{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:38:18Z","timestamp":1787841498128,"version":"build-2784847793"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Hypertension (HTN) is a prevalent and impactful health concern associated with cardiovascular morbidity and mortality. This research delves into the intricate relationship between HTN and lower urinary tract symptoms (LUTS), acknowledging the multifaceted nature of these conditions and their potential impact on individuals\u2019 quality of life.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      This cross-sectional study, conducted in Nablus, Palestine, employed convenient sampling to recruit hypertensive patients from the Ministry of Health clinics between September and December 2023. The inclusion criterion involved confirmed hypertensive patients, while the exclusion criterion included individuals with specific health conditions. The collected data included demographic, comorbidity, and lifestyle factor data. The study utilized the urogenital distress inventory 6 (UDI-6) and Incontinence Impact Questionnaire (IIQ)-7 short forms to assess urinary distress symptoms and the impact of urinary incontinence on quality of life. All the statistical analyses, including Pearson, Chi-square, Fisher\u2019s exact, Kruskal-Wallis, and Mann-Whitney tests, were performed with various tests for significance, and the significance level was set at\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Among the 351 participants meeting the inclusion criteria, females (62.1%) and married individuals (83.5%) were the predominant participants. The majority were aged 58\u201367 (42.5%), had a high school education (39.0%), and had a body mass index (BMI) of 30\u201334.9 (30.2%). Significant correlations were found between UDI-6 scores and sex, age, marital status, education level, employment status, and comorbidities. The IIQ-7 score was significantly correlated with female sex, marital status, age, comorbidities, duration of HTN, employment status, and education level. Both the UDI-6 and IIQ-7 scores revealed considerable impacts on urinary symptoms and quality of life. A significant negative correlation (r = \u22120.579) between the IIQ-7 score and UDI-6 score emphasized the interconnectedness of urinary distress symptoms and their impact on quality of life (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). These findings underscore the multifaceted nature of LUTS and their profound effects on hypertensive patients\u2019 well-being.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our study revealed a significant association between HTN and LUTS, especially among females and specific demographic groups. This emphasizes the need for comprehensive management. The observed negative impact on quality of life emphasizes the significance of adopting holistic approaches to address both conditions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_231_24","type":"journal-article","created":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T02:03:27Z","timestamp":1721959407000},"page":"3195-3202","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["An evaluation of lower urinary tract symptoms among patients with hypertension: A cross-sectional study"],"prefix":"10.4103","volume":"13","author":[{"given":"Suha","family":"Hamshari","sequence":"first","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"},{"name":"Department of Family Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Sholi","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mais Abu","family":"Jamous","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmad","family":"Taha","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Aghbar","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"},{"name":"Department of Urology, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rola Abu","family":"Alwafa","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faris","family":"Abushamma","sequence":"additional","affiliation":[{"name":"Department of Medicine, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine"},{"name":"Department of Urology, An-Najah National University Hospital, Nablus, Palestine"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,26]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1097\/MNH.0000000000000862","article-title":"Targeting inflammation in hypertension","volume":"32","author":"Deussen","year":"2023","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"R2-20240828","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1161\/HYPERTENSIONAHA.121.18192","article-title":"Hypertension pharmacological treatment in adults: A world health organization guideline executive summary","volume":"79","author":"Al-Makki","year":"2022","journal-title":"Hypertension"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1161\/CIRCULATIONAHA.115.018912","article-title":"Global disparities of hypertension prevalence and control: A systematic analysis of population-based studies from 90 countries","volume":"134","author":"Mills","year":"2016","journal-title":"Circulation"},{"key":"R4-20240828","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0090-4295(02)02243-4","article-title":"The standardisation of terminology in lower urinary tract function: Report from the standardisation sub-committee of the International Continence Society","volume":"61","author":"Abrams","year":"2003","journal-title":"Urology"},{"key":"R5-20240828","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1007\/s11136-019-02402-7","article-title":"Lower urinary tract symptoms and health-related quality of life in Hong Kong primary care: A cross-sectional study","volume":"29","author":"Choi","year":"2020","journal-title":"Qual Life Res"},{"key":"R6-20240828","first-page":"67.0","article-title":"Assessment of lower urinary tract symptoms (LUTS) in hypertensive men","volume":"61","author":"Gond\u017eetovi\u0107","year":"2018","journal-title":"Hypertension"},{"key":"R7-20240828","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1007\/s00192-015-2626-8","article-title":"Prevalence, risk factors and the bother of lower urinary tract symptoms in China: A population-based survey","volume":"26","author":"Wang","year":"2015","journal-title":"Int Urogynecol J"},{"issue":"Suppl 1","key":"R8-20240828","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1757-5672.2011.00123.x","article-title":"Association between metabolic syndrome and lower urinary tract symptoms: Evidences from epidemiological studies","volume":"4","author":"Tai","year":"2012","journal-title":"Low Urin Tract Symptoms"},{"issue":"Suppl 1","key":"R9-20240828","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/j.1757-5672.2011.00119.x","article-title":"Metabolic syndrome and lower urinary tract symptoms: Epidemiological