{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:28:51Z","timestamp":1786649331795,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","license":[{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>A 28-year-old male presented to our outdoor clinic with uncontrolled hypertension. He was diagnosed incidentally with hypertension at the age of 16 years. He was taking multiple anti-hypertensive medications but his home blood pressure (BP) readings were always on higher side. He had history of ambiguous genitalia at birth and underwent corrective surgery in early childhood. He had history of poor beard growth for that he received testosterone injections for almost a year. He had elevated BP (170\/90 mm\/Hg). On the Examination, he had poor secondary sexual characters with ambiguous genitalia (external masculinization score = 2\/15), with bilateral ectopic testes in inguinal canal. Hormonal analysis revealed low testosterone with elevated follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels. Considering the clinical profile, possibility of disorder of sexual differentiation due to 17 alpha hydroxylase was kept. Steroid profiling was sent that confirmed the diagnosis. The patient was initiated on a treatment regimen including oral hydrocortisone, parenteral testosterone and Aldactone.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_259_25","type":"journal-article","created":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T10:01:04Z","timestamp":1776679264000},"page":"1442-1444","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Young onset hypertension \u2013 underdiagnosed and undertreated \u2013 a rare case presentation"],"prefix":"10.4103","volume":"15","author":[{"given":"Rohit","family":"Raina","sequence":"first","affiliation":[{"name":"Department of General Medicine, AIIMS, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preeti Singh","family":"Dhoat","sequence":"additional","affiliation":[{"name":"Department of General Medicine, AIIMS, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Arun","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of General Medicine, AIIMS, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of Endocrinology and Metabolism, AIIMS, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amandeep","family":"Kaur","sequence":"additional","affiliation":[{"name":"Department of General Medicine, AIIMS, Bathinda, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,20]]},"reference":[{"key":"R1-20260424","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1161\/HYPERTENSIONAHA.119.13820","article-title":"Investigation and treatment of high blood pressure in young people:Too much medicine or appropriate risk reduction?","volume":"75","author":"Hinton","year":"2020","journal-title":"Hypertension"},{"key":"R2-20260424","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1111\/j.1651-2227.1992.tb12213.x","article-title":"A single pediatric center experience with 1025 children with hypertension","volume":"81","author":"Wyszy\u0144ska","year":"1992","journal-title":"Acta Paediatr"},{"key":"R3-20260424","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0929-6646(09)60342-9","article-title":"Seventeen Alpha-hydroxylase Deficiency","volume":"105","author":"Wong","year":"2006","journal-title":"J Formos Med Assoc"},{"key":"R4-20260424","first-page":"22","article-title":"Diagnosis of 17-alpha hydroxylase deficiency performed late in life in a patient with a 46, XY karyotype","author":"Bou\u00e7a","year":"2023","journal-title":"Endocrinol Diabetes Metabo Case Rep. 2023"},{"key":"R6-20260424","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.jsbmb.2016.02.002","article-title":"Steroid 17-hydroxylase and 17,20-lyase deficiencies, genetic and pharmacologic","volume":"165","author":"Auchus","year":"2017","journal-title":"J Steroid Biochem Mol Biol"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_259_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T18:52:29Z","timestamp":1786647149000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_259_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":5,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_259_25","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-02-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-19","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}