{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T00:16:53Z","timestamp":1790295413848,"version":"4.1.0"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Lactose intolerance is defined as \u201cLactose malabsorption with gastrointestinal symptoms.\u201d Also, lactose malabsorption can be defined as \u201cNot all ingested lactose was absorbed and that some has reached the large intestine.\u201d The common symptoms associated with the maldigestion of lactose are bloating, diarrhoea, nausea, and abdominal pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The current study aims to assess knowledge of people awareness of the lactose intolerance disorder and its relation to nutrition and dietary habits in Saudi Arabia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A descriptive cross-sectional approach was used targeting all accessible population in Saudi Arabia aging 18 years or more and accept to participate in the study. Data were collected from participants using an online pre-structured questionnaire. The researchers constructed the survey tool after intensive literature review and expert\u2019s consultation. The questionnaire covered the following data: participants\u2019 socio-demographic data like age, gender, and monthly income. Second section covered participants\u2019 dairy products intake with associated symptoms. Third part covered personal and family history of glucose intolerance disorder among the study participants. Awareness was assessed using multiple repose and mutually exclusive questions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 1189 participants fulfilling the inclusion criteria completed the study questionnaire. Participants ages ranged from 18 to 58 years old with mean age of 25.1 \u00b1 12.9 years. Exact of 692 (58.2%) participants were females. Exact of 104 (8.7%) of the study participants reported that they had lactose intolerance disorder which started at the age of 11 to 20 years among 41 (39.4%) and at the age of 21 to 30 years among 36 (34.6%). About 77% of the study participants know that lactose indolence disorder symptoms appear after eating dairy or its derivatives. A total of 45.8% reported that leaky gut syndrome (diarrhoea and bloating) is caused by symptoms that occur with lactose intolerance and 39.4% know lactose intolerance is an uncurable disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In conclusion, this study revealed that nearly one out of each three persons on Saudi Arabia is knowledgeable regarding lactose intolerance disorder and its related factors and relieving factors. Dairy products use in daily basis was reported among two thirds of the study population with abdominal distention and abdominal pain was the main accompanying symptoms.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_2247_21","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T10:17:00Z","timestamp":1656584220000},"page":"3118-3124","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Awareness of Lactose Intolerance Disorder in Saudi Arabia Population"],"prefix":"10.4103","volume":"11","author":[{"given":"Mohammed Attieh","family":"Alzahrani","sequence":"first","affiliation":[{"name":"Internal Medicine, College of Medicine, King Khalid University, Abha, Gastroenterology Consultant, Assir Central Hospital, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saad Khaled","family":"AlGhrab","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Yahya","family":"Althwabi","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz Abdullah","family":"Sudan","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser Saeed","family":"Jurays","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad Abdullah","family":"Alalyani","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saud Abdullah","family":"Bin Fudhayl","sequence":"additional","affiliation":[{"name":"College of Medicine, King Khalid University, Abha, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed Abdullah","family":"Alfahadi","sequence":"additional","affiliation":[{"name":"Gastroenterologist Fellow, Najran General Hospital, Najran, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahia Mohammed","family":"Asiri","sequence":"additional","affiliation":[{"name":"Gastroenterologist Fellow, King Faisal Hospital, Taif, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulaziz Saad","family":"Alshahrani","sequence":"additional","affiliation":[{"name":"Internal Medicine, College of Medicine, Najran University, Gastroenterologist Consultant, King Khalid Hospital, Najran, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"B1-20240828","first-page":"1845","article-title":"Lactose intolerance","volume":"65","author":"Swagerty","year":"2002","journal-title":"AmFam Physician"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1080\/10408690490931411","article-title":"Lactose: The milk sugar from a biotechnological perspective","volume":"44","author":"Adam","year":"2004","journal-title":"Crit Rev Food Sci Nutr"},{"key":"B3-20240828","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.nutres.2021.02.003","article-title":"Lactose intolerance: An update on its pathogenesis, diagnosis, and treatment","volume":"89","author":"Catanzaro","year":"2021","journal-title":"Nutr