study","volume":"4","author":"Yoon","year":"2012","journal-title":"Low Urin Tract Symptoms"},{"key":"R10-20240828","doi-asserted-by":"crossref","first-page":"329","DOI":"10.23736\/S0031-0808.21.04496-7","article-title":"Metabolic syndrome and male lower urinary tract symptoms","volume":"64","author":"Ineichen","year":"2022","journal-title":"Panminerva Med"},{"key":"R11-20240828","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1097\/MOU.0b013e3283336f3f","article-title":"Lower urinary tract symptoms, obesity and the metabolic syndrome","volume":"20","author":"Moul","year":"2010","journal-title":"Curr Opin Urol"},{"key":"R12-20240828","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/S0140-6736(05)67402-8","article-title":"The metabolic syndrome--A new worldwide definition","volume":"366","author":"Alberti","year":"2005","journal-title":"Lancet"},{"key":"R13-20240828","doi-asserted-by":"crossref","first-page":"e0130820","DOI":"10.1371\/journal.pone.0130820","article-title":"Cardiovascular risk factors and ethnicity are independent factors associated with lower urinary tract symptoms","volume":"10","author":"Lim","year":"2015","journal-title":"PLoS One"},{"key":"R14-20240828","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1046\/j.1442-2042.2003.00707.x","article-title":"Influence of hypertension on lower urinary tract symptoms in benign prostatic hyperplasia","volume":"10","author":"Sugaya","year":"2003","journal-title":"Int J Urol"},{"key":"R15-20240828","doi-asserted-by":"crossref","first-page":"1676","DOI":"10.1111\/j.1464-410X.2011.10593.x","article-title":"Commonly used antihypertensives and lower urinary tract symptoms: Results from the boston area community health (BACH) survey","volume":"109","author":"Hall","year":"2012","journal-title":"BJU Int"},{"key":"R16-20240828","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1002\/nau.20640","article-title":"Arabic validation of the short form of urogenital distress inventory (UDI-6) questionnaire","volume":"28","author":"Altaweel","year":"2009","journal-title":"Neurourol Urodyn"},{"key":"R18-20240828","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF00451721","article-title":"Health-related quality of life measures for women with urinary incontinence: The incontinence impact questionnaire and the urogenital distress inventory. continence program in women (CPW) research group","volume":"3","author":"Shumaker","year":"1994","journal-title":"Qual Life Res"},{"key":"R19-20240828","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12955-021-01721-z","article-title":"Identification of the urogenital distress inventory-6 and the incontinence impact questionnaire-7 cutoff scores in urinary incontinent women","volume":"19","author":"Skorupska","year":"2021","journal-title":"Health Qual Life Outcomes"},{"key":"R20-20240828","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.urology.2003.09.070","article-title":"Comparative analysis of lower urinary tract symptoms and bother in both sexes","volume":"63","author":"Terai","year":"2004","journal-title":"Urology"},{"key":"R21-20240828","doi-asserted-by":"crossref","first-page":"6859","DOI":"10.1038\/s41598-022-10904-7","article-title":"Association between life-style, metabolic syndrome and lower urinary tract symptoms and its impact on quality of life in men \u2265 40 years","volume":"12","author":"Jeong","year":"2022","journal-title":"Sci Rep"},{"key":"R22-20240828","doi-asserted-by":"crossref","first-page":"120","DOI":"10.5213\/inj.2015.19.2.120","article-title":"The impact of lower urinary tract symptoms on quality of life, work productivity, depressive symptoms, and sexuality in korean men aged 40 years and older: A population-based survey","volume":"19","author":"Kim","year":"2015","journal-title":"Int Neurourol J"},{"key":"R23-20240828","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1447-056X-10-7","article-title":"In a free healthcare system, why do men not consult for lower urinary tract symptoms (LUTS)?","volume":"10","author":"Lai","year":"2011","journal-title":"Asia Pac Fam Med"},{"key":"R24-20240828","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/S0090-4295(00)00894-3","article-title":"Influence of sociodemographic and health status variables on the American Urological Association symptom scores in patients with lower urinary tract symptoms","volume":"57","author":"Badia","year":"2001","journal-title":"Urology"},{"key":"R25-20240828","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/luts.12100","article-title":"Prevalence of lower urinary tract symptoms among individuals aged 50 years and over and its effect on the quality of life in a semi-rural area of western Turkey","volume":"9","author":"Arslantas","year":"2017","journal-title":"Low Urin Tract Symptoms"},{"key":"R26-20240828","first-page":"42","article-title":"Co-treatment of lower urinary tract symptoms and cardiovascular disease-Where do we stand?","volume":"73","author":"Semczuk-Kaczmarek","year":"2020","journal-title":"Cent European J Urol"},{"key":"R27-20240828","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.urology.2008.11.051","article-title":"Efficacy of combined amlodipine\/terazosin therapy in male hypertensive patients with lower urinary tract symptoms: A randomized, double-blind clinical trial","volume":"74","author":"Liu","year":"2009","journal-title":"Urology"},{"key":"R28-20240828","first-page":"543","article-title":"Evaluation of the clinical efficacy and complications of duloxetine in comparison to solifenacin in the treatment of overactive bladder disease in women: A randomized clinical trial","volume":"18","author":"Mirzaei","year":"2021","journal-title":"Urol J"},{"key":"R29-20240828","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1186\/s12894-022-01133-1","article-title":"An evaluation of lower urinary tract symptoms in diabetic patients: A cross-sectional study","volume":"22","author":"Qasrawi","year":"2022","journal-title":"BMC Urol"},{"key":"R30-20240828","first-page":"O78","article-title":"Effect of lower urinary tract symptoms on the quality of life and sexual function of males in China, Taiwan, and South Korea: Subgroup analysis of a cross-sectional, population-based study","volume":"11","author":"Liao","year":"2019","journal-title":"Low Urin Tract Symptoms"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_231_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:58:21Z","timestamp":1787839101000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_231_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,26]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_231_24","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,26]]},"assertion":[{"value":"2023-02-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-28","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}