{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:26:05Z","timestamp":1787775965542,"version":"build-2784847793"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n The present study aims to evaluate the etiological spectrum with clinicopathological parameters and adverse outcomes of acute kidney injury (AKI).<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n A hospital-based prospective observational study was conducted for a spectrum of AKI in 103 AKI patients and their AKI-associated adverse outcomes. The AKI patients were included as per the KDIGO definition. The patients with a known chronic kidney disease (CKD) were excluded from the study population. A clinicopathological association with AKI was observed. Adverse outcomes and the need for renal biopsy were recorded in 3 weeks followed up to 6 months.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n A single-center study recorded that the incidence of AKI was 8.6% with a mean age of 34 \u00b1 16 years. The cause of AKI due to medical reasons was maximum (70.8%), followed by obstetric (21.3%) and surgery (7.7%). The AKI mortality rate was 16% (\n P<\/jats:italic>\n < 0.05). Renal biopsy in 34 cases showed that acute tubular necrosis was higher (38%), followed by acute cortical necrosis (23%). The spectrum of AKI was very diverse. In the 6-month follow-up, the adverse outcome was observed in 27.2% of patients, where the mortality rate was 16.5% and 10.7% of patients progressed to CKD.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The spectrum of AKI was diverse among the population, and most of the etiologies are preventable. This alarms the need for better preventive strategies with a better referral system. The obstetric population with AKI, which majorly leads to either mortality or progression to CKD, is the section that seeks more attention.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_366_24","type":"journal-article","created":{"date-parts":[[2024,10,18]],"date-time":"2024-10-18T01:02:50Z","timestamp":1729213370000},"page":"4371-4376","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Etiological spectrum of acute kidney injury and adverse outcome: A single-center observation"],"prefix":"10.4103","volume":"13","author":[{"given":"Nikunj Kishore","family":"Rout","sequence":"first","affiliation":[{"name":"Department of Nephrology, Kalinga Institute of Medical Science, KIIT DU, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arpita Ray","family":"Choudhury","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Institute of Post Graduate Medical Education and Research, Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Dasgupta","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Calcutta Medical College, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Debasis","family":"Pathi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Kalinga Institute of Medical Science, KIIT DU, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bandita","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Research and Development, Kalinga Institute of Medical Science, KIIT DU, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajendra","family":"Pandey","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Institute of Post Graduate Medical Education and Research, Seth Sukhlal Karnani Memorial Hospital, Kolkata, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,18]]},"reference":[{"key":"R1-20250114","doi-asserted-by":"crossref","first-page":"844","DOI":"10.2215\/CJN.05191107","article-title":"Diagnosis, epidemiology, and outcomes of acute kidney injury","volume":"3","author":"Waikar","year":"2008","journal-title":"Clin J Am Soc Nephrol"},{"key":"R2-20250114","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1053\/j.ajkd.2009.06.027","article-title":"Five decades of Indian nephrology: A personal journey","volume":"54","author":"Chugh","year":"2009","journal-title":"Am J Kidney Dis"},{"key":"R3-20250114","first-page":"504","article-title":"Acute renal failure in south India. 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