{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:36:13Z","timestamp":1786739773355,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,8,27]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Budd-Chiari syndrome (BCS) is a rare condition affecting one in a million adults. BCS involves outflow obstruction in the hepatic venous system, which can occur anywhere between the small hepatic veins and the atrio-caval junction and cannot be due to heart, pericardial, or hepatic veno-occlusive disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation:<\/jats:title>\n                    <jats:p>We report an exceedingly rare form of BCS with less common initial clinical features in a young poor adult male patient which ignited a diagnostic uncertainty and a therapeutic challenge. The presence of the classical triad of BCS in the absence of major hepatic vein obstruction prompted the medical team to consider that the patient had a rare form of BCS. In this case, the financial condition of the patient and limited resources available restricted our ability to advance into the specific investigations. However, the patient was given symptomatic medical treatment and was followed up monthly. We also provided the patient with a statement that reaffirmed our inability to provide affordable surgical management options and called for an optimized national clinical guideline that could help the physicians deal with the challenges.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>An uncommon form of BCS in this patient provided a diagnostic challenge and therapeutic uncertainty in the low-resource settings. Primary care physicians should commence evidenced medical management based on clinical suspicion acknowledging the fact that obstruction of small hepatic veins is often not detected on an ultrasound.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_2213_20","type":"journal-article","created":{"date-parts":[[2021,8,27]],"date-time":"2021-08-27T12:53:08Z","timestamp":1630068788000},"page":"3154-3158","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Budd-Chiari syndrome in small hepatic veins"],"prefix":"10.4103","volume":"10","author":[{"given":"Emiko","family":"Sultana","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Tasdik","family":"Hasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan Rushekh","family":"Mahmood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Ansar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Podder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khan","family":"Emrul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Md. Yusuf","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-68-20240828","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jhep.2015.07.040","article-title":"European Association for the Study of the Liver, EASL Clinical Practice Guidelines: Vascular diseases of the liver","volume":"64","author":"Juan Carlos","year":"2016","journal-title":"J Hepatol"},{"key":"R3-68-20240828","first-page":"334","article-title":"Vascular liver disorders (I): Diagnosis, treatment and prognosis of Budd-Chiari syndrome","volume":"66","author":"Hoekstra","year":"2008","journal-title":"Neth J Med"},{"key":"R4-68-20240828","doi-asserted-by":"crossref","first-page":"2031","DOI":"10.1053\/j.gastro.2006.04.008","article-title":"Prevalence of the activating JAK2 tyrosine kinase mutation V617F in the Budd\u2013Chiari syndrome","volume":"130","author":"Patel","year":"2006","journal-title":"Gastroenterology"},{"key":"R6-68-20240828","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1111\/j.1478-3231.2008.01838.x","article-title":"Budd-Chiari syndrome in Sweden: Epidemiology, clinical characteristics and survival\u2013an 18-year experience","volume":"29","author":"Rajani","year":"2009","journal-title":"Liver Int"},{"key":"R7-68-20240828","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.clinre.2018.10.014","article-title":"Epidemiology of Budd-Chiari syndrome: A systematic review and meta-analysis","volume":"43","author":"Li","year":"2019","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"R8-68-20240828","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/liv.13008","article-title":"Incidence, prevalence and complications of Budd-Chiari syndrome in South Korea: A nationwide, population-based study","volume":"36","author":"Ki","year":"2016","journal-title":"Liver Int"},{"key":"R9-68-20240828","doi-asserted-by":"crossref","first-page":"536","DOI":"10.1007\/s11239-013-0959-z","article-title":"Small hepatic veins Budd-Chiari syndrome","volume":"37","author":"Riggio","year":"2014","journal-title":"J Thromb Thrombolysis"},{"key":"R10-68-20240828","doi-asserted-by":"crossref","first-page":"20180441","DOI":"10.1259\/bjr.20180441","article-title":"Budd-Chiari syndrome: Imaging review","volume":"91","author":"Bansal","year":"2018","journal-title":"Br J Radiol"},{"key":"R11-68-20240828","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1478-3231.2008.01684.x","article-title":"Budd\u2013Chiari syndrome: Illustrated review of current management","volume":"28","author":"Horton","year":"2008","journal-title":"Liver Int"},{"key":"R12-68-20240828","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1056\/NEJMra020282","article-title":"The Budd\u2013Chiari syndrome","volume":"350","author":"Menon","year":"2004","journal-title":"N Engl J Med"},{"key":"R13-68-20240828","first-page":"320","article-title":"Membranous obstruction of hepatic venous flow","volume":"22","author":"De","year":"1995","journal-title":"Tex Heart Inst J"},{"key":"R14-68-20240828","first-page":"84","article-title":"Budd-Chiari syndrome","volume":"14","author":"Sutradhar","year":"2005","journal-title":"Mymensingh Med J"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2213_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:32:42Z","timestamp":1786735962000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2213_20"}},"subtitle":["A diagnostic and therapeutic challenge in a low resource setting"],"short-title":[],"issued":{"date-parts":[[2021,8,27]]},"references-count":12,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_2213_20","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2021,8,27]]}}}