{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:30:41Z","timestamp":1786739441751,"version":"build-2736575974"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>It is common upon admission or during stay at a hospital or intensive care unit (ICU) for patients to present with or acquire a serum sodium abnormality. Hyponatremia, serum sodium level less than 135 mmol\/L, frequently associated with critical illnesses such as heart failure and liver cirrhosis, is an indicator of disease severity as well as a risk factor for poor prognosis. Hypernatremia, serum sodium level greater than 145 mmol\/L, results due to any ailment disabling a patient's modality of thirst or the ability to relieve it once sensed. Hypernatremia has a more frequent iatrogenic component than hyponatremia. It can develop insidiously among patients through IV fluid administration of saline; both its presentation upon admission and development during stay is associated with mortality. Hyponatremia is associated with increased mortality and its treatment with morbidity as it carries a risk of overcorrection and consequently the development of central pontine myelinolysis. This review article covers the findings, and subsequent correlation between findings sought, of six articles catering to underscore the correlation between sodium disorders and prognosis of hospitalized or critically ill patients. PubMed search engine was utilized to select articles befitting the purpose of this review. Cumulatively, this review article substantiates the need to diligently evaluate and treat serum sodium disorders in hospitalized patients to achieve better prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_2291_20","type":"journal-article","created":{"date-parts":[[2021,7,29]],"date-time":"2021-07-29T11:10:32Z","timestamp":1627557032000},"page":"2477-2481","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Prognostic importance of deranged sodium level in critically ill patients"],"prefix":"10.4103","volume":"10","author":[{"given":"Abubakar","family":"Tauseef","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Zafar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erum","family":"Syed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Thirumalareddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshat","family":"Sood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noman","family":"Lateef","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsin","family":"Mirza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20240828","doi-asserted-by":"crossref","first-page":"R162","DOI":"10.1186\/cc7162","article-title":"The epidemiology of intensive care unit-acquired hyponatraemia and hypernatraemia in medical-surgical intensive care units","volume":"12","author":"Stelfox","year":"2008","journal-title":"Crit Care"},{"key":"R2-7-20240828","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1007\/s00134-009-1692-0","article-title":"Incidence and prognosis of dysnatremias present on ICU admission","volume":"36","author":"Funk","year":"2010","journal-title":"Intensive Care Med"},{"key":"R3-7-20240828","first-page":"299","article-title":"Diagnosis and management of sodium disorders: Hyponatremia and hypernatremia","volume":"91","author":"Braun","year":"2015","journal-title":"Am Fam Physician"},{"key":"R4-7-20240828","doi-asserted-by":"crossref","first-page":"239","DOI":"10.5578\/tt.68779","article-title":"Hyponatremia prolongs hospital stay and hypernatremia better predicts mortality than hyponatremia in hospitalized patients with community-acquired pneumonia. Hastanede tedavi edilen toplumda geli\u015fen pn\u00f6monide hiponatremi hastane yat\u0131\u015f\u0131n\u0131 uzat\u0131r ve hipernatremi mortalite i\u00e7in hiponatremiden daha g\u00fc\u00e7l\u00fc bir belirte\u00e7tir","volume":"67","author":"Tokg\u00f6z Akyil","year":"2019","journal-title":"Tuberk Toraks"},{"key":"R5-7-20240828","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1186\/s12967-020-02443-4","article-title":"Intensive care unit-acquired hyponatremia in critically ill medical patients","volume":"18","author":"Sim","year":"2020","journal-title":"J Transl Med"},{"key":"R6-7-20240828","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1053\/j.ajkd.2007.08.016","article-title":"Hypernatremia in the critically ill is an independent risk factor for mortality","volume":"50","author":"Lindner","year":"2007","journal-title":"Am J Kidney Dis"},{"key":"R7-7-20240828","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1111\/imj.14777","article-title":"Admission sodium levels and hospital outcomes","volume":"51","author":"Chi","year":"2021","journal-title":"Intern Med J"},{"key":"R8-7-20240828","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1159\/000313769","article-title":"Dysnatremias in the intensive care unit","volume":"165","author":"Rosner","year":"2010","journal-title":"Contrib Nephrol"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2291_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:00Z","timestamp":1786735740000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2291_20"}},"subtitle":["A systemic literature to review"],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_2291_20","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}