{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:46:29Z","timestamp":1786718789923,"version":"build-2736575974"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Family Med Prim Care"],"published-print":{"date-parts":[[2019]]},"DOI":"10.4103\/jfmpc.jfmpc_297_18","type":"journal-article","created":{"date-parts":[[2019,1,30]],"date-time":"2019-01-30T08:13:02Z","timestamp":1548835982000},"page":"62","source":"Crossref","is-referenced-by-count":18,"title":["Preintensive care: Thrombolytic (streptokinase or tenecteplase) in ST elevated acute myocardial infarction at peripheral hospital"],"prefix":"10.4103","volume":"8","author":[{"given":"HimmatraoS","family":"Bawaskar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"PramodiniH","family":"Bawaskar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"ParagH","family":"Bawaskar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/2249-4863.251166-1","first-page":"15","volume-title":"Systems of care for ST-elevated myocardial infarction in India","author":"Alexander","year":"2012","journal-title":"Heart"},{"key":"key-10.4103\/2249-4863.251166-2","first-page":"13","volume-title":"Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: A quantitative review of 23 randomized trial","author":"Keeley","year":"2003","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-3","first-page":"1435","volume-title":"Treatment and outcomes of acute coronary syndromes in India (CREATE): A prospective analysis of registry data","author":"Xvier","year":"2008","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-4","first-page":"121","volume-title":"Presentation, management and outcomes 25748 acute coronary syndrome admission in Kerala, India: Result from Kerala ACS registry","author":"Mohanan","year":"2013","journal-title":"Eur Heart J"},{"key":"key-10.4103\/2249-4863.251166-5","first-page":"291","volume-title":"Alternative projections of mortality and disability by cause 1990-2020: Global burden disease study","author":"Murry","year":"1997","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-6","first-page":"16","volume-title":"Epidemiological and causation of coronary heart disease and stroke in India","author":"Gupta","year":"2008","journal-title":"Heart J"},{"key":"key-10.4103\/2249-4863.251166-7","first-page":"807","volume-title":"Burden of non-communicable disease in south Asia","author":"Ghaffar","year":"2004","journal-title":"BMJ"},{"key":"key-10.4103\/2249-4863.251166-8","first-page":"1332","volume-title":"Educational status, coronary heart disease and coronary risk factor prevalence in rural population of India","author":"Gupta","year":"1994","journal-title":"BMJ"},{"key":"key-10.4103\/2249-4863.251166-9","first-page":"775","volume-title":"Vitamin B12 deficiency and homocysteinemia in rural and urban Indian","author":"Yajnik","year":"2006","journal-title":"J Assoc Physician India"},{"key":"key-10.4103\/2249-4863.251166-10","first-page":"111","volume-title":"Vascular pathology of homocysteinemia: Implication of the pathogenesis of arteriosclerosis","author":"McCully","year":"1965","journal-title":"Am J Pathol"},{"key":"key-10.4103\/2249-4863.251166-11","doi-asserted-by":"crossref","unstructured":"Falk E, Shah PK, Fuster V. Coronary plaque disruption. Circulation 1995;92;657-71.","DOI":"10.1161\/01.CIR.92.3.657"},{"key":"key-10.4103\/2249-4863.251166-12","first-page":"365","volume-title":"Current concepts of the pathogenesis of the acute coronary syndrome","author":"Libby","year":"2001","journal-title":"Circulation"},{"key":"key-10.4103\/2249-4863.251166-13","first-page":"1297","volume-title":"Effect of thrombolytic treatment delays on myocardial infarct size","author":"Hermens","year":"1992","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-14","first-page":"38","volume-title":"Aborted myocardial infarction in patient with ST-segment elevation insight from the assessment of the safety and efficacy of a new thrombolytic regimen-3 trial electrocardiographic subsidy","author":"Taher","year":"2004","journal-title":"J Am Coll Cardiol"},{"key":"key-10.4103\/2249-4863.251166-15","first-page":"979","volume-title":"Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: Is the slope of the curve the shape of the future?","author":"Gersh","year":"2005","journal-title":"JAMA"},{"key":"key-10.4103\/2249-4863.251166-16","unstructured":"Department of health vascular programme team. Treatment of heart attack national guidance. Final report of the national infarct Angioplasty project (NIAP), 2008. Available from: http:\/\/www.bcis.org.uk. [Last accessed on 1914 Dec 15]."