Res"},{"key":"B4-20240828","doi-asserted-by":"crossref","first-page":"4056","DOI":"10.1039\/C8FO00555A","article-title":"Lactose malabsorption and intolerance: A review","volume":"9","author":"Ugidos-Rodr\u00edguez","year":"2018","journal-title":"Food Funct"},{"key":"B5-20240828","doi-asserted-by":"crossref","first-page":"29","DOI":"10.4292\/wjgpt.v3.i3.29","article-title":"Lactose malabsorption and intolerance: What should be the best clinical management?","volume":"3","author":"Usai-Satta","year":"2012","journal-title":"World JGastrointest Pharmacol Ther"},{"key":"B6-20240828","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1093\/qjmed\/hcq082","article-title":"Lactose malabsorption and intolerance: A systematic review on the diagnostic value of gastrointestinal symptoms and self-reported milk intolerance","volume":"103","author":"Jellema","year":"2010","journal-title":"QJM"},{"key":"B7-20240828","doi-asserted-by":"crossref","first-page":"257","DOI":"10.5056\/jnm20094","article-title":"Lactose sensitivity and lactose malabsorption: The 2 faces of lactose intolerance","volume":"27","author":"Bouchoucha","year":"2021","journal-title":"J Neurogastroenterol Motil"},{"key":"B8-20240828","first-page":"963","article-title":"The geographic hypothesis and lactose malabsorption","volume":"23","author":"Simoons","year":"1978","journal-title":"AmJDig Dis"},{"key":"B9-20240828","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S2468-1253(17)30154-1","article-title":"Country, regional, and global estimates for lactose malabsorption in adults: A systematic review and meta-analysis","volume":"2","author":"Storhaug","year":"2017","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"B10-20240828","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1016\/S2468-1253(17)30154-1","article-title":"Country, regional, and global estimates for lactose malabsorption in adults: A systematic review and meta-analysis","volume":"2","author":"Storhaug","year":"2017","journal-title":"Lancet GastroenterolHepatol"},{"key":"B11-20240828","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/S2468-1253(17)30180-2","article-title":"What is normal and abnormal in lactose digestion?","volume":"2","author":"Misselwitz","year":"2017","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"B12-20240828","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1542\/peds.2006-1721","article-title":"Lactose intolerance in infants, children, and adolescents","volume":"118","author":"Heyman","year":"2006","journal-title":"Pediatrics"},{"key":"B13-20240828","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1093\/qjmed\/hci140","article-title":"Molecularly-defined lactose malabsorption, milk consumption and anthropometric differences in adult males","volume":"98","author":"Gugatschka","year":"2005","journal-title":"QJM"},{"key":"B14-20240828","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1097\/01.JAA.0000586344.04372.e6","article-title":"Lactose intolerance","volume":"32","author":"Louwagie","year":"2019","journal-title":"JAAPA"},{"key":"B15-20240828","doi-asserted-by":"crossref","first-page":"1994","DOI":"10.3390\/nu10121994","article-title":"Lactose intolerance, dairy avoidance, and treatment options","volume":"10","author":"Szilagyi","year":"2018","journal-title":"Nutrients"},{"key":"B16-20240828","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s40413-017-0173-0","article-title":"Lactose intolerance and gastrointestinal cow's milk allergy in infants and children\u2013common misconceptions revisited","volume":"10","author":"Heine","year":"2017","journal-title":"World Allergy Organ J"},{"key":"B17-20240828","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1159\/000493669","article-title":"Lactose intolerance: Common misunderstandings","volume":"73","author":"Di Costanzo","year":"2018","journal-title":"AnnNutr Metab"},{"key":"B18-20240828","first-page":"2687","article-title":"The association of solar ultraviolet B (UVB) with reducing risk of cancer: Multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates","volume":"26","author":"Grant","year":"2006","journal-title":"Anticancer Res"},{"key":"B19-20240828","doi-asserted-by":"crossref","first-page":"e1137400","DOI":"10.1080\/19381980.2015.1137400","article-title":"The role of geographical ecological studies in identifying diseases linked to UVB exposure and\/or vitamin D","volume":"8","author":"Grant","year":"2016","journal-title":"Dermatoendocrinol"},{"key":"B20-20240828","first-page":"11","article-title":"The normal intestinal microflora: Ecology, variability and stability","volume":"35","author":"Carman","year":"1993","journal-title":"VetHum Toxicol"},{"key":"B21-20240828","first-page":"218","article-title":"A Study on the awareness of lactose intolerance among common people in India","volume":"7","author":"Diandra","year":"2020","journal-title":"Indian J Nutr"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2247_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:01:51Z","timestamp":1787756511000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2247_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":21,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_2247_21","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"2021-11-15","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}