{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:23:35Z","timestamp":1787765015179,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,12]]},"abstract":"<jats:p>Sarcoidosis is a multisystem granulomatous disorder of unknown etiology, primarily affecting the intrathoracic lymph node and the lung. The endobronchial involvement in sarcoidosis is not uncommon and may appear as nodules, cobblestoning, erythema, or plaque, but presentation as an endobronchial mass has been rarely described. We report here a 50-year-old gentleman who presented with nonproductive cough and dyspnea on exertion. Video bronchoscopy revealed a polypoid mass in the right lower lobe bronchus occluding the posterior basal segment, and bronchial biopsy revealed noncaseating granulomatous inflammation. Bronchoalveolar lavage (BAL) fluid was negative for tuberculosis, fungal infection, and malignancy. Mantoux test was negative, and serum angiotensin-converting enzyme was elevated. The diagnosis of sarcoidosis was made, and the patient was started on an oral corticosteroid. After treatment, the patient showed significant improvement in symptoms. This case report highlights a rare presentation of sarcoidosis as an endobronchial mass lesion. It is important to take a biopsy to differentiate from other common causes of endobronchial mass, such as malignancy and, rarely, tuberculosis. Sarcoidosis should be considered in a differential of the endobronchial mass lesion.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_255_23","type":"journal-article","created":{"date-parts":[[2023,12,18]],"date-time":"2023-12-18T16:06:33Z","timestamp":1702915593000},"page":"3399-3401","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Sarcoidosis present as endobronchial lung mass: A rare case report with review of literature"],"prefix":"10.4103","volume":"12","author":[{"given":"Deependra Kumar","family":"Rai","sequence":"first","affiliation":[{"name":"Department of Pulmonary Medicine, AIKIMS, Patna, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Ruban Hospital, Patna, Bihar, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,12,21]]},"reference":[{"key":"R1-20260511","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1164\/rccm.201006-0865CI","article-title":"A concise review of pulmonary sarcoidosis","volume":"183","author":"Baughman","year":"2011","journal-title":"Am J Respir Crit Care Med"},{"key":"R2-20260511","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.mayocp.2015.10.024","article-title":"Epidemiology of sarcoidosis 1946-2013: A population-based study","volume":"91","author":"Ungprasert","year":"2016","journal-title":"Mayo Clin Proc"},{"key":"R3-20260511","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1034\/j.1399-3003.1999.13d01.x","article-title":"Fatigue and sarcoidosis","volume":"13","author":"Sharma","year":"1999","journal-title":"Eur Respir J"},{"key":"R4-20260511","doi-asserted-by":"crossref","first-page":"S47","DOI":"10.4103\/0973-3698.332978","article-title":"Pulmonary sarcoidosis","volume":"16","author":"Talwar","year":"2021","journal-title":"Indian J Rheumatol"},{"key":"R5-20260511","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1148\/rg.306105512","article-title":"Pulmonary sarcoidosis: Typical and atypical manifestations at high-resolution CT with pathologic correlation","volume":"30","author":"Criado","year":"2010","journal-title":"Radiographics"},{"key":"R6-20260511","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1378\/chest.111.3.619","article-title":"Endobronchial disease and racial differences in pulmonary sarcoidosis","volume":"111","author":"Torrington","year":"1997","journal-title":"Chest"},{"key":"R7-20260511","doi-asserted-by":"crossref","first-page":"274","DOI":"10.4046\/trd.2013.74.6.274","article-title":"A case of pulmonary sarcoidosis with endobronchial nodular involvement","volume":"74","author":"Cho","year":"2013","journal-title":"Tuberc Respir Dis (Seoul)"},{"key":"R8-20260511","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1136\/thx.38.2.157","article-title":"Endobronchial mass lesion due to sarcoidosis: Complete resolution with corticosteroids","volume":"38","author":"Corsello","year":"1983","journal-title":"Thora\u00d7"},{"key":"R9-20260511","first-page":"256","article-title":"A case of endobronquial sarcoidosis presenting as a polipoid lesion","volume":"40","author":"Ishii","year":"2002","journal-title":"Nihon Kokyuki Gakkai Zasshi"},{"key":"R10-20260511","first-page":"190","article-title":"Multiple endobronquial mass lesions due to sarcoidosis","volume":"51","author":"Kumbasar","year":"2003","journal-title":"Tuberk Toraks"},{"key":"R11-20260511","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.rmedx.2005.12.001","article-title":"Endobronchial sarcoid mass: Uncommon presentation of the disease","volume":"2","author":"Ortega-Gonz\u00e1lez","year":"2006","journal-title":"Respir Med Extra"},{"key":"R12-20260511","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/LBR.0b013e3181604f49","article-title":"Rare manifestation of sarcoidosis as endobronchial mass","volume":"15","author":"Thomas","year":"2008","journal-title":"J Bronchol"},{"key":"R13-20260511","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.rmedx.2005.12.004","article-title":"A rare presentation of sarcoidosis as a polypoid endobronchial structure","volume":"2","author":"Kami\u0144ski","year":"2006","journal-title":"Respir Med Extra"},{"key":"R14-20260511","first-page":"78","article-title":"A case of sarcoidosis with multiple endobronchial mass lesions that disappeared with antibiotics","volume":"23","author":"Baba","year":"2006","journal-title":"Sarcoidosis Vasc Diffuse Lung Dis"},{"issue":"Suppl 53","key":"R15-20260511","first-page":"691","article-title":"(Ankara, Turkey). 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