},{"key":"key-10.4103\/2249-4863.251166-17","first-page":"8","volume-title":"A systemic review of factors predicting door to balloon time in ST-segment elevation myocardial infarction","author":"Peterson","year":"2012","journal-title":"Int J Cardiol"},{"key":"key-10.4103\/2249-4863.251166-18","first-page":"1379","volume-title":"Fibrinolysis or primary PCI in ST-elevated myocardial infarction","author":"Armstrong","year":"2013","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2249-4863.251166-19","first-page":"2569","volume-title":"Steg OG, James SK, Atar D, Badano LP, Bl\u00f6mstrom-Lundqvist C, Borger MA, et al. ESC guidelines for the management of acute myocardial infarction in patients presenting with ST \u2013segment elevation","author":"Task","year":"2012","journal-title":"Eur Heart J"},{"key":"key-10.4103\/2249-4863.251166-20","first-page":"485","volume-title":"2013 ACCF\/AHA guideline for management of ST-elevated myocardial infarction: Excutive summary.A report of the American College of Cardiology Foundation\/American Heart Association Task Force on practice Guidelines","author":"American","year":"2013","journal-title":"J Am Coll Cardiol"},{"key":"key-10.4103\/2249-4863.251166-21","first-page":"716","volume-title":"Single \u2013bolus tenecteplase compared with front loaded alteplase in acute myocardi infarction: ASSENT -2 double \u2013blind randomized trial","author":"Van","year":"199;","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-22","first-page":"383","volume-title":"Prehospital thrombolytic therapy in patients with suspected acute myocardial infarction","author":"The","year":"1993","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2249-4863.251166-23","first-page":"135","volume-title":"Efficacy and safety of tenecteplase in combination with the low-molecular-weight heparin enoxaparin or unfractionated heparin in prehospital setting: The assessment of safety and efficacy of a New thrombolytic regimen (ASSENT)-3 PLUS randomized trial in acute myocardial infarction","author":"Wallentin","year":"2003","journal-title":"Circulation"},{"key":"key-10.4103\/2249-4863.251166-24","first-page":"2851","volume-title":"Impact of time to treatment on mortality after pre-hospital fibrinolysis or primary angioplasty data from CAPTIM randomized clinical trial","author":"Steg","year":"2003","journal-title":"Circulation"},{"key":"key-10.4103\/2249-4863.251166-25","first-page":"557","volume-title":"Unsuccessful reperfusion patient with ST-elevation myocardial infarction treated by primary angioplasty","author":"De","year":"2005","journal-title":"Am Heart J"},{"key":"key-10.4103\/2249-4863.251166-26","first-page":"827","volume-title":"Preprocedural thrombolysis in myocardial infarction (TIMI) flow significantly affects the extent of ST-segment resolution and myocardial blush in patients with acute anterior myocardial infarction treated with primary angioplasty","author":"De","year":"2005","journal-title":"Am Heart J"},{"key":"key-10.4103\/2249-4863.251166-27","first-page":"2758","volume-title":"for the REACT trial investigators.Rescue angioplasty after failed thrombolytic therapy for acute myocardial infarction","author":"Gershlick","year":"2005","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2249-4863.251166-28","first-page":"570","volume-title":"Acute myocardial infarction","author":"White","year":"2008","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-29","first-page":"579","volume-title":"Comparison of