierre's syndrome","volume":"6","author":"Eilbert","year":"2013","journal-title":"Int J Emerges Med"},{"key":"R4-20260619","doi-asserted-by":"crossref","first-page":"36","DOI":"10.55729\/2000-9666.1006","article-title":"Atypical Lemierre's syndrome. A case report and review of literature","volume":"12","author":"Qureshi","year":"2022","journal-title":"J Community Hosp Intern Med Perspect"},{"key":"R5-20260619","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2147\/IDR.S95050","article-title":"Lemierre's syndrome: Current perspectives on diagnosis and management","volume":"9","author":"Johannesen","year":"2016","journal-title":"Infect Drug Resist"},{"key":"R6-20260619","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.hrtlng.2012.02.015","article-title":"Mycoplasma pneumoniae preceding Lemierre's syndrome due to Fusobacterium nucleatum complicated by acute Epstein-Barr virus (EBV) infectious mononucleosis in an immunocompetent host","volume":"42","author":"Klein","year":"2013","journal-title":"Heart Lung"},{"key":"R7-20260619","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/joim.13114","article-title":"Patients with Lemierre syndrome have a high risk of new thromboembolic complications, clinical sequelae and death: An analysis of 712 cases","volume":"289","author":"Valerio","year":"2021","journal-title":"J Intern Med"},{"key":"R8-20260619","doi-asserted-by":"crossref","first-page":"4","DOI":"10.14740\/ijcp347","article-title":"Lemierre's syndrome: A case report of a child with partial treatment of streptococcal pharyngitis","volume":"9","author":"Pryor","year":"2020","journal-title":"Int J Clin Pediatr"},{"key":"R9-20260619","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1080\/1120009X.2018.1554992","article-title":"Antibiotic and anticoagulation therapy in Lemierre's syndrome: Case report and review","volume":"31","author":"Campo","year":"2019","journal-title":"J Chemother"},{"key":"R10-20260619","first-page":"e43685","article-title":"Lemierre's syndrome in the 21st century: A literature 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