{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:28:28Z","timestamp":1787758108345,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,6]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Introduction:<\/jats:title>\n Vaccination against the global pandemic coronavirus disease 2019 (COVID-19) is a promising way out of the havoc caused by the disease. The clinico-radiological profile of COVID-19 patients in relation to the vaccination status is depicted in the present study.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n This is a retrospective observational imaging and hospital data-based study performed on 214 confirmed and clinically suspicious patients of COVID-19 who underwent high-resolution computed tomography (HRCT) scan of the thorax at the Department of Radio-Diagnosis of a tertiary medical center in the Himalayan foothills. The present study aims to evaluate the effect of vaccination on HRCT findings of COVID-19 populations.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Forty-three percent of the non-vaccinated population presented with severe HRCT scores (19\u201325) in comparison to only 11.5% of the study population who had taken both doses of vaccine (P = 0.018). Two doses of vaccination had a negative Pearson correlation coefficient with severe HRCT scores (\u20130.146). Co-morbidities had a significant correlation with HRCT severity score, with 61.5% diabetics and 63.33% of hypertensive patients showing scores >19 on HRCT.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Vaccination proves to be a game changer in the pandemic with two doses of vaccination having a significant negative correlation with COVID-19-induced severe pneumonitis on HRCT of the thorax.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_2355_21","type":"journal-article","created":{"date-parts":[[2022,6,30]],"date-time":"2022-06-30T10:17:00Z","timestamp":1656584220000},"page":"2938-2944","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Effect of vaccination on the HRCT profile of COVID-19 patients \u2013 A single-center experience"],"prefix":"10.4103","volume":"11","author":[{"given":"Rohit","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal","family":"Thakker","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richa","family":"Bahri Sharma","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manali","family":"Arora","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Sarda","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mehul","family":"Ahuja","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lovepreet","family":"Singh Randhawa","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv Kumar","family":"Azad","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, SGRRIM&HS, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,6,30]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"e19673","DOI":"10.2196\/19673","article-title":"Diagnostic value of imaging modalities for COVID-19: Scoping 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Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2355_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:01:50Z","timestamp":1787756510000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_2355_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":10,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_2355_21","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"2021-12-04","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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