primary and facilitated percutaneous coronary interventions for ST-elevation myocardial infarction: Quantitative review of randomized trials","author":"Keeley","year":"2006","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-30","first-page":"1045","volume-title":"Routine invasive strategy within 24 hours of thrombolysis versus ischemia\u2013guided conservative approach for acute myocardial infarction with ST\u2013segment elevation (GARCIA-1): A randomized controlled trial","author":"Fernandez","year":"2004","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-31","first-page":"2205","volume-title":"Facilliated PCI in patients with ST-elevation myocardial infarction","author":"Ellis","year":"2008","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2249-4863.251166-32","first-page":"81","volume-title":"Collaborative overview of randomized trials of antiplatelet therapy-1: Prevention of death.Myocardial infarction, and stroke by prolonged antiplate therapy in various categories of patients","author":"Antiplatelet","year":"1994","journal-title":"BMJ"},{"key":"key-10.4103\/2249-4863.251166-33","doi-asserted-by":"crossref","unstructured":"Antithrombotic Trialists' Collaboration. Collarative meta-analysis of randomized trials of antiplatelet therapy for prevention of death, myocardial infarction and stroke in high risk patient. Erratum. Available from: http:\/\/bmj.com\/cgs\/content\/full\/324\/7329\/71\/DC2. BMJ 2002;324:71-86. [Last accessed on 1914 Dec 15].","DOI":"10.1136\/bmj.324.7329.71"},{"key":"key-10.4103\/2249-4863.251166-34","first-page":"1179","volume-title":"Addition of clopidogrel to asprin and fibrinolytic therapy for myocardial infarction with ST- segment elevation","author":"Sabatine","year":"2005","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2249-4863.251166-35","first-page":"2099","volume-title":"Randomized trial of high loading dose of clopidogrel for reduction of periprocedural myocardial infarction in patients undergoing coronary intervention: Results from b the ARMYDA2 (Antiplatelet therapy for reduction of Myocardial damage during angioplasty) study","author":"Patti","year":"2005","journal-title":"Circulation"},{"key":"key-10.4103\/2249-4863.251166-36","first-page":"83","volume-title":"Effect of \u201cfast track\u201d admission for acute myocardial infarction on delay to thrombolysis","author":"Pell","year":"1992","journal-title":"BMJ"},{"key":"key-10.4103\/2249-4863.251166-37","first-page":"1327","volume-title":"for the LATE study investigators.Late assessment of thrombolytic efficacy (LATE) study: Prognosis in patients with non-Q wave myocardial infarction","author":"Langer","year":"1996","journal-title":"J Am Coll Cardiol"},{"key":"key-10.4103\/2249-4863.251166-38","first-page":"2001","volume-title":"for the TRITON-TIMI 38 investigators.Prasugrel versus clopidogrel in patients with acute coronary syndrome","author":"Wiviott","year":"2007","journal-title":"N Engl J Med"},{"key":"key-10.4103\/2249-4863.251166-39","first-page":"1287","volume-title":"Coronary thrombolytic treatment at home","author":"Petch","year":"1991","journal-title":"BMJ"},{"key":"key-10.4103\/2249-4863.251166-40","first-page":"955","volume-title":"Violence against doctors in India","author":"Bawaskar","year":"2014","journal-title":"Lancet"},{"key":"key-10.4103\/2249-4863.251166-41","doi-asserted-by":"crossref","unstructured":"O' donnell M. Battle of the c Clotbusters. BMJ 1991;302:1259-61","DOI":"10.1136\/bmj.302.6787.1259"},{"key":"key-10.4103\/2249-4863.251166-42","doi-asserted-by":"crossref","unstructured":"(Editorial) Cardiovascular health for all - Lancet 2013; 382: 572.","DOI":"10.1016\/S0140-6736(13)61730-4"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:39:49Z","timestamp":1786714789000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_297_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019]]}},"alternative-id":["251166"],"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_297_